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Manuela Tosi
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Journal Articles

Analysis of T-Cell Receptor Beta-Constant Region Expression for Rapid Assessment of T-Cell Clonality

Paul Maciocia, BSc, MBChB, MRCP, Margarida Neves, MSc, Shimobi Onuoha, PhD, Patrycja Wawrzyniecka, Giuseppe Gritti, Manuela Tosi, Alessia Moioli, Martin Pule, MD, Teresa Marafioti, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2867.
https://doi.org/10.1182/blood-2018-99-112569
Published: 2018
Journal Articles

Final Results of Northern Italy Leukemia Group (NILG) Trial 10/07 Combining Pediatric-Type Therapy with Minimal Residual Disease Study and Risk-Oriented Hematopoietic Cell Transplantation in Adult Acute Lymphoblastic Leukemia (ALL)

Renato Bassan, MD, Arianna Masciulli, PharmD, Tamara Intermesoli, MD, Orietta Spinelli, PhD, Manuela Tosi, PhD, Chiara Pavoni, MSc, Ernesta Audisio, MD, Giuseppe Rossi, MD, Monica Fumagalli, MD, Vincenzo Cassibba, MD, Daniele Mattei, MD, Claudio Romani, MD, Agostino Cortelezzi, MD, Fabio Ciceri, MD, Anna Maria Scattolin, MD, Umberto Vitolo, MD, Erika Borlenghi, MD, Sergio Cortelazzo, MD, Andrea Gallamini, MD, Lorella Depaoli, MD, Leonardo Campiotti, MD, Monica Tajana, MD, Monica Bocchia, MD, Antonella Vitale, MD, Marco Ladetto, MD, Eros Di Bona, MD, Elena Oldani, BiolSc, Alessandro Rambaldi, MD
Journal: Blood
Blood (2016) 128 (22): 176.
https://doi.org/10.1182/blood.V128.22.176.176
Published: 2016
Journal Articles

Levels of Minimal Residual Disease Prior to Transplant Influence Outcome of Adult Patients with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Federico Lussana, MD, Tamara Intermesoli, MD, Francesca Gianni, MD, Cristina Boschini, MSc, Arianna Masciulli, PhD MSc, Orietta Spinelli, PhD, Elena Oldani, BiolSc, Manuela Tosi, PhD, Rosa Maria Marfisi, MSc, Anna Grassi, MD, Margherita Parolini, MD, Ernesta Audisio, MD, Chiara Cattaneo, MD, Roberto Raimondi, MD, Emanuele Angelucci, MD, Irene Maria Cavattoni, MD, Anna Maria Scattolin, MD, Agostino Cortelezzi, MD, Francesco Mannelli, MD, Fabio Ciceri, MD, Daniele Mattei, MD, Erika Borlenghi, MD, Elisabetta Terruzzi, MD, Claudio Romani, MD, Renato Bassan, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2015) 126 (23): 4374.
https://doi.org/10.1182/blood.V126.23.4374.4374
Published: 2015
Journal Articles

Next Generation Sequencing (NGS) of TP53 Gene Allows to Identify a Very High Risk Group of Philadelphia Negative Acute Lymphoblastic Leukemia (ALL) Patients

Silvia Salmoiraghi, BiolSc, Greta Ubiali, BiolSc, Manuela Tosi, BiolSc, Barbara Peruta, BiolSc, Marie Lorena Guinea Montalvo, BiolSc, Elena Oldani, BiolSc, Cristina Boschini, MSc, Alexander Kohlmann, PhD, Sabina Chiaretti, Tamara Intermesoli, MD, Renato Bassan, MD, Orietta Spinelli, PhD, Alessandro Rambaldi
Journal: Blood
Blood (2014) 124 (21): 3796.
https://doi.org/10.1182/blood.V124.21.3796.3796
Published: 2014
Journal Articles

Phase II Randomized Trial Of Radiation-Free Central Nervous System (CNS) Prophylaxis Comparing Intrathecal Triple Therapy With Liposomal Cytarabine (DepoCyte ® ) In Adult Acute Lymphoblastic Leukemia (ALL)

Renato Bassan, MD, Arianna Masciulli, BiolSc, Tamara Intermesoli, MD, Ernesta Audisio, MD, Chiara Cattaneo, MD, Enrico Maria Pogliani, MD, Vincenzo Cassibba, MD, Daniele Mattei, MD, Claudio Romani, MD, Agostino Cortelezzi, MD, Consuelo Corti, MD, Anna Maria Scattolin, MD, Orietta Spinelli, BiolSC, Manuela Tosi, BiolSC, Margherita Parolini, MD, Filippo Marmont, MD, Erika Borlenghi, MD, Monica Fumagalli, MD, Sergio Cortelazzo, MD, Andrea Gallamini, MD, Rosa Maria Marfisi, Elena Oldani, BiolSC, Roberto Marchioli, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2013) 122 (21): 3901.
https://doi.org/10.1182/blood.V122.21.3901.3901
Published: 2013
Journal Articles

Early Response Dynamics Including Minimal Residual Disease (MRD) and Adherence to Risk/MRD-Oriented Therapy Are Major Outcome Determinants in Adult Ph-Negative Acute Lymphoblastic Leukemia (ALL).

Renato Bassan, MD, Orietta Spinelli, BiolSC, Elena Oldani, BiolSC, Manuela Tosi, BiolSC, Barbara Peruta, BiolSC, Erika Borlenghi, MD, Enrico Maria Pogliani, MD, Eros Di Bona, MD, Vincenzo Cassibba, MD, Anna Maria Scattolin, MD, Claudio Romani, MD, Fabio Ciceri, MD, Agostino Cortelezzi, MD, Giacomo Gianfaldoni, MD, Daniele Mattei, MD, Ernesta Audisio, MD, Tamara Intermesoli, Alessandro Rambaldi, MD
Journal: Blood
Blood (2012) 120 (21): 2573.
https://doi.org/10.1182/blood.V120.21.2573.2573
Published: 2012
Journal Articles

In Adult Acute Lymphoblastic Leukemia (ALL) Different Minimal Residual Disease (MRD) Levels Predict Clinical Outcome in All Patients and Response to Allogeneic/Autologous Transplantation in MRD-Positive Patients.

Renato Bassan, MD, Orietta Spinelli, BiolSC, Elena Oldani, BiolSC, Manuela Tosi, BiolSC, Barbara Peruta, BiolSC, Erika Borlenghi, MD, Enrico Maria Pogliani, MD, Eros Di Bona, MD, Vincenzo Cassibba, MD, Anna Maria Scattolin, MD, Claudio Romani, MD, Fabio Ciceri, MD, Agostino Cortelezzi, MD, Giacomo Gianfaldoni, MD, Daniele Mattei, MD, Ernesta Audisio, MD, Tamara Intermesoli, Alessandro Rambaldi, MD
Journal: Blood
Blood (2012) 120 (21): 2493.
https://doi.org/10.1182/blood.V120.21.2493.2493
Published: 2012
Journal Articles

In Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Imatinib (IM) and Chemotherapy in Combination Improve Remission Rate, Stem Cell Transplantation Rate and Long-Term Outcome

Tamara Intermesoli, MD, Chiara Cattaneo, MD, Enrico Maria Pogliani, MD, Eros Di Bona, MD, Claudio Romani, MD, Vincenzo Cassibba, MD, Agostino Cortelezzi, MD, Francesco Mannelli, MD, Fabio Ciceri, MD, Daniele Mattei, MD, Orietta Spinelli, BiolSC, Manuela Tosi, BiolSC, Elena Oldani, BiolSC, Alessandro Rambaldi, MD, Renato Bassan, MD
Journal: Blood
Blood (2012) 120 (21): 662.
https://doi.org/10.1182/blood.V120.21.662.662
Published: 2012
Journal Articles

Pediatric-Type Therapy Including Lineage-Targeted Methotrexate to Improve Early Minimal Residual Disease Response and Survival In Adult Acute Lymphoblastic Leukemia (ALL): Interim Analysis of Northern Italy Leukemia Group Study 10/07

Renato Bassan, Tamara Intermesoli, Arianna Masciulli, Giuseppe Rossi, Enrico Maria Pogliani, Orietta Spinelli, Giorgio Lambertenghi-Deliliers, Ernesta Audisio, Daniele Mattei, Fabio Ciceri, Vincenzo Cassibba, Claudio Romani, Eros Di Bona, Alessandro Levis, Manuela Tosi, Barbara Peruta, Margherita Parolini, Erika Borlenghi, Monica Fumagalli, Federica Delaini, Rosa Maria Marfisi, Elena Oldani, Roberto Marchioli, Alessandro Rambaldi
Journal: Blood
Blood (2010) 116 (21): 2131.
https://doi.org/10.1182/blood.V116.21.2131.2131
Published: 2010
Journal Articles

Improved Clinical Outcome of Adult Patients with Ph+ ALL After a Combined Imatinib-Chemotherapy Induction/Consolidation Program Followed by Allogeneic Hematopoietic Stem Cell Transplantation: Results From a Prospective Study of the Northern Italy Leukemia Group

Alessandro Rambaldi, Orietta Spinelli, Elena Oldani, Anna Grassi, Giuseppe Rossi, Enrico Maria Pogliani, Eros Di Bona, Emanuele Angelucci, Irene Cavattoni, Giorgio Lambertenghi-Deliliers, Francesco Mannelli, Alessandro Levis, Fabio Ciceri, M.D., Daniele Mattei, MD, Erika Borlenghi, Elisabetta Terruzzi, Claudio Borghero, Claudio Romani, Manuela Tosi, Adelaide Bussini, Tamara Intermesoli, Renato Bassan
Journal: Blood
Blood (2010) 116 (21): 682.
https://doi.org/10.1182/blood.V116.21.682.682
Published: 2010
Journal Articles

Short Chemotherapy-Phased Imatinib (IM) Pulses Improve Long-Term Outcome of Adult Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL).

Renato Bassan, MD, Giuseppe Rossi, MD, Enrico Maria Pogliani, MD, Eros Di Bona, MD, Emanuele Angelucci, MD, Irene Cavattoni, MD, Agostino Cortelezzi, MD, Giacomo Gianfaldoni, MD, Alessandro Levis, MD, Fabio Ciceri, MD, Daniele Mattei, MD, Erika Borlenghi, MD, Elisabetta Terruzzi, MD, Carlo Borghero, MD, Claudio Romani, MD, Orietta Spinelli, BSc, Manuela Tosi, BSc, Elena Oldani, BSc, Tamara Intermesoli, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2009) 114 (22): 2029.
https://doi.org/10.1182/blood.V114.22.2029.2029
Published: 2009
Journal Articles

Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)

Clinical Trials & Observations
Renato Bassan, Orietta Spinelli, Elena Oldani, Tamara Intermesoli, Manuela Tosi, Barbara Peruta, Giuseppe Rossi, Erika Borlenghi, Enrico M. Pogliani, Elisabetta Terruzzi, Pietro Fabris, Vincenzo Cassibba, Giorgio Lambertenghi-Deliliers, Agostino Cortelezzi, Alberto Bosi, Giacomo Gianfaldoni, Fabio Ciceri, Massimo Bernardi, Andrea Gallamini, Daniele Mattei, Eros Di Bona, Claudio Romani, Anna Maria Scattolin, Tiziano Barbui, Alessandro Rambaldi
Journal: Blood
Blood (2009) 113 (18): 4153–4162.
https://doi.org/10.1182/blood-2008-11-185132
Published: 2009
Includes: Supplemental data
Journal Articles

Minimal Residual Disease (MRD)-Oriented Therapy of Adult Acute Lymphoblastic Leukemia (ALL): Final Results of Northern Italy Leukemia Group Study 09/00.

Renato Bassan, MD, Orietta Spinelli, BSc, Elena Oldani, BSc, Tamara Intermesoli, MD, Manuela Tosi, BSc, Barbara Peruta, BSc, Vittoria Guerini, BSc, Giuseppe Rossi, MD, Enrico Pogliani, MD, Eros Di Bona, MD, Pietro Fabris, MD, Agostino Cortelezzi, MD, Teodoro Chisesi, MD, Emanuele Angelucci, MD, Franco Leoni, MD, Fabio Ciceri, MD, Daniele Mattei, MD, Tiziano Barbui, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2007) 110 (11): 3497.
https://doi.org/10.1182/blood.V110.11.3497.3497
Published: 2007
Journal Articles

Minimal Residual Disease (MRD) and Risk-Oriented Therapy in Adult Acute Lymphoblastic Leukemia (ALL).

Renato Bassan, MD, Orietta Spinelli, BSc, Elena Oldani, BSc, Tamara Intermesoli, MD, Manuela Tosi, BSc, Giuseppe Rossi, MD, Enrico M. Pogliani, MD, Emanuele Angelucci, MD, Pietro Fabris, MD, Giorgio Lambertenghi-Deliliers, MD, Paola Polistena, MD, Eros Di Bona, MD, Fabio Ciceri, MD, Franco Leoni, MD, Claudia Minotto, MD, Daniele Mattei, MD, Maurizio Musso, MD, Tiziano Barbui, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2005) 106 (11): 1836.
https://doi.org/10.1182/blood.V106.11.1836.1836
Published: 2005