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Melinda Varney
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Journal Articles

Tifab Deficiency Protects Against Stress-Induced Bone Marrow Failure at the Expense of Pre-Leukemic Selection

Madeline Niederkorn, BS, Melinda Varney, PhD, Ken Greis, PhD, Ruhikanta A. Meetei, PhD, Kwangmin Choi, PhD, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2960.
https://doi.org/10.1182/blood.V130.Suppl_1.2960.2960
Published: 2017
Journal Articles

Innate Immune Signal Pathway Activation Induced By Combined Loss of Del(5q) MDS Genes, Tifab and Mir-146a, Accelerates Hematopoietic Stem Cell Exhaustion Driven By Chronic Exposure to a TLR Ligands

Tomoya Muto, MD PhD, Melinda Varney, PhD, Callum Walker, MSc, Lyndsey Bolanos, BSc, Kathleen Hueneman, BSc, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1674.
https://doi.org/10.1182/blood.V130.Suppl_1.1674.1674
Published: 2017
Journal Articles

Tifab , a Del(5q) MDS/AML Gene, Regulates USP15 Activity and p53

Madeline Niederkorn, BS, Melinda Varney, PhDBS, Molly A Smith, BS, Ruhikanta A. Meetei, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2016) 128 (22): 1130.
https://doi.org/10.1182/blood.V128.22.1130.1130
Published: 2016
Journal Articles

Deletion Of Tifab, a Novel Candidate Gene On Chromosome 5q, Results In Hematopoietic Defects By Changing The Dynamic Range Of Innate Immune Pathway Activation

Melinda Varney, PhD, Susanne Christie, Madeline Niederkorn, Jing Fang, MD, PhD, Andres Jerez, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Jun-ichiro Inoue, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2013) 122 (21): 102.
https://doi.org/10.1182/blood.V122.21.102.102
Published: 2013
Journal Articles

Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML.

Melinda Varney, PhD, Andres Jerez, MD, PhD, Jing Fang, MD/PhD, David Miller, Lyndsey Bolanos, BSc, Aly Karsan, MD, Jaroslaw P. Maciejewski, MD, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2012) 120 (21): 2812.
https://doi.org/10.1182/blood.V120.21.2812.2812
Published: 2012
Journal Articles

Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

Jing Fang, Garrett Rhyasen, Lyndsey Bolanos, Christopher Rasch, Melinda Varney, Mark Wunderlich, Susumu Goyama, Gerrit Jansen, Jacqueline Cloos, Carmela Rigolino, Agostino Cortelezzi, James C. Mulloy, Esther N. Oliva, Maria Cuzzola, Daniel T. Starczynowski
Journal: Blood
Blood (2012) 120 (4): 858–867.
https://doi.org/10.1182/blood-2012-02-407999
Published: 2012
Includes: Supplemental data