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Lindsay D Smith
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Journal Articles

Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment

Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A. C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering
Journal: Blood
Blood (2022) 140 (6): 630–643.
https://doi.org/10.1182/blood.2021013990
Published: 2022
Includes: Supplemental data
Journal Articles

Regulation and Impact of BCR Induced Autophagy in Chronic Lymphocytic Leukemia

Lindsay D Smith, PhD, Laura I Karydis, PhD, Margaret Ashton-Key, MD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Graham Packham, PhD, Mark Cragg, PhD, David A Tumbarello, PhD, Matthew D Blunt, PhD, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Steele, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1717.
https://doi.org/10.1182/blood.V130.Suppl_1.1717.1717
Published: 2017
Journal Articles

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Matthew D Blunt, PhD, Lindsay D Smith, PhD, Adam Linley, PhD BSc, Jonathan C Strefford, PhD, Peter Johnson, Francesco Forconi, MD DM, PhD FRCPath, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4290.
https://doi.org/10.1182/blood.V130.Suppl_1.4290.4290
Published: 2017
Journal Articles

Regulation of B-Cell Receptor Signalling By the Tumour Microenvironment in Chronic Lymphocytic Leukemia (CLL) and Its Impact on Adhesion and miRNA Expression

Matthew D Blunt, PhD, Rachel Dobson, BSc(Hons), Lindsay D Smith, PhD, Jonathan C. Strefford, Pamela B. Conley, PhD, Anjali Pandey, PhD, Andrew J Davies, FRCP PhD, Peter M Johnson, MA, MD, Graham Packham, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath, Greg P Coffey, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2016) 128 (22): 351.
https://doi.org/10.1182/blood.V128.22.351.351
Published: 2016
Journal Articles

Chemical Activation of the SHIP1 Inositol Lipid Phosphatase: A Novel Therapeutic Strategy to Suppress B-Cell Receptor Signaling and CXCR4 Expression in Malignant Human B Cells

Graham Packham, PhD, Beatriz Valle-Argos, Elizabeth Lemm, Lindsay D Smith, PhD, Nicola J Weston-Bell, PhD, Yohannes Gebreselassie, Andrew J Steele, PhD, Freda K Stevenson, Mark S Cragg, PhD, Francesco Forconi, MD DM, PhD FRCPath, Jennifer Cross, Curtis Harwig, Lloyd Mackenzie
Journal: Blood
Blood (2016) 128 (22): 2037.
https://doi.org/10.1182/blood.V128.22.2037.2037
Published: 2016
Journal Articles

IL-4 enhances expression and function of surface IgM in CLL cells

Maria M. Aguilar-Hernandez, Matthew D. Blunt, Rachel Dobson, Alison Yeomans, Stephen Thirdborough, Marta Larrayoz, Lindsay D. Smith, Adam Linley, Jonathan C. Strefford, Andrew Davies, Peter M. W. Johnson, Natalia Savelyeva, Mark S. Cragg, Francesco Forconi, Graham Packham, Freda K. Stevenson, Andrew J. Steele
Journal: Blood
Blood (2016) 127 (24): 3015–3025.
https://doi.org/10.1182/blood-2015-11-682906
Published: 2016
Includes: Supplemental data
Journal Articles

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

Matthew D. Blunt, Matthew J. Carter, Marta Larrayoz, Lindsay D. Smith, Maria Aguilar-Hernandez, Kerry L. Cox, Thomas Tipton, Mark Reynolds, Sarah Murphy, Elizabeth Lemm, Samantha Dias, Andrew Duncombe, Jonathan C. Strefford, Peter W. M. Johnson, Francesco Forconi, Freda K. Stevenson, Graham Packham, Mark S. Cragg, Andrew J. Steele
Journal: Blood
Blood (2015) 125 (26): 4032–4041.
https://doi.org/10.1182/blood-2014-11-610329
Published: 2015
Includes: Supplemental data