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Journal Articles

A Novel Cause of Type 1 VWD: Impaired Exocytosis of Weibel-Palade Bodies Due to Biallelic Mutations in Madd

Sophie Hordijk, Stijn A. Groten, Petra E. Bürgisser, Sebastiaan N.J. Laan, Georg-Christoph Korenke, Tomáš Honzik, Diane Beysen, Maartje van den Biggelaar, Tom Carter, Ruben Bierings

Blood (2024) 144 (Supplement 1): 431.

https://doi.org/10.1182/blood-2024-198653

Published: 2024

Journal Articles

Exploring Red Blood Cells As an Antigen Delivery System to Modulate the Immune Response Towards FVIII in Hemophilia a

Mariarosaria Miranda, Eelke Bradsma, Lotte Robben, Helena Van Dender, Floris Van Alphen, Karin Fijnvandraat, Maartje van den Biggelaar, Sebastien Lacroix-Desmazes, Robin van Bruggen, J. J. Voorberg

Blood (2024) 144 (Supplement 1): 5476.

https://doi.org/10.1182/blood-2024-203336

Published: 2024

Journal Articles

The Plasma Proteomic Landscape of Thrombotic Events across Multi-Center Cohorts

Iris charlotte Kreft, Eva Smit, Eleonora Camilleri, Louise Burggraaf, Nienke Van Rein, Bart Van Vlijmen, Anne-Marije Hulshof, Bas Van Bussel, Frank van Rosmalen, Tom van den Berg, Yvonne Henskens, Hugo Ten Cate, Jonathan Coutinho, Marieke Kruip, Jeroen Eikenboom, Arie Hoogendijk, Suzanne Cannegieter, Maartje Van Den Biggelaar

Blood (2023) 142 (Supplement 1): 5395.

https://doi.org/10.1182/blood-2023-185936

Published: 2023

Journal Articles

Characterization and Quantification of Von Willebrand Factor Proteoforms in Von Willebrand Disease Patients and Healthy Controls: Insights from the Win-Study

Iris charlotte Kreft, Tirsa T van Duijl, Calvin Van Kwawegen, Winny Phan, Margo Schuller, Carmen van Der Zwaan, Alexander Meijer, Ruben Bierings, Frank W.G. Leebeek, Maartje Van Den Biggelaar

Blood (2023) 142 (Supplement 1): 2606.

https://doi.org/10.1182/blood-2023-185987

Published: 2023

Journal Articles

Monitoring Changes in Plasma Proteome in AML Patients Receiving Blood Transfusion Products

Diana Muñoz Sandoval, Eva Smit, Iris charlotte Kreft, Carmen van Der Zwaan, Pieter Van Der Meer, Jan Voorberg, Paula F Ypma, Jean-Louis Kerkhoffs, Maartje Van Den Biggelaar

Blood (2023) 142 (Supplement 1): 2665.

https://doi.org/10.1182/blood-2023-180853

Published: 2023

Journal Articles

N-glycan–mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP

Bogac Ercig, Nuno A. G. Graça, Kadri Kangro, Tom Arfman, Kanin Wichapong, Johana Hrdinová, Paul Kaijen, Floris P. J. van Alphen, Maartje van den Biggelaar, Karen Vanhoorelbeke, Agnès Veyradier, Paul Coppo, Chris Reutelingsperger, Gerry A. F. Nicolaes, Andres Männik, Jan Voorberg

Blood (2021) 137 (19): 2694–2698.

https://doi.org/10.1182/blood.2020007972

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Factor VIII–driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry

Nadia Freato, Eduard H. T. M. Ebberink, Josse van Galen, Caroline Fribourg, Mariëtte Boon-Spijker, Floris P. J. van Alphen, Alexander B. Meijer, Maartje van den Biggelaar, Koen Mertens

Blood (2020) 136 (23): 2703–2714.

https://doi.org/10.1182/blood.2020005593

Published: 2020

Includes: Supplemental data

Journal Articles

Cultured Human Macrophages As a Model for Central Macrophages in Erythroblastic Islands

Esther Heideveld, MSc, Maartje van Den Biggelaar, PhD, Floris P. van Alphen, BSc, Marieke Von Lindern, PhD, Emile van den Akker, PhD

Blood (2016) 128 (22): 1248.

https://doi.org/10.1182/blood.V128.22.1248.1248

Published: 2016

Journal Articles

Cell-Surface Proteomics to Unravel Cytokine-Induced Endothelial Activation

Eelke Béguin, Bart van den Eshof, Koen Mertens, PhD, Alexander Meijer, PhD, Maartje van den Biggelaar

Blood (2015) 126 (23): 1039.

https://doi.org/10.1182/blood.V126.23.1039.1039

Published: 2015

Journal Articles

Regulation of Stimulated and Basal Release of Weibel-Palade Bodies By Syntaxin-3 Containing SNARE-Complexes

Dorothee Van Breevoort, PhD, Maryam Wahedi, Maaike Schillemans, Tom Carter, PhD, Stephan Huveneers, PhD, Maartje van den Biggelaar, PhD, J.J. Voorberg, PhD, Ruben Bierings, PhD

Blood (2014) 124 (21): 1440.

https://doi.org/10.1182/blood.V124.21.1440.1440

Published: 2014

Journal Articles

Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells

Maartje van den Biggelaar, Juan Ramon Hernández-Fernaud, Bart L. van den Eshof, Lisa J. Neilson, Alexander B. Meijer, Koen Mertens, Sara Zanivan

Blood (2014) 123 (12): e22–e36.

https://doi.org/10.1182/blood-2013-12-546036

Published: 2014

Includes: Supplemental data

Journal Articles

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis

Rachel T. McGrath, Maartje van den Biggelaar, Barry Byrne, Jamie M. O’Sullivan, Orla Rawley, Richard O’Kennedy, Jan Voorberg, Roger J. S. Preston, James S. O’Donnell

Blood (2013) 122 (25): 4107–4110.

https://doi.org/10.1182/blood-2013-04-496851

Published: 2013

Journal Articles

Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability

Esther Bloem, Msc, Henriet Meems, PhD, Maartje van den Biggelaar, PhD, Koen Mertens, PhD, Alexander B Meijer, PhD

Blood (2012) 120 (21): 3357.

https://doi.org/10.1182/blood.V120.21.3357.3357

Published: 2012

Journal Articles

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice

Aleksandra Wroblewska, Simon D. van Haren, Eszter Herczenik, Paul Kaijen, Aleksandra Ruminska, Sheng-Yu Jin, X. Long Zheng, Maartje van den Biggelaar, Anja ten Brinke, Alexander B. Meijer, Jan Voorberg

Blood (2012) 119 (22): 5294–5300.

https://doi.org/10.1182/blood-2011-11-391680

Published: 2012

Includes: Supplemental data

Journal Articles

Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies

Eveline A. M. Bouwens, Marjon J. Mourik, Maartje van den Biggelaar, Jeroen C. J. Eikenboom, Jan Voorberg, Karine M. Valentijn, Koen Mertens

Blood (2011) 118 (22): 5947–5956.

https://doi.org/10.1182/blood-2011-05-355354

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Specific N- and O-Linked Carbohydrate Structures Mediate Von Willebrand Factor Interaction with Galectins -1 and -3

Orla Rawley, Jamie O'Sullivan, Gudmundur Bergsson, PhD, Alain Chan, PhD, Rachel Therese McGrath, Maartje van den Biggelaar, Jan Voorberg, Vince Jenkins, PhD, James S O'Donnell, MD, PhD

Blood (2011) 118 (21): 2234.

https://doi.org/10.1182/blood.V118.21.2234.2234

Published: 2011

Journal Articles

The Role of Factor VIII C Domains in Sorting to Weibel-Palade Bodies

Eveline Bouwens, Maartje van den Biggelaar, Jan Voorberg, Koen Mertens, PhD

Blood (2011) 118 (21): 2241.

https://doi.org/10.1182/blood.V118.21.2241.2241

Published: 2011

Journal Articles

Co-Trafficking of Coagulation Factor VIII with Von Willebrand Factor Alters the Macromolecular Structure Inside Secretory Weibel-Palade Bodies

Eveline Bouwens, Marjon Mourik, Maartje van den Biggelaar, Jan Voorberg, Karine Valentijn, Koen Mertens, PhD

Blood (2010) 116 (21): 325.

https://doi.org/10.1182/blood.V116.21.325.325

Published: 2010

Journal Articles

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles

Maartje van den Biggelaar, Alexander B. Meijer, Jan Voorberg, Koen Mertens

Blood (2009) 113 (13): 3102–3109.

https://doi.org/10.1182/blood-2008-05-159699

Published: 2009

Journal Articles

Effective Factor VIII Endocytosis Is under Conformational Control of von Willebrand Factor.

Alexander B. Meijer, PhD, Sigrid D. Roosendaal, Bas de Laat, Ph.D., Maartje van den Biggelaar, Vincent Limburg, Carmen van der Zwaan, Kees W. Rodenburg, Ph.D., Koen Mertens, Ph.D.

Blood (2007) 110 (11): 1767.

https://doi.org/10.1182/blood.V110.11.1767.1767

Published: 2007

NARROW

A Novel Cause of Type 1 VWD: Impaired Exocytosis of Weibel-Palade Bodies Due to Biallelic Mutations in Madd

Exploring Red Blood Cells As an Antigen Delivery System to Modulate the Immune Response Towards FVIII in Hemophilia a

The Plasma Proteomic Landscape of Thrombotic Events across Multi-Center Cohorts

Characterization and Quantification of Von Willebrand Factor Proteoforms in Von Willebrand Disease Patients and Healthy Controls: Insights from the Win-Study

Monitoring Changes in Plasma Proteome in AML Patients Receiving Blood Transfusion Products

N-glycan–mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP

Factor VIII–driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry

Cultured Human Macrophages As a Model for Central Macrophages in Erythroblastic Islands

Cell-Surface Proteomics to Unravel Cytokine-Induced Endothelial Activation

Regulation of Stimulated and Basal Release of Weibel-Palade Bodies By Syntaxin-3 Containing SNARE-Complexes

Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis

Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice

Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies

Specific N- and O-Linked Carbohydrate Structures Mediate Von Willebrand Factor Interaction with Galectins -1 and -3

The Role of Factor VIII C Domains in Sorting to Weibel-Palade Bodies

Co-Trafficking of Coagulation Factor VIII with Von Willebrand Factor Alters the Macromolecular Structure Inside Secretory Weibel-Palade Bodies

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles

Effective Factor VIII Endocytosis Is under Conformational Control of von Willebrand Factor.

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American Society of Hematology

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American Society of Hematology

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