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Michele Lambert, MD
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Journal Articles

Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study

Breakey R. Vicky, MD MD FRCPC, Rachael F Grace, MD, Carolyn M. Bennett, Jenny M. Despotovic, DO, MS, Jennifer A Rothman, MD, Yves D. Pastore, MD, Ellis J Neufeld, MD PhD, Robert J. Klaassen, MD, Michele Lambert, MD, James B. Bussel, MD, George R. Buchanan, MD, Melissa J. Rose, DO, Amy E. Geddis, MD PhD, Kristin Shimano, MD, Kerry Hege, MD, Kristina M. Haley, DO, Adonis Lorenzana, MD, Alexis A. Thompson, MD MPH, Michael Jeng, MD, Shelley E. Crary, MD MSCS, Michelle Neier, MD, Travis Brown, Peter Forbes, BS, Cindy Neunert, MD
Journal: Blood
Blood (2016) 128 (22): 4752.
https://doi.org/10.1182/blood.V128.22.4752.4752
Published: 2016
Journal Articles

Clinical Characteristics and Quality of Life of Children with ITP Starting Second Line Treatments: Data from the ITP Consortium of North America ICON1 Study

Rachael F Grace, MD, Robert J. Klaassen, MD, Jennifer A Rothman, MD, Kerry Hege, MD, Ellis J Neufeld, MD PhD, Carolyn M. Bennett, Michele Lambert, MD, Vicky R. Breakey, BSc, MD MD FRCPC, James B. Bussel, MD, George R. Buchanan, MD, Melissa J. Rose, DO, Amy Geddis, MD PhD, Kristin Shimano, MD, Kristina M. Haley, DO, Adonis Lorenzana, MD, Cindy Neunert, MD, Alexis A. Thompson, MD MPH, Yves D. Pastore, MD, Michael Jeng, MD, Shelley E. Crary, MD MSCS, Michelle Neier, MD, Travis Brown, Peter Forbes, BS, Jenny M. Despotovic, DO, MS
Journal: Blood
Blood (2016) 128 (22): 249.
https://doi.org/10.1182/blood.V128.22.249.249
Published: 2016
Journal Articles

Platelet Factor 4 (PF4) Causes Cell Cycle Arrest in Megakaryocytes (Megs) by Inactivating CDC2 (CDK1) and CDK2

Liqing Xiao, PhD, Mortimer Poncz, MD, Michele Lambert, MD
Journal: Blood
Blood (2012) 120 (21): 1238.
https://doi.org/10.1182/blood.V120.21.1238.1238
Published: 2012
Journal Articles

Platelet Factor 4 (PF4) Is Selectively Recycled During Megakaryopoiesis

Michele Lambert, MD, Liqing Xiao, PhD, Ronghua Meng, PhD, Michael S. Marks, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2012) 120 (21): 388.
https://doi.org/10.1182/blood.V120.21.388.388
Published: 2012
Journal Articles

2-O, 3-O-Desulfated Heparin (ODSH) Mitigates Chemotherapy-Induced Thrombocytopenia (CIT) by Blocking the Negative Paracrine Effect of Platelet Factor 4 (PF4) On Megakaryopoiesis

Michele Lambert, MD, Samriddhi S Sharma, Liqing Xiao, PhD, Stephen Marcus, MD, Mortimer Poncz, MD
Journal: Blood
Blood (2012) 120 (21): 386.
https://doi.org/10.1182/blood.V120.21.386.386
Published: 2012
Journal Articles

Tissue-Specific Transgene Expression in Induced Pluripotent Stem (iPS) Cell-Derived Megakaryocytes: Correction of Glanzmann Thrombasthenia (GT)

Spencer K. Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Karen Vo, Michele Lambert, MD, Sevasti B. Koukouritaki, PhD, Juan Fang, MD, David A. Wilcox, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD
Journal: Blood
Blood (2012) 120 (21): 387.
https://doi.org/10.1182/blood.V120.21.387.387
Published: 2012
Journal Articles

Platelet Factor 4 (PF4) Levels Are Inversely Correlated with Steady-State Platelet Counts and with Nadir Counts in Chemotherapy-Induced Thrombocytopenia (CIT),

Michele Lambert, MD, Alisa Reznikov, Liqing Xiao, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2011) 118 (21): 3527.
https://doi.org/10.1182/blood.V118.21.3527.3527
Published: 2011
Journal Articles

Targeted Gene Correction of Glanzmann Thrombasthenia Induced Pluripotent Stem Cells Restores Surface Expression and Fibrinogen Binding of Integrin αIIbβ3,

Spencer Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Guohua Zhao, PhD, Lin Lu, PhD, Michele Lambert, MD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD
Journal: Blood
Blood (2011) 118 (21): 4173.
https://doi.org/10.1182/blood.V118.21.4173.4173
Published: 2011
Journal Articles

A Novel Mutation in MPL (Y252H) Results in Increased Thrombopoietin Sensitivity and Moderate Thrombocytosis in a Pediatric Patient with Essential Thrombocytosis

Michele Lambert, MD, Jing Jiang, Wei Tong
Journal: Blood
Blood (2011) 118 (21): 2817.
https://doi.org/10.1182/blood.V118.21.2817.2817
Published: 2011
Journal Articles

Platelet Factor 4 Levels Inversely Correlate with Platelet Transfusion Needs In Pediatric Patients Treated for Standard Risk Acute Lymphoblastic Leukemia

Michele Lambert, MD, Alisa Reznikov, Yvonne Nguyen, Lubica Rauova, Mortimer Poncz, MD
Journal: Blood
Blood (2010) 116 (21): 725.
https://doi.org/10.1182/blood.V116.21.725.725
Published: 2010
Journal Articles

Response to Steroids Predicts Response to Rituximab In Pediatric Chronic Immune Thrombocytopenia.

Rachael F. Grace, MD, Carolyn M. Bennett, MD, MS, A. Kim Ritchey, MD, Michael R. Jeng, MD, Courtney Thornburg, MD, MS, Michele Lambert, MD, Michelle Neier, MD, Michael Recht, MD, PhD, Manjusha Kumar, MD, Victor Blanchette, MD, Robert Klaassen, MD, FRCP, George R. Buchanan, MD, Margaret A. Heisel Kurth, MD, Diane J. Nugent, MD, Alexis A. Thompson, MD, MPH, Kimo Stine, MD, Leslie A. Kalish, ScD, Ellis J. Neufeld, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3681.
https://doi.org/10.1182/blood.V116.21.3681.3681
Published: 2010