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Luca Melchiori
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Journal Articles

Potential Therapeutic Applications of Jak2 Inhibitors and Hif2a-ASO for the Treatment of β-Thalassemia Intermedia and Major

Carla Casu, Paraskevi Rea Oikonomidou, MD, Vania Lo Presti, Mariam Aghajan, PhD, Shuling Guo, PhD, Abdulmalik Osheiza, Luca Melchiori, Pedro Ramos, Stefano Rivella, PhD
Journal: Blood
Blood (2016) 128 (22): 1012.
https://doi.org/10.1182/blood.V128.22.1012.1012
Published: 2016
Journal Articles

Dicer is selectively important for the earliest stages of erythroid development

Brief Report
Natalija Buza-Vidas, Valeriu B. Cismasiu, Susan Moore, Adam J. Mead, Petter S. Woll, Michael Lutteropp, Luca Melchiori, Sidinh Luc, Tiphaine Bouriez-Jones, Deborah Atkinson, Donal O'Carroll, Sten Eirik W. Jacobsen, Claus Nerlov
Journal: Blood
Blood (2012) 120 (12): 2412–2416.
https://doi.org/10.1182/blood-2011-10-383653
Published: 2012
Includes: Supplemental data
Journal Articles

Potential Therapeutic Applications of Jak2 Inhibitors in Beta-Thalassemia and Sickle Cell Disease,

Carla Casu, PhD, Pedro Ramos, PhD, Luca Melchiori, PhD, Ella Guy, Eliezer A. Rachmilewitz, Patricia Giardina, MD, Robert W Grady, PhD, Maria de Sousa, MD, PhD, Stefano Rivella, PhD
Journal: Blood
Blood (2011) 118 (21): 3187.
https://doi.org/10.1182/blood.V118.21.3187.3187
Published: 2011
Journal Articles

Use of Jak2 Inhibitors to Limit Ineffective Erythropoiesis and Iron Absorption in Mice Affected by β-Thalassemia and Other Disorders of Red Cell Production.

Luca Melchiori, Sara Gardenghi, PhD, Ella C. Guy, Eliezer Rachmilewitz, M.D, Patricia J Giardina, MD, Robert W. Grady, PhD, Mohandas Narla, DSc, Xiuli An, MD, PhD, Stefano Rivella, PhD
Journal: Blood
Blood (2009) 114 (22): 2020.
https://doi.org/10.1182/blood.V114.22.2020.2020
Published: 2009
Journal Articles

Potential Use of Jak2 Inhibitors to Limit Ineffective Erythropoiesis and Reverse Splenomegaly in β-Thalassemia.

Luca Melchiori, Ella Guy, Ilaria Libani, Ph.D, Raffaella Schirò, MD, Ph.D, Pedro Ramos, Laura Breda, Ph.D, Amy Chadburn, MD, Yi-Fang Liu, Maria De Sousa, MD, Eliezer Rachmilewitz, M.D, Patricia J Giardina, MD, Robert W Grady, Ph.D, Stefano Rivella, Ph.D
Journal: Blood
Blood (2008) 112 (11): 1877.
https://doi.org/10.1182/blood.V112.11.1877.1877
Published: 2008
Journal Articles

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia

Ilaria V. Libani, Ella C. Guy, Luca Melchiori, Raffaella Schiro, Pedro Ramos, Laura Breda, Thomas Scholzen, Amy Chadburn, YiFang Liu, Margrit Kernbach, Bettina Baron-Lühr, Matteo Porotto, Maria de Sousa, Eliezer A. Rachmilewitz, John D. Hood, M. Domenica Cappellini, Patricia J. Giardina, Robert W. Grady, Johannes Gerdes, Stefano Rivella
Journal: Blood
Blood (2008) 112 (3): 875–885.
https://doi.org/10.1182/blood-2007-12-126938
Published: 2008
Includes: Supplemental data
Journal Articles

Accelerated Proliferation and Limited Differentiation, Mediated through Jak2, Exacerbate Ineffective Erythropoiesis in β-Thalassemia.

Ella Guy, Ilaria Libani, PhD, Luca Melchiori, Thomas Scholzen, PhD, Raffaella Schiro, MD, Pedro Ramos, Margrit Kernbach, Bettina Baron-Luehr, Laura Breda, PhD, Matteo Porotto, PhD, Maria de Sousa, MD, Maria Domenica Cappellini, MD, Patricia J. Giardina, MD, Robert W. Grady, PhD, Johannes Gerdes, PhD, Stefano Rivella, PhD
Journal: Blood
Blood (2007) 110 (11): 275.
https://doi.org/10.1182/blood.V110.11.275.275
Published: 2007