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Matthew Lawes
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Journal Articles

The Use of Avapritinib in Advanced Systemic Mastocytosis: Report of an Open-Label Compassionate Use Program in the United Kingdom

Christopher J. Saunders, Chandan Saha, Priya Sriskandarajah, Helen Cashman, Andrew J Wilson, Jonathan Lambert, Matthew Lawes, David Tucker, Simone Green, Manish Jain, Victoria Stables, Juanah Addada, Theingi Yin, Huw Roddie, Bethan Psaila, Deepti H. Radia
Journal: Blood
Blood (2022) 140 (Supplement 1): 3976–3977.
https://doi.org/10.1182/blood-2022-166073
Published: 2022
Journal Articles

Acute Myeloid Leukemia Export Mitochondria in Extracellular Vesicles Which Induces Pro-Tumoral Changes in Bone Marrow Macrophages

Jamie A Moore, BSc, MSc, Jayna J Mistry, BSc, Rebecca H Horton, Charlotte Hellmich, MBBChir, Adam Pattinson, MSc, BSc, Adam Morfakis, BSc, Yu Sun, BSc, MSc, PhD, Matthew Lawes, MD, Christopher J Morris, PhD, Anna Haestier, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1427.
https://doi.org/10.1182/blood-2019-128447
Published: 2019
Journal Articles

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts

Christopher R. Marlein, Lyubov Zaitseva, Rachel E. Piddock, Stephen D. Robinson, Dylan R. Edwards, Manar S. Shafat, Zhigang Zhou, Matthew Lawes, Kristian M. Bowles, Stuart A. Rushworth
Journal: Blood
Blood (2017) 130 (14): 1649–1660.
https://doi.org/10.1182/blood-2017-03-772939
Published: 2017
Includes: Supplemental data
Journal Articles

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment

Manar S. Shafat, Thomas Oellerich, Sebastian Mohr, Stephen D. Robinson, Dylan R. Edwards, Christopher R. Marlein, Rachel E. Piddock, Matthew Fenech, Lyubov Zaitseva, Amina Abdul-Aziz, Jeremy Turner, Johnathan A. Watkins, Matthew Lawes, Kristian M. Bowles, Stuart A. Rushworth
Journal: Blood
Blood (2017) 129 (10): 1320–1332.
https://doi.org/10.1182/blood-2016-08-734798
Published: 2017
Includes: Supplemental data