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Journal Articles

Genomic and Transcriptomic Characterization of IgM Multiple Myeloma Identifies a Pre-Germinal Center Plasma Cell Disorder with Immature B-Cell Transcription-Factor Signature

Abdul Hamid Bazarbachi, MD, Herve Avet-Loiseau, Zachary R Hunter, PhD, Raphael Szalat, Anil Aktas-Samur, PhD, Masood A. Shammas, PhD, Jill Corre, PharmD, PhD, Mariateresa Fulciniti, PhD, Kenneth Anderson, MD, Giovanni Parmigiani, PhD, Steven Treon, Mohamad Mohty, MD PhD, Mehmet K. Samur, PhD, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-138951

Published: 2020

Journal Articles

Base Excision Repair and Homologous Recombination Pathway Intermediates Drive Genomic Instability and Evolution in Myeloma

Chengcheng Liao, PhD MD, Srikanth Talluri, PhD, Subodh Kumar, PhD, Leutz Buon, Jiangning Zhao, PhD MD, Lakshmi B. Potluri, MBBS, Rao Prabhala, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 27–28.

https://doi.org/10.1182/blood-2020-141042

Published: 2020

Journal Articles

ABL1 Kinase Plays an Important Role in Spontaneous and Melphalan-Induced Genomic Instability in Multiple Myeloma: Potential Therapeutic Application

Subodh Kumar, PhD, Srikanth Talluri, PhD, Jiangning Zhao, PhD MD, Chengcheng Liao, PhD MD, Lakshmi B. Potluri, MBBS, Leutz Buon, Shidai Mu, Jialan Shi, MDPhD, Mychell Neptune-Buon, Chandraditya Chakraborty, PhD, Yu-Tzu Tai, PhD, Mehmet K. Samur, PhD, Mariateresa Fulciniti, PhD, Rao Prabhala, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 51.

https://doi.org/10.1182/blood-2020-142793

Published: 2020

Journal Articles

High-Dose Melphalan Significantly Increases Mutational Burden in Multiple Myeloma Cells at Relapse: Results from a Randomized Study in Multiple Myeloma

Mehmet K. Samur, PhD, Marco Roncador, MD MSc, Anil Aktas-Samur, PhD, Mariateresa Fulciniti, PhD, Abdul Hamid Bazarbachi, MD, Raphael Szalat, Masood A. Shammas, PhD, Adam S Sperling, MD PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Anjan Thakurta, Aurore Perrot, Jill Corre, PharmD, PhD, Philippe Moreau, MD, Kenneth Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-139014

Published: 2020

Journal Articles

Exploring POU2AF1 ( BOB-1 ) D ependency and Transcription Addiction in Multiple Myeloma

Zuzana Chyra, PhD, Mehmet Kemal Samur, PhD, Anil Aktas-Samur, PhD, Yan Xu, MD, Eugenio Morelli, MD, Sophia Adamia, PhD, Woojun D Park, Lin Charles, PhD, Masood A. Shammas, PhD, Roman Hajek, MD PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 49.

https://doi.org/10.1182/blood-2020-142587

Published: 2020

Journal Articles

Atpase Family AAA Domain-Containing Protein 2 (ATAD2) As a Novel Target in Multiple Myeloma

Lakshmi B. Potluri, MBBS, Srikanth Talluri, PhD, Leutz Buon, Mehmet K. Samur, PhD, Anil Aktas-Samur, PhD, Jialan Shi, MDPhD, Chandraditya Chakraborty, PhD, Subodh Kumar, PhD, Rao Prabhala, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 50.

https://doi.org/10.1182/blood-2020-140466

Published: 2020

Journal Articles

A High Throughput Functional Screen Identifies a Novel Apex Inhibitor: Augments Cytotoxicity While Significantly Decreasing Genomic Evolution in Myeloma

Srikanth Talluri, PhD, Jialan Shi, MDPhD, Mychell Neptune-Buon, Subodh Kumar, PhD, Lakshmi B. Potluri, MBBS, Nikhil C. Munshi, MD, Masood A. Shammas, PhD

Blood (2020) 136 (Supplement 1): 10–11.

https://doi.org/10.1182/blood-2020-139945

Published: 2020

Journal Articles

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Anil Aktas Samur, PhD, Tessa Han, Marco Roncador, MD MSc, Mariateresa Fulciniti, PhD, Raphael Szalat, Masood A. Shammas, PhD, Jill Corre, PharmD, PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Philippe Moreau, MD, Michel Attal, MD PhD, Anjan Thakurta, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 3055.

https://doi.org/10.1182/blood-2019-128521

Published: 2019

Journal Articles

Integrated Genomics and Functional Validation Identifies a Global Kinase Gene Signature Impacting Genome Stability in Myeloma

Subodh Kumar, PhD, Leutz Buon, Srikanth Talluri, PhD, Chengcheng Liao, MD PhD, Jialan Shi, MD PhD, Mychell Neptune, Chandraditya Chakraborty, PhD, Mehmet Kemal Samur, PhD, Rao Prabhala, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 363.

https://doi.org/10.1182/blood-2019-129069

Published: 2019

Journal Articles

Ongoing Spontaneous DNA Damage Creates Synthetic Lethality Targeted By Novel RAD51 Inhibitors in Multiple Myeloma

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Srikanth Talluri, PhD, Melinda Day, PhD, Mychell Neptune, Lakshmi B. Potluri, Chandraditya Chakraborty, PhD, Kevin Mills, PhD, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4378.

https://doi.org/10.1182/blood-2019-129121

Published: 2019

Journal Articles

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Zuzana Chyra, PhD, Maria Gkotzamanidou, MD PhD, Masood A. Shammas, PhD, Vassilis L. Souliotis, PhD, Yan Xu, MD, Mehmet K. Samur, PhD, Aaron B. Beeler, PhD, Roman Hajek, MD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4385.

https://doi.org/10.1182/blood-2019-130700

Published: 2019

Journal Articles

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

Chaitanya Yenumula, MD, Srikanth Talluri, PhD, Tommaso Perini, MD, Subodh Kumar, PhD, Jialan Shi, MD PhD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4467.

https://doi.org/10.1182/blood-2018-99-119346

Published: 2018

Journal Articles

PDZ Binding Kinase (PBK) - a Novel Gene Driving Genomic Evolution in Multiple Myeloma

Subodh Kumar, PhD, Leutz Buon, Srikanth Talluri, PhD, Jialan Shi, MD PhD, Hervé Avet-Loiseau, MD PhD, Mehmet Kemal Samur, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4474.

https://doi.org/10.1182/blood-2018-99-119186

Published: 2018

Journal Articles

Critical Role for Apobec and Its Interacting Partners in Mediating Mutations and Cell Growth in Multiple Myeloma (MM)

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Jialan Shi, MD PhD, Rao Prabhala, PhD, Hervé Avet-Loiseau, MD PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4462.

https://doi.org/10.1182/blood-2018-99-118441

Published: 2018

Journal Articles

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Chandraditya Chakraborty, PhD, Raphael Szalat, MD, Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Michael A Lopez, Masood A. Shammas, PhD, Paul Richardson, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Philippe Moreau, Michel Attal, Anjan Thakurta, PhD, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MDPhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 190.

https://doi.org/10.1182/blood-2018-190

Published: 2018

Journal Articles

Deciphering the Chronology of Copy Number Alterations in Multiple Myeloma (MM): What Comes First?

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, PhD, Florence Magrangeas, PhD, Masood A. Shammas, PhD, Mariateresa Fulciniti, PhD, Michel Attal, MD PhD, Philippe Moreau, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MD PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 3171.

https://doi.org/10.1182/blood-2018-99-120101

Published: 2018

Journal Articles

Bone Marrow Microenvironment Induces Genomic Instability and Enables Clonal Evolution in Multiple Myeloma

Tommaso Perini, MD, Raphael Szalat, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Michael A Lopez, BS, Puru Nanjappa, Kenneth Wen, BS, Na Li, MD, Yan Xu, MD, Yu-Tzu Tai, PhD, Masood A. Shammas, PhD, Kenneth C Anderson, MD, Fabio Ciceri, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4408.

https://doi.org/10.1182/blood.V130.Suppl_1.4408.4408

Published: 2017

Journal Articles

A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model

Jianhong Lin, MD MSc, Chun Yang, MD PhD, Li Xue, MD PhD, Zhenkui Wang, MD PhD, Yan Xu, MD, Mehmet Kemal Samur, PhD, Jianjun Zhao, MD, Ariel Kwart, BS, Masood A. Shammas, PhD, Xiaofeng Jiang, MD PhD, Wong Kwok-Kin, MD PhD, Ruben D. Carrasco, MD PhD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4410.

https://doi.org/10.1182/blood.V130.Suppl_1.4410.4410

Published: 2017

Journal Articles

PAK4 Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldestrostom Macroglobulinemia

Na Li, MD, Mariateresa Fulciniti, PhD, Michael A Lopez, BS, Tommaso Perini, MD, Raphael Szalat, MD, Subodh Kumar, PhD, Mehmet Kemal Samur, PhD, Lian Xu, Yan Xu, MD, William Senapedis, PhD, Erkan Baloglu, Stefania Oliva, MD, Masood A. Shammas, PhD, Zachary Hunter, PhD, Kenneth C Anderson, MD, Steven P Treon, MDPhDFRCP, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 648.

https://doi.org/10.1182/blood.V130.Suppl_1.648.648

Published: 2017

Journal Articles

Identifying Novel Genes Involved in Dysregulation of Homologous Recombination and Genomic Integrity in Myeloma

Subodh Kumar, PhD, Leutz Buon, Mehmet Kemal Samur, PhD, Puru Nanjappa, Srikanth Talluri, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 3050.

https://doi.org/10.1182/blood.V130.Suppl_1.3050.3050

Published: 2017

NARROW

Genomic and Transcriptomic Characterization of IgM Multiple Myeloma Identifies a Pre-Germinal Center Plasma Cell Disorder with Immature B-Cell Transcription-Factor Signature

Base Excision Repair and Homologous Recombination Pathway Intermediates Drive Genomic Instability and Evolution in Myeloma

ABL1 Kinase Plays an Important Role in Spontaneous and Melphalan-Induced Genomic Instability in Multiple Myeloma: Potential Therapeutic Application

High-Dose Melphalan Significantly Increases Mutational Burden in Multiple Myeloma Cells at Relapse: Results from a Randomized Study in Multiple Myeloma

Exploring POU2AF1 ( BOB-1 ) D ependency and Transcription Addiction in Multiple Myeloma

Atpase Family AAA Domain-Containing Protein 2 (ATAD2) As a Novel Target in Multiple Myeloma

A High Throughput Functional Screen Identifies a Novel Apex Inhibitor: Augments Cytotoxicity While Significantly Decreasing Genomic Evolution in Myeloma

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Integrated Genomics and Functional Validation Identifies a Global Kinase Gene Signature Impacting Genome Stability in Myeloma

Ongoing Spontaneous DNA Damage Creates Synthetic Lethality Targeted By Novel RAD51 Inhibitors in Multiple Myeloma

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

PDZ Binding Kinase (PBK) - a Novel Gene Driving Genomic Evolution in Multiple Myeloma

Critical Role for Apobec and Its Interacting Partners in Mediating Mutations and Cell Growth in Multiple Myeloma (MM)

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Deciphering the Chronology of Copy Number Alterations in Multiple Myeloma (MM): What Comes First?

Bone Marrow Microenvironment Induces Genomic Instability and Enables Clonal Evolution in Multiple Myeloma

A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model

PAK4 Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldestrostom Macroglobulinemia

Identifying Novel Genes Involved in Dysregulation of Homologous Recombination and Genomic Integrity in Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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