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Journal Articles

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel αIIb-specific αIIbβ3 antagonist

Robert Blue, M. Anna Kowalska, Jessica Hirsch, Marta Murcia, Christin A. Janczak, Amanda Harrington, Marketa Jirouskova, Jihong Li, Rudy Fuentes, Michael A. Thornton, Marta Filizola, Mortimer Poncz, Barry S. Coller

Blood (2009) 114 (1): 195–201.

https://doi.org/10.1182/blood-2008-08-169243

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

Structural and Therapeutic Insights from the Species Specificity and in Vivo Antithrombotic Activity of a Novel αIIb-Specific αIIbβ3 Antagonist

Robert Blue, M. Anna Kowalska, PhD, Marta Murcia, PhD, Christin A. Janczak, Marketa Jirouskova, PhD, Jihong Li, MD, Amanda Harrington, Rudy Fuentes, Michael A. Thornton, PhD, Marta Filizola, Mortimer Poncz, MD, Barry S. Coller, MD

Blood (2008) 112 (11): 256.

https://doi.org/10.1182/blood.V112.11.256.256

Published: 2008

Journal Articles

Application of high-throughput screening to identify a novel αIIb-specific small- molecule inhibitor of αIIbβ3-mediated platelet interaction with fibrinogen

Robert Blue, Marta Murcia, Charles Karan, Markéta Jiroušková, Barry S. Coller

Blood (2008) 111 (3): 1248–1256.

https://doi.org/10.1182/blood-2007-08-105544

Published: 2008

Includes: Multimedia, Supplemental data

Journal Articles

Generation of Megakaryocytes from Human Embryonic Stem Cells.

Deborah L. French, PhD, Marketa Jirouskova, PhD, Marion Kennedy, MS, Barry S. Coller, MD, Gordon Keller, PhD

Blood (2007) 110 (11): 1265.

https://doi.org/10.1182/blood.V110.11.1265.1265

Published: 2007

Journal Articles

Ligand density dramatically affects integrin αIIbβ3-mediated platelet signaling and spreading

Markéta Jiroušková, Jyoti K. Jaiswal, Barry S. Coller

Blood (2007) 109 (12): 5260–5269.

https://doi.org/10.1182/blood-2006-10-054015

Published: 2007

Includes: Multimedia, Supplemental data

Journal Articles

Outside-In Signaling by Integrin αIIbβ3 Is Dramatically Affected by the Density of Adsorbed Fibrinogen and Results in Differences in Calcium Mobilization, Integrin Engagement, and Platelet Morphology.

Marketa Jirouskova, PhD, Jyoti K. Jaiswal, PhD, Barry S. Coller, MD

Blood (2006) 108 (11): 1506.

https://doi.org/10.1182/blood.V108.11.1506.1506

Published: 2006

Journal Articles

Functional and Computational Analysis of the Role of the Adjacent to Metal Ion-Dependent Adhesion Site (ADMIDAS) of Integrin αIIbβ3.

Marketa Jirouskova, PhD, Marta Murcia, PhD, JiHong Li, MD, Marta Filizola, PhD, Barry S. Coller, MD

Blood (2006) 108 (11): 143.

https://doi.org/10.1182/blood.V108.11.143.143

Published: 2006

Journal Articles

Equilibrium and Non-Equilibrium Molecular Dynamics Simulations Provide Potential Mechanisms for the Loss of Ligand Binding to αIIbβ3 Mutants Affecting the Ligand-Induced Metal Binding Site (LIMBS).

Marta Murcia, PhD, Marketa Jirouskova, PhD, Jihong Li, MD, Barry S. Coller, MD, Filizola Marta, PhD

Blood (2006) 108 (11): 1805.

https://doi.org/10.1182/blood.V108.11.1805.1805

Published: 2006

Journal Articles

Hemostatic Factors Contribute to Tumor Cell Metastatic Potential by a Mechanism Linked to Natural Killer Cell Function.

Joseph S. Palumbo, MD, Kathryn E. Talmage, Jessica V. Massari, Christine M. La Jeunesse, Matthew J. Flick, Marketa Jirouskova, PhD, Jay L. Degen, PhD

Blood (2004) 104 (11): 690.

https://doi.org/10.1182/blood.V104.11.690.690

Published: 2004

Journal Articles

Differences in αIIbβ3 Biogenesis Dynamics between Umbilical Cord Blood-Derived Human Megakaryocyte-Like Cells and Transfected HEK293 Cells as Revealed by a Mathematical Model.

W. Beau Mitchell, MD, Marketa Jirouskova, PhD, JiHong Li, MD, Barry S. Coller, MD

Blood (2004) 104 (11): 1559.

https://doi.org/10.1182/blood.V104.11.1559.1559

Published: 2004

NARROW

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel αIIb-specific αIIbβ3 antagonist

Structural and Therapeutic Insights from the Species Specificity and in Vivo Antithrombotic Activity of a Novel αIIb-Specific αIIbβ3 Antagonist

Application of high-throughput screening to identify a novel αIIb-specific small- molecule inhibitor of αIIbβ3-mediated platelet interaction with fibrinogen

Generation of Megakaryocytes from Human Embryonic Stem Cells.

Ligand density dramatically affects integrin αIIbβ3-mediated platelet signaling and spreading

Outside-In Signaling by Integrin αIIbβ3 Is Dramatically Affected by the Density of Adsorbed Fibrinogen and Results in Differences in Calcium Mobilization, Integrin Engagement, and Platelet Morphology.

Functional and Computational Analysis of the Role of the Adjacent to Metal Ion-Dependent Adhesion Site (ADMIDAS) of Integrin αIIbβ3.

Equilibrium and Non-Equilibrium Molecular Dynamics Simulations Provide Potential Mechanisms for the Loss of Ligand Binding to αIIbβ3 Mutants Affecting the Ligand-Induced Metal Binding Site (LIMBS).

Hemostatic Factors Contribute to Tumor Cell Metastatic Potential by a Mechanism Linked to Natural Killer Cell Function.

Differences in αIIbβ3 Biogenesis Dynamics between Umbilical Cord Blood-Derived Human Megakaryocyte-Like Cells and Transfected HEK293 Cells as Revealed by a Mathematical Model.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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