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Matthew D Blunt
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Journal Articles

Targeting CD161 in B-cell malignancies

Free
Matthew D. Blunt
Journal: Blood
Blood (2024) 143 (12): 1061–1062.
https://doi.org/10.1182/blood.2023023785
Published: 2024
Journal Articles

Selinexor Enhances Natural Killer Cell Function Against Multiple Myeloma Cells

Free
Jack G Fisher, Amber DP Doyle, Lara V Graham, Francesco Forconi, Mark S Cragg, Christopher J Walker, Salim I Khakoo, Matthew D Blunt
Journal: Blood
Blood (2023) 142 (Supplement 1): 6599.
https://doi.org/10.1182/blood-2023-179744
Published: 2023
Journal Articles

Selinexor Enhances NK Cell Activation Against Lymphoma Cells Via Downregulation of HLA-E

Free
Jack Fisher, Christopher J. Walker, Peter Johnson, Mark S Cragg, Francesco Forconi, Yosef Landesman, Salim I Khakoo, Matthew D Blunt
Journal: Blood
Blood (2021) 138 (Supplement 1): 2411.
https://doi.org/10.1182/blood-2021-144836
Published: 2021
Journal Articles

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Free
Matthew D Blunt, PhD, Lindsay D Smith, PhD, Adam Linley, PhD BSc, Jonathan C Strefford, PhD, Peter Johnson, Francesco Forconi, MD DM, PhD FRCPath, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4290.
https://doi.org/10.1182/blood.V130.Suppl_1.4290.4290
Published: 2017
Journal Articles

Regulation and Impact of BCR Induced Autophagy in Chronic Lymphocytic Leukemia

Free
Lindsay D Smith, PhD, Laura I Karydis, PhD, Margaret Ashton-Key, MD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Graham Packham, PhD, Mark Cragg, PhD, David A Tumbarello, PhD, Matthew D Blunt, PhD, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Steele, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1717.
https://doi.org/10.1182/blood.V130.Suppl_1.1717.1717
Published: 2017
Journal Articles

Releasing the brakes on BTK-targeting miRNA

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Matthew D. Blunt, Andrew J. Steele
Journal: Blood
Blood (2016) 128 (26): 3023–3024.
https://doi.org/10.1182/blood-2016-11-748145
Published: 2016
Journal Articles

Regulation of B-Cell Receptor Signalling By the Tumour Microenvironment in Chronic Lymphocytic Leukemia (CLL) and Its Impact on Adhesion and miRNA Expression

Free
Matthew D Blunt, PhD, Rachel Dobson, BSc(Hons), Lindsay D Smith, PhD, Jonathan C. Strefford, Pamela B. Conley, PhD, Anjali Pandey, PhD, Andrew J Davies, FRCP PhD, Peter M Johnson, MA, MD, Graham Packham, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath, Greg P Coffey, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2016) 128 (22): 351.
https://doi.org/10.1182/blood.V128.22.351.351
Published: 2016
Journal Articles

To BH3 profile or not to BH3 profile

Free
Matthew D. Blunt, Andrew J. Steele
Journal: Blood
Blood (2016) 127 (25): 3111–3112.
https://doi.org/10.1182/blood-2016-04-711762
Published: 2016
Journal Articles

IL-4 enhances expression and function of surface IgM in CLL cells

Free
Maria M. Aguilar-Hernandez, Matthew D. Blunt, Rachel Dobson, Alison Yeomans, Stephen Thirdborough, Marta Larrayoz, Lindsay D. Smith, Adam Linley, Jonathan C. Strefford, Andrew Davies, Peter M. W. Johnson, Natalia Savelyeva, Mark S. Cragg, Francesco Forconi, Graham Packham, Freda K. Stevenson, Andrew J. Steele
Journal: Blood
Blood (2016) 127 (24): 3015–3025.
https://doi.org/10.1182/blood-2015-11-682906
Published: 2016
Includes: Supplemental data
Journal Articles

Biological Significance of B Cell Receptor Mediated Regulation of Autophagy in Chronic Lymphocytic Leukemia

Free
Lindsay Smith, PhD, Elizabeth Hogg, BSc(Hons), Angus Haynes, Jonathan C Strefford, PhD, Francesco Forconi, MD DM, PhD FRCPath, Freda K Stevenson, DPhil, Graham Packham, PhD, Mark S Cragg, PhD, David Tumbarello, Matthew D Blunt, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2015) 126 (23): 4130.
https://doi.org/10.1182/blood.V126.23.4130.4130
Published: 2015
Journal Articles

The Syk\Jak Inhibitor Cerdulatinib (PRT062070) Shows Promising Preclinical Activity in Chronic Lymphocytic Leukemia By Antagonising B Cell Receptor and Microenvironmental Signalling

Free
Matthew D Blunt, PhD, Jack Parnell, BSc(hons), Marta Larrayoz, PhD, Lindsay Smith, PhD, Rachel Dobson, BSc(Hons), Jonathan C Strefford, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Davies, MRCP, Peter W Johnson, MD, Graham Packham, PhD, Greg P. Coffey, PhD, Mark S Cragg, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2015) 126 (23): 1716.
https://doi.org/10.1182/blood.V126.23.1716.1716
Published: 2015
Journal Articles

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

Free
Matthew D. Blunt, Matthew J. Carter, Marta Larrayoz, Lindsay D. Smith, Maria Aguilar-Hernandez, Kerry L. Cox, Thomas Tipton, Mark Reynolds, Sarah Murphy, Elizabeth Lemm, Samantha Dias, Andrew Duncombe, Jonathan C. Strefford, Peter W. M. Johnson, Francesco Forconi, Freda K. Stevenson, Graham Packham, Mark S. Cragg, Andrew J. Steele
Journal: Blood
Blood (2015) 125 (26): 4032–4041.
https://doi.org/10.1182/blood-2014-11-610329
Published: 2015
Includes: Supplemental data
Journal Articles

The Dual PI3K/mTOR Inhibitor PF-04691502 Induces Substantial Apoptosis in Chronic Lymphocytic Leukemia Cells in Vitro and Prolongs Survival in the Eµ-TCL1 Mouse Model

Free
Matthew D Blunt, PhD, Matthew J Carter, PhD, Marta Larrayoz, PhD, Maria Montserrat Aguilar, PhD, Sarah Murphy, Mark Reynolds, Thomas Tipton, Kerry Cox, Jonathan C Strefford, PhD, Freda K Stevenson, DPhil, Francesco Forconi, Graham Packham, PhD, Mark Cragg, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2014) 124 (21): 832.
https://doi.org/10.1182/blood.V124.21.832.832
Published: 2014
Journal Articles

IL-4 Exerts Opposing Effects on Surface-IgM and CXCR4 Mediated Signalling in Chronic Lymphocytic Leukaemia

Free
Maria Montserrat Aguilar, PhD, Matthew D Blunt, PhD, Jonathan C Strefford, PhD, Francesco Forconi, MD DM, PhD FRCPath, Mark Cragg, PhD, Freda K Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2014) 124 (21): 3299.
https://doi.org/10.1182/blood.V124.21.3299.3299
Published: 2014
Journal Articles

Modulation of B Cell Receptor Signalling By IL-4 In Chronic Lymphocytic Leukaemia

Free
Maria Aguilar-Hernandez, PhD, Matthew D Blunt, PhD, Jonathan C Strefford, Andrew Duncombe, MD, Francesco Forconi, MD, PhD, Freda K. Stevenson, DPhil, Graham K Packham, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2013) 122 (21): 4125.
https://doi.org/10.1182/blood.V122.21.4125.4125
Published: 2013