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Journal Articles

Transcriptional Changes in Patients with CLL Starting Venetoclax Therapy Identifies Inflammatory and Adaptive Stress Responses

Layla M. Saleh, Maissa Mhibik, Jonathan Chen, Clare Sun, Christopher Pleyer, Adrian Wiestner
Journal: Blood
Blood (2023) 142 (Supplement 1): 4196.
https://doi.org/10.1182/blood-2023-190376
Published: 2023
Journal Articles

NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts

Deyi Zhang, Hailey M. Harris, Jonathan Chen, Jen Judy, Gabriella James, Aileen Kelly, Joel McIntosh, Austin Tenn-McClellan, Eileen Ambing, Ying Siow Tan, Hao Lu, Stefan Gajewski, Matthew C. Clifton, Stephanie Yung, Daniel W. Robbins, Mehdi Pirooznia, Sigrid S. Skånland, Erika Gaglione, Maissa Mhibik, Chingiz Underbayev, Inhye E. Ahn, Clare Sun, Sarah E. M. Herman, Mark Noviski, Adrian Wiestner
Journal: Blood
Blood (2023) 141 (13): 1584–1596.
https://doi.org/10.1182/blood.2022016934
Published: 2023
Includes: Supplemental data
Journal Articles

CD49d Expression Identifies a Biologically Distinct Subtype of Chronic Lymphocytic Leukemia with Inferior Progression Free Survival on BTK Inhibitor Therapy

Anfal Alsadhan, Jonathan Chen, Clare Sun, Chingiz Underbayev, Elena Bibikova, Tanja Nicole Hartmann, Maissa Mhibik, Adrian Wiestner
Journal: Blood
Blood (2022) 140 (Supplement 1): 6004–6005.
https://doi.org/10.1182/blood-2022-163370
Published: 2022
Journal Articles

BTK inhibitors, irrespective of ITK inhibition, increase efficacy of a CD19/CD3-bispecific antibody in CLL

Maissa Mhibik, Erika M. Gaglione, David Eik, Ellen K. Kendall, Amy Blackburn, Keyvan Keyvanfar, Maria Joao Baptista, Inhye E. Ahn, Clare Sun, Junpeng Qi, Christoph Rader, Adrian Wiestner
Journal: Blood
Blood (2021) 138 (19): 1843–1854.
https://doi.org/10.1182/blood.2020009686
Published: 2021
Includes: Supplemental data
Journal Articles

A CD19/CD3 Bispecific Antibody Induces Superior T Cell Responses Against Chronic Lymphocytic Leukemia When Combined with Ibrutinib

Maissa Mhibik, PhD, Erika M Gaglione, Amy Blackburn, Keyvan Keyvanfar, Clare Sun, MD, Inhye E Ahn, MD, Maria Joao Baptista, Junpeng Qi, PhD, Christoph Rader, PhD, Adrian Wiestner, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2861.
https://doi.org/10.1182/blood-2019-126186
Published: 2019