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Journal Articles

Innate Immune Signal Pathway Activation Induced By Combined Loss of Del(5q) MDS Genes, Tifab and Mir-146a, Accelerates Hematopoietic Stem Cell Exhaustion Driven By Chronic Exposure to a TLR Ligands

Tomoya Muto, MD PhD, Melinda Varney, PhD, Callum Walker, MSc, Lyndsey Bolanos, BSc, Kathleen Hueneman, BSc, Daniel Starczynowski, PhD

Blood (2017) 130 (Supplement 1): 1674.

https://doi.org/10.1182/blood.V130.Suppl_1.1674.1674

Published: 2017

Journal Articles

Inhibition of UBE2N As a Therapeutic Approach in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Laura Barreyro, PhD, Avery M Sampson, BS, Lyndsey Bolanos, BSc, Madeline Niederkorn, BS, Mario Pujato, PhD, Molly A Smith, BS, Muto Tomoya, MD PhD, Wendy D Haffey, PhD, Susanne Christie, Xiaona Liu, MD MS, Matthew Weirauch, PhD, Ken Greis, PhD, William L Seibel, PhD, Daniel T Starczynowski, PhD

Blood (2016) 128 (22): 579.

https://doi.org/10.1182/blood.V128.22.579.579

Published: 2016

Journal Articles

TRAF6 Is Essential for Maintaining Hematopoietic Stem Cell Homeostasis

Jing Fang, MD PhD, Lyndsey Bolanos, BSc, Juana Serrano-Lopez, PhD, Susanne Christie, Jose A Cancelas, MD PhD, Daniel T Starczynowski, PhD

Blood (2016) 128 (22): 568.

https://doi.org/10.1182/blood.V128.22.568.568

Published: 2016

Journal Articles

Ubiquitin Editing of a Spliceosome Auxiliary Factor By TRAF6 Links Chronic TLR Signaling with Hematopoietic Defects and Myelodysplasia

Jing Fang, MD, PhD, Lyndsey Bolanos, BSc, Kwang-Min Choi, PhD, Xiaona Liu, Ms, Susanne Christie, Shailaja Akunuru, PhD, Rupali Kumar, PhD, Ken Greis, PhD, Peter Stoilov, PhD, Marie-Dominique Filippi, PhD, Jaroslaw P. Maciejewski, MD PhD, Guillermo Garcia-Manero, MD, Matthew Weirauch, PhD, Nathan Salomonis, PhD, Hartmut Geiger, PhD, Yi Zheng, PhD, Daniel Starczynowski, PhD

Blood (2015) 126 (23): 143.

https://doi.org/10.1182/blood.V126.23.143.143

Published: 2015

Journal Articles

A Calcium-Dependent Pathway Determines Response to Lenalidomide in Del(5q) Myelodysplastic Syndromes

Jing Fang, MD PhD, Xiaona Liu, BSc, Lyndsey Bolanos, BSc, Brenden Barker, BSc, Carmela Rigolino, BSc, Agostino Cortelezzi, MD, Esther Natalie Oliva, MD, Kyle J MacBeth, PhD, Kakajan Komurov, PhD, Daniel T Starczynowski, PhD

Blood (2014) 124 (21): 1898.

https://doi.org/10.1182/blood.V124.21.1898.1898

Published: 2014

Journal Articles

Disease-Relevant Expression Of TRAF6 In Mouse HSC Results In An MDS-Like Disease

Jing Fang, MD/PhD, Xiaona Liu, BSc, Brenden Barker, BSc, Lyndsey Bolanos, BSc, Yue Wei, PhD, Guillermo Garcia Manero, MD, Daniel T Starczynowski, PhD

Blood (2013) 122 (21): 101.

https://doi.org/10.1182/blood.V122.21.101.101

Published: 2013

Journal Articles

SQSTM1/p62 Is a Necessary Cofactor In MDS/AML With Deletion Of Mir-146a

Jing Fang, MD/PhD, Brenden Barker, BSc, Lyndsey Bolanos, BSc, Xiaona Liu, BSc, Andres Jerez, MD, PhD, Hideki Makishima, MD, PhD, Dinesh S. Rao, M.D., James C. Mulloy, PhD, Jaroslaw P. Maciejewski, MD, PhD, Jose A. Cancelas, M.D. PhD., Daniel T Starczynowski, PhD

Blood (2013) 122 (21): 747.

https://doi.org/10.1182/blood.V122.21.747.747

Published: 2013

Journal Articles

Haploinsufficiency of Mir-146a in High-Risk Del(5q) MDS/AML Requires an Intrachromosomal Gene Network Involving p62/TRAF6/NF-κB

Jing Fang, MD/PhD, Andres Jerez, MD, PhD, Christopher Rasch, BSc, Lyndsey Bolanos, BSc, Jaroslaw P. Maciejewski, MD, PhD, Daniel T Starczynowski, PhD

Blood (2012) 120 (21): 557.

https://doi.org/10.1182/blood.V120.21.557.557

Published: 2012

Journal Articles

Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML.

Melinda Varney, PhD, Andres Jerez, MD, PhD, Jing Fang, MD/PhD, David Miller, Lyndsey Bolanos, BSc, Aly Karsan, MD, Jaroslaw P. Maciejewski, MD, PhD, Daniel T Starczynowski, PhD

Blood (2012) 120 (21): 2812.

https://doi.org/10.1182/blood.V120.21.2812.2812

Published: 2012

Journal Articles

Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

Jing Fang, Garrett Rhyasen, Lyndsey Bolanos, Christopher Rasch, Melinda Varney, Mark Wunderlich, Susumu Goyama, Gerrit Jansen, Jacqueline Cloos, Carmela Rigolino, Agostino Cortelezzi, James C. Mulloy, Esther N. Oliva, Maria Cuzzola, Daniel T. Starczynowski

Blood (2012) 120 (4): 858–867.

https://doi.org/10.1182/blood-2012-02-407999

Published: 2012

Includes: Supplemental data

Journal Articles

Degradation of TRAF6 by Bortezomib-Induced Autophagy Contributes to Cell Death in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Jing Fang, MD/PhD, Lyndsey Bolanos, BSc, Garrett Rhyasen, BSc, Carmen Rigolino, BSc, Agostino Cortelezzi, MD, Esther Natalie Oliva, MD, Mariella Cuzzola, MD, Daniel T Starczynowski, PhD

Blood (2011) 118 (21): 2452.

https://doi.org/10.1182/blood.V118.21.2452.2452

Published: 2011

Journal Articles

Inhibition of IRAK1 As a Novel Therapeutic Strategy in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Garrett Rhyasen, BSc, Lyndsey Bolanos, BSc, Jing Fang, MD/PhD, Carmen Rigolino, BSc, Agostino Cortelezzi, MD, Esther Natalie Oliva, MD, Mariella Cuzzola, MD, Daniel T Starczynowski, PhD

Blood (2011) 118 (21): 612.

https://doi.org/10.1182/blood.V118.21.612.612

Published: 2011

NARROW

Innate Immune Signal Pathway Activation Induced By Combined Loss of Del(5q) MDS Genes, Tifab and Mir-146a, Accelerates Hematopoietic Stem Cell Exhaustion Driven By Chronic Exposure to a TLR Ligands

Inhibition of UBE2N As a Therapeutic Approach in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

TRAF6 Is Essential for Maintaining Hematopoietic Stem Cell Homeostasis

Ubiquitin Editing of a Spliceosome Auxiliary Factor By TRAF6 Links Chronic TLR Signaling with Hematopoietic Defects and Myelodysplasia

A Calcium-Dependent Pathway Determines Response to Lenalidomide in Del(5q) Myelodysplastic Syndromes

Disease-Relevant Expression Of TRAF6 In Mouse HSC Results In An MDS-Like Disease

SQSTM1/p62 Is a Necessary Cofactor In MDS/AML With Deletion Of Mir-146a

Haploinsufficiency of Mir-146a in High-Risk Del(5q) MDS/AML Requires an Intrachromosomal Gene Network Involving p62/TRAF6/NF-κB

Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML.

Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

Degradation of TRAF6 by Bortezomib-Induced Autophagy Contributes to Cell Death in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Inhibition of IRAK1 As a Novel Therapeutic Strategy in Acute Myeloid Leukemia and Myelodysplastic Syndrome

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American Society of Hematology

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