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Lars Bullinger, MD
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Journal Articles

Clonally Expanded Bone Marrow T Cells Show Effector Differentiation and Rarely Recognize Disease-Associated Antigens in Multiple Myeloma

Carlotta Welters, Meng-Tung Hsu, Christian Alexander Stein, Livius Penter, María Fernanda Lammoglia Cobo, Kerstin Dietze, Eric Blanc, Dieter Beule, Lars Bullinger, MD, Julian Strobel, Holger Hackstein, Armin Gerbitz, MDPhD, Klaus Dornmair, Thomas Blankenstein, Leo Hansmann
Journal: Blood
Blood (2020) 136 (Supplement 1): 7.
https://doi.org/10.1182/blood-2020-136991
Published: 2020
Journal Articles

Mutational Landscape of Relapsed Core-Binding Factor Acute Myeloid Leukemia (CBF-AML)

Anna Dolnik, Nikolaus Jahn, MD, Eric Sträng, PhD, Sibylle Cocciardi, PhD, Frank G. Rücker, MD, Ekaterina Panina, MD, Tamara J. Blätte, PhD, Julia Katharina Herzig, PhD, Andrea Corbacioglu, PhD, Daniela Weber, MSc, Anika Schrade, PhD, Verena I Gaidzik, MD, Sabrina Skambraks, Katharina S. Götze, Michael Luebbert, MD PhD, Walter Fiedler, MD, Thomas Schroeder, Corinna Hahn, Felicitas Thol, Michael Heuser, Arnold Ganser, Peter Paschka, MD, Hartmut Döhner, Konstanze Döhner, Lars Bullinger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-142392
Published: 2020
Journal Articles

Integration of Hi-C and Nanopore Sequencing for Structural Variant Analysis in AML with a Complex Karyotype: (Chromothripsis)²

Marius-Konstantin Klever, Eric Sträng, PhD, Julius Jungnitsch, Uirá Souto Melo, Sara Hetzel, Anna Dolnik, Robert Schöpflin, Jens F. Schrezenmeier, Olga Blau, Jörg Westermann, Konstanze Döhner, Hubert Schrezenmeier, Malte Spielmann, Alexander Meissner, PhD, Stefan Mundlos, Lars Bullinger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-133787
Published: 2020
Journal Articles

COVID-19: B-Cell Depletion and Sepsis Related Changes in Bone Marrow and Spleen

Jana Ihlow, MD, Ann-Christin von-Bruenneck, MD, Edward Georg Michaelis, MD, Selina Greuel, MD, Verena Heynol, Annika Lehmann, Dr., Helena Radbruch, MD, Jenny Meinhardt, MD, Victor Max Corman, MD, Florian Miller, MD, Hermann Herbst, MDFRCPath, Jörg Westermann, Lars Bullinger, MD, David Horst, MD, Sefer Elezkurtaj, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46.
https://doi.org/10.1182/blood-2020-136199
Published: 2020
Journal Articles

Polatuzumab Vedotin in Relapsed and Refractory (r/r) Large B-Cell Lymphoma (LBCL): Real-World Data of the German National Compassionate Use Program (CUP)

Nora Liebers, MD, Johannes Duell, MD, Daniel Nörenberg, MD, Eva Kaebisch, MD, Andrea Kerkhoff, MD, Fabian Acker, MD, Stephan Fuhrmann, MD, Corinna Leng, MD PhD, Manfred Welslau, MD, Jens Chemnitz, MD, Jan Moritz Middeke, MD, Thomas Weber, MD, Ralf Ulrich Trappe, MD, Roald Pfannes, MD, Ruediger Liersch, MD, Christian Spoer, MD, Niklas Gebauer, MD, Stefan Fuxius, MD, Léandra Caillé, Christiane Pott, MD PhD, Christian Koenecke, MD, Udo Holtick, Thomas Geer, MD, Ulrich Keller, MD, Rainer Claus, MD, Dimitrios Mougiakakos, MD, Stephanie Mayer, MD, Andreas Hüttmann, MD, Arne Trummer, MD, Gerald Wulf, MD, Uta Brunnberg, MD, Lars Bullinger, MD, Georg Hess, MD, Carsten Mueller-Tidow, MD, Bertram Glass, MD, Georg Lenz, Peter Dreger, MD, Sascha Dietrich, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–13.
https://doi.org/10.1182/blood-2020-136539
Published: 2020
Journal Articles

Next-Generation Sequencing (NGS)-Based Measurable Residual Disease (MRD) Monitoring in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication ( FLT3 -ITD + AML) Treated with Additional Midostaurin

Julia K. Herzig, PhD, Frank G. Rücker, MD, Laura K. Schmalbrock, MD, Tamara J. Blätte, PhD, Daniela Weber, MSc, Sabrina Skambraks, Silke Kapp-Schwoerer, MD, Andrea Corbacioglu, PhD, Verena I Gaidzik, MD, Peter Paschka, MD, Ekaterina Panina, MD, Nikolaus Jahn, MD, Anika Schrade, PhD, Frauke Theis, MD, Sibylle Cocciardi, PhD, Walter Fiedler, MD, Helmut R. Salih, Gerald Wulf, MD, Hans Salwender, MD, Thomas Schroeder, Katharina S. Götze, Thomas Kindler, MD, Michael Luebbert, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Lars Bullinger, MD, Konstanze Döhner
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-137568
Published: 2020
Journal Articles

AML: Negative Prognostic Impact of Early Blast Persistence Can be Overcome By Subsequent Remission Induction

Jana Ihlow, MD, Sophia Gross, Leonie Busack, Alma Herneth, Igor-Wolfgang Blau, MD PhD, Ioannis Anagnostopoulos, MD, Michaela Schwarz, MD, Anne Floercken, MD, Lars Bullinger, MD, Jörg Westermann, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1324.
https://doi.org/10.1182/blood-2019-127174
Published: 2019
Journal Articles

Deregulated Expression of Circular RNAs in Acute Myeloid Leukemia

Susanne Lux, MSc, Tamara J. Blätte, MSc, Sibylle Cocciardi, MSc, Klaus Schwarz, MD, Hartmut Döhner, MD, Konstanze Döhner, MD, Lars Bullinger, MD, Anna Dolnik, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3894.
https://doi.org/10.1182/blood-2018-99-113333
Published: 2018
Journal Articles

MiR-193a Is a Negative Regulator of Hematopoietic Stem Cells and Promotes Anti-Leukemic Effects in Acute Myeloid Leukemia

Kathrin Krowiorz, Raj Bhayadia, Razan Jammal, Caroline Pabst, Nicole Pochert, MSc, Christoph Rueß, MSc, Christina Miller, Konstanze Döhner, MD, Tobias Maetzig, PhD, Hartmut Döhner, MD, Lars Bullinger, MD, Stephan Emmrich, PhD MSc, Dirk Heckl, PhD, Vera Martins, Reinhild Rösler, PhD, Sebastian Wiese, PhD, R. Keith Humphries, MD PhD, Arefeh Rouhi, PhD, Jan-Henning Klusmann, Florian Kuchenbauer, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2627.
https://doi.org/10.1182/blood-2018-99-116256
Published: 2018
Journal Articles

Characteristics of DNMT3A- R882 Mutation in AML

Olga Blau, MD PhD, Franziska Behrenbeck, Mirgul Bayanova, MD, Igor-Wolfgang Blau, MD PhD, Lars Bullinger, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5263.
https://doi.org/10.1182/blood-2018-99-116652
Published: 2018
Journal Articles

Prognostic Impact of Insertion Site in Acute Myeloid Leukemia (AML) with FLT3 Internal Tandem Duplication: Results from the Ratify Study (Alliance 10603)

Frank G. Rücker, MD, Ling Du, PhD, Tamara J. Blätte, MSc, Axel Benner, Julia Krzykalla, MSc, Insa Gathmann, Richard A. Larson, MD, Francesco Lo-Coco, MD, Sergio Amadori, MD, Thomas W Prior, MD, Joseph M. Brandwein, MD, Frederick R. Appelbaum, MD, Bruno C. Medeiros, MD, Martin S. Tallman, MD, Michelle Geddes, MD, Jorge Sierra, MD, Eva Tiecke, PhD, Celine Pallaud, PhD, Miguel A. Sanz, MD, Theo M de Witte, MD, Dietger Niederwieser, MD, Gerhard Ehninger, MD, Michael Heuser, MD, Arnold Ganser, MD, Lars Bullinger, MD, Clara D. Bloomfield, MD, Richard M. Stone, MD, Hartmut Döhner, MD, Christian Thiede, MD, Konstanze Dohner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 435.
https://doi.org/10.1182/blood-2018-99-116149
Published: 2018
Journal Articles

DNMT3A expression Analysis in AML

Yubin Xing, MD, Franziska Behrenbeck, Mirgul Bayanova, MD, Igor Blau, MD PhD, Lars Bullinger, MD, Olga Blau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5276.
https://doi.org/10.1182/blood-2018-99-113626
Published: 2018
Journal Articles

A Novel Predictor of Response to Gemtuzumab Ozogamicin Therapy in AML Provides Strategies for Sensitization of Leukemia Stem Cells in Individual Patients

Stanley W.K. Ng, Schoof E Erwin, Amanda Mitchell, PhD, Mark D. Minden, MD PhD, Lars Bullinger, MD, Hartmut Döhner, MD, Hervé Dombret, Claude Preudhomme, Meyling Cheok, BSPharm, PhD, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2765.
https://doi.org/10.1182/blood-2018-99-114275
Published: 2018
Journal Articles

Identification of Genetic Pathways Controlling Resistance to Standard Combination Chemotherapy in Acute Myeloid Leukemia

Victoria Y Ling, MBBS, William Godfrey, Sebastien Jacquelin, PhD, Jasmin Straube, PhD, Leanne T Cooper, Claudia Bruedigam, PhD, Siok-Keen Tey, MBBS PhDFRACP FRCPA, Lars Bullinger, MD, Marco J Herold, Megan Bywater, PhD, Steven W. Lane, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2771.
https://doi.org/10.1182/blood-2018-99-115729
Published: 2018
Journal Articles

Expression of PD-L1 in Leukemic Progenitor Cells Defines NPM1 Mutated AML As a Potential Subgroup for PD1/PD-L1 Directed Immunotherapy

Jochen Greiner, Vanessa Schneider, Dr. rer. nat., Hubert Schrezenmeier, MD, Markus Wiesneth, MD, Lars Bullinger, MD, Hartmut Döhner, MD, Susanne Hofmann, MD, Marlies Götz
Journal: Blood
Blood (2018) 132 (Supplement 1): 2734.
https://doi.org/10.1182/blood-2018-99-111458
Published: 2018
Journal Articles

NGS-Based Monitoring of Measurable Residual Disease in FLT3 -ITD Positive Acute Myeloid Leukemia

Tamara J. Blätte, MSc, Laura K. Schmalbrock, MD, Sabrina Skambraks, Sibylle Cocciardi, MSc, Anna Dolnik, PhD, Konstanze Döhner, MD, Lars Bullinger, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2778.
https://doi.org/10.1182/blood-2018-99-113382
Published: 2018
Journal Articles

Assessment of the Genomic Landscape of Intermediate Risk Acute Myeloid Leukemia As Defined By 2010 ELN Risk Classification

Ekaterina Panina, MD, Frank G. Rücker, MD, Lars Bullinger, MD, Anna Dolnik, PhD, Julia Herzig, PhD, Tamara J. Blätte, MSc, Verena I. Gaidzik, MD, Peter Paschka, MD, Maria-Veronica Teleanu, MD, Nikolaus Jahn, MD, Laura K. Schmalbrock, MD, Daniela Weber, MSc, Lena Kubanek, Thomas Kindler, MD, Jörg Westermann, MD, Michael Lubbert, MD PhD, Helmut R. Salih, MD, Felicitas Thol, MD, Michael Heuser, MD, Arnold Ganser, MD, Hartmut Döhner, MD, Konstanze Döhner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 994.
https://doi.org/10.1182/blood-2018-99-114671
Published: 2018
Journal Articles

Monitoring of FLT3 Phosphorylation and FLT3 Ligand Levels in Patients with FLT3 -ITD Mutated Acute Myeloid Leukemia (AML) Treated with Midostaurin within the AMLSG 16-10 Trial of the German-Austrian Study Group

Frauke Theis, Daniela Weber, MSc, Frank G. Rücker, MD, Peter Paschka, MD, Verena I. Gaidzik, MD, Felicitas Thol, MD, Michael Heuser, MD, Walter Fiedler, MD, Gerald Wulf, MD, Michael Lübbert, MD PhD, Helmut R. Salih, MD, Thomas Michael Schroeder, MD PhD, Katharina S. Götze, MD, Hans Jürgen Salwender, MD, Thomas Kindler, MD, Heinz-August Horst, MD, Mark Ringhoffer, MD, Dominik Wolf‎, MD, Jürgen Krauter, MD, Richard F. Schlenk, MD, Lars Bullinger, MD, Arnold Ganser, MD, Hartmut Döhner, MD, Konstanze Döhner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1501.
https://doi.org/10.1182/blood-2018-99-114588
Published: 2018
Journal Articles

MYC Pathway Activation Is Frequently Observed in Treatment-Naive CLL and Defines a Subgroup with Particular Benefit from the Addition of Rituximab to Chemotherapy

Johannes Bloehdorn, MD, Julia Krzykalla, MSc, Billy Michael Chelliah Jebaraj, PhD, Karlheinz Holzmann, Dr. rer. nat., Jasmin Bahlo, PhD, Sandra Robrecht, PhD, Kathryn Humphrey, Michael Wenger, Eugen Tausch, MD, Christof Schneider, MD, Lars Bullinger, MD, Kirsten Fischer, MD, Michael Hallek, MD, Daniel Mertens, Axel Benner, Hartmut Döhner, MD, Stephan Stilgenbauer
Journal: Blood
Blood (2018) 132 (Supplement 1): 1866.
https://doi.org/10.1182/blood-2018-99-116937
Published: 2018
Journal Articles

BRCA1/2 Containing Complex 3 ( BRCC36 ) Is Recurrently Mutated in AML with t(8;21) and Associated with Increased Sensitivity to Chemotherapy through Impairment of the DNA Damage Repair Pathway

Tatjana Meyer, MSc, Nikolaus Jahn, MD, Anna Dolnik, PhD, Peter Paschka, MD, Verena I. Gaidzik, MD, Daniela Weber, MSc, Lars Bullinger, MD, Hartmut Döhner, MD, Konstanze Döhner, MD, Jan Kroenke, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1487.
https://doi.org/10.1182/blood-2018-99-114143
Published: 2018