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Journal Articles

A Mouse Homolog of Mutant Wasp Responsible for X-Linked Neutropenia Causes Reduced Myeloid Progenitor Activity but Rather Increased Neutrophil Compartment in Bone Marrow

Masahiro Ikeda, Muneyoshi Futami, MD PhD, Bidisha Chanda, MD PhD, Masayuki Kobayashi, MD PhD, Kiyoko Izawa, PhD, Arinobu Tojo, MD PhD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-139059

Published: 2020

Journal Articles

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Kiyoko Izawa, PhD, Tomoya Kakegawa, Master, Masayuki Yamamoto, MD PhD, Arinobu Tojo, MD PhD

Blood (2014) 124 (21): 1567.

https://doi.org/10.1182/blood.V124.21.1567.1567

Published: 2014

Journal Articles

In vivo leukemogenic potential of an interleukin 7 receptor α chain mutant in hematopoietic stem and progenitor cells

Kazuaki Yokoyama, Nozomi Yokoyama, Kiyoko Izawa, Ai Kotani, Akira Harashima, Katsuto Hozumi, Arinobu Tojo

Blood (2013) 122 (26): 4259–4263.

https://doi.org/10.1182/blood-2012-08-451278

Published: 2013

Includes: Supplemental data

Journal Articles

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

Kiyoko Izawa, PhD, Masayuki Yamamoto, MD, PhD, Arinobu Tojo, MD, PhD.

Blood (2013) 122 (21): 2418.

https://doi.org/10.1182/blood.V122.21.2418.2418

Published: 2013

Journal Articles

Unique Role of mTOR Inhibitor, Everolimus in Inducible Regulatory T Cells

Tokiko Nagamura-Inoue, MD, PhD., Yuki Yamamoto, MT., Seiichiro Kobayashi, MD, PhD, Kazuo Ogami, Kiyoko Izawa, PhD, Miki Yuzawa, MT., Hajime Tsunoda, MD, PhD., Arinobu Tojo, MD, PhD.

Blood (2012) 120 (21): 4349.

https://doi.org/10.1182/blood.V120.21.4349.4349

Published: 2012

Journal Articles

The Significance of mTOR Inhibitor, Everolimus in TGF-β-Induced Regulatory T cells from Cord Blood

Tokiko Nagamura-Inoue, Seiichiro Kobayashi, MD, PhD, Kazuo Ogami, Yuki Yamamoto, Kiyoko Izawa, PhD, Arinobu Tojo, MD, PhD

Blood (2011) 118 (21): 2180.

https://doi.org/10.1182/blood.V118.21.2180.2180

Published: 2011

Journal Articles

The in Vitro and In Vivo Oncogenic Activity of Homodimeric Mutant of Interleukin-7 Receptor a Chain (IL7Rα) Highlights the Significance of the IL7Rα/Jak1 Pathway in T-Cell Acute Lymphoblastic Leukemia

Kazuaki Yokoyama, MD, Nozomi Yokoyama, Kiyoko Izawa, PhD, Ai Kotani, MD, PhD, Ratanakanit Harnprasopwat, PhD, Akira Harashima, MD, PhD, Seiichiro Kobayashi, MD, PhD, Arinobu Tojo, MD, PhD

Blood (2011) 118 (21): 73.

https://doi.org/10.1182/blood.V118.21.73.73

Published: 2011

Journal Articles

Bcr-Abl Impairs T Cell Development From Murine Induced Pluripotent Stem Cells and Hematopoietic Stem Cells; A Partial Explanation for the Concept That Ph+ Clone Never Involves T Cell Lineage in CML,

Bidisha Chanda, MBBS, Kiyoko Izawa, PhD, Ratanakanit Harnprasopwat, PhD, Keisuke Takahashi, Seiichiro Kobayashi, MD, PhD, Yumi Kanegae, PhD, Izumu Saito, PhD, Arinobu Tojo, MD, PhD

Blood (2011) 118 (21): 3748.

https://doi.org/10.1182/blood.V118.21.3748.3748

Published: 2011

Journal Articles

Hormone-Conditional Activation of Bcr-Abl Kinase Highlights Stat5 Anti-Apoptotic Pathway Prior to Promoting Cell Growth.

Ratanakanit Harnprasopwat, Naoyuki Takahashi, MD, PhD, Seiichiro Kobayashi, MD, PhD, Kazuaki Yokoyama, MD, Kiyoko Izawa, PhD, Ai Kotani, MD, PhD, Toshio Kitamura, MD, PhD, Arinobu Tojo, MD, PhD

Blood (2010) 116 (21): 3380.

https://doi.org/10.1182/blood.V116.21.3380.3380

Published: 2010

Journal Articles

Leukemogenic Fusion Gene (p190 BCR-ABL) Transduction Into Hematopoietic Stem/Progenitor Cells In the Common Marmoset

Yamin Tian, MD, Yan Dong, MD, PhD, Seiichiro Kobayashi, MD, PhD, Manabu Ozawa, PhD, Kiyoko Izawa, PhD, Yuansong Bai, MD, PhD, Yasushi Soda, MD, PhD, Erika Sasaki, PhD, Toshio Itoh, PhD, Naoki Oyaizu, MD, PhD, Satoshi Takahashi, Arinobu Tojo, MD, PhD, Chieko Kai, PhD, Kenzaburo Tani, MD, PhD

Blood (2010) 116 (21): 4323.

https://doi.org/10.1182/blood.V116.21.4323.4323

Published: 2010

Journal Articles

Conditional Activation of Bcr-Abl Kinase Delineates Time-Dependent Transforming Events in Hematopoietic Cells.

Ratanakanit Harnprasopwat, Kiyoko Izawa, Seiichiro Kobayashi, Ai Kotani, Naoyuki Takahashi, Arinobu Tojo, MD, PhD

Blood (2009) 114 (22): 2162.

https://doi.org/10.1182/blood.V114.22.2162.2162

Published: 2009

Journal Articles

Large Scale Selective Ex Vivo Expansion of CD4 + CD25 + FOXP3 + Regulatory T Cells from Peripheral Blood.

Tokiko Nagamura-Inoue, MD, PhD, Kazuo Ogami, Kazuaki Yokoyama, Kiyoko Izawa, Seiichiro Kobayashi, Shin Nakayama, Ikuo Ishige, Yusuke Inoue, Jun Ooi, Kaoru Uchimaru, Satoshi Takahashi, Arinobu Tojo

Blood (2008) 112 (11): 2344.

https://doi.org/10.1182/blood.V112.11.2344.2344

Published: 2008

Journal Articles

Development of a Unique In Vitro and In Vivo Model System of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph-ALL) with Emphasis on Cell to Cell Interaction.

Arinobu Tojo, MD, PhD, Kiyoko Izawa, PhD, Rieko Sekine, MD, Tokiko Nagamura-Inoue, MD,PhD, Seiichiro Kobayashi, MD,PhD

Blood (2006) 108 (11): 1845.

https://doi.org/10.1182/blood.V108.11.1845.1845

Published: 2006

Journal Articles

Hematopoietic Cell Differentiation from Common Marmoset (Callithrix jacchus) Embryonic Stem Cells by Their Genetic Manipulation Using the Third Generation Lentiviral Vector.

Ryo Kurita, Ph.D, Erika Sasaki, Ph.D, Takashi Hiroyama, Ph.D, Tomoko Yokoo, Yukoh Nakazaki, Ph.D, Kiyoko Izawa, Ph.D, Hajime Ishii, Yoshikuni Tanioka, Kisaburo Hanazawa, MD, Takao Hashiguchi, Yuan-Son Bai, Ph.D, MD, Yasushi Soda, Ph.D, MD, Sumiko Watanabe, Ph.D, Shigetaka Asano, MD, Kenzaburo Tani, Ph.D, MD

Blood (2004) 104 (11): 495.

https://doi.org/10.1182/blood.V104.11.495.495

Published: 2004

Journal Articles

Leptomycin B Overcomes Imatinib Resistance Mediated by Stromal Cells and Mutant BCR-ABL in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Cells.

Arinobu Tojo, MD, PhD, Kiyoko Izawa, PhD, Rieko Sekine, Tokiko Nagamura, MD, PhD, Minoru Yoshida, PhD, Takashi Tsuji, PhD

Blood (2004) 104 (11): 2089.

https://doi.org/10.1182/blood.V104.11.2089.2089

Published: 2004

Journal Articles

CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome–positive acute lymphoblastic leukemia cells

Blood (2004) 104 (5): 1442–1449.

https://doi.org/10.1182/blood-2004-02-0588

Published: 2004

Journal Articles

A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome–positive acute lymphoblastic leukemia

Yasushi Soda, Kenzaburo Tani, Yuansong Bai, Minoru Saiki, Minghan Chen, Kiyoko Izawa, Seiichiro Kobayashi, Satoshi Takahashi, Kaoru Uchimaru, Tomoko Kuwabara, Masaaki Warashina, Tsuyoshi Tanabe, Hiroyuki Miyoshi, Kanji Sugita, Shinpei Nakazawa, Arinobu Tojo, Kazunari Taira, Shigetaka Asano

Blood (2004) 104 (2): 356–363.

https://doi.org/10.1182/blood-2003-06-1948

Published: 2004

NARROW

A Mouse Homolog of Mutant Wasp Responsible for X-Linked Neutropenia Causes Reduced Myeloid Progenitor Activity but Rather Increased Neutrophil Compartment in Bone Marrow

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

In vivo leukemogenic potential of an interleukin 7 receptor α chain mutant in hematopoietic stem and progenitor cells

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

Unique Role of mTOR Inhibitor, Everolimus in Inducible Regulatory T Cells

The Significance of mTOR Inhibitor, Everolimus in TGF-β-Induced Regulatory T cells from Cord Blood

The in Vitro and In Vivo Oncogenic Activity of Homodimeric Mutant of Interleukin-7 Receptor a Chain (IL7Rα) Highlights the Significance of the IL7Rα/Jak1 Pathway in T-Cell Acute Lymphoblastic Leukemia

Bcr-Abl Impairs T Cell Development From Murine Induced Pluripotent Stem Cells and Hematopoietic Stem Cells; A Partial Explanation for the Concept That Ph+ Clone Never Involves T Cell Lineage in CML,

Hormone-Conditional Activation of Bcr-Abl Kinase Highlights Stat5 Anti-Apoptotic Pathway Prior to Promoting Cell Growth.

Leukemogenic Fusion Gene (p190 BCR-ABL) Transduction Into Hematopoietic Stem/Progenitor Cells In the Common Marmoset

Conditional Activation of Bcr-Abl Kinase Delineates Time-Dependent Transforming Events in Hematopoietic Cells.

Large Scale Selective Ex Vivo Expansion of CD4 + CD25 + FOXP3 + Regulatory T Cells from Peripheral Blood.

Development of a Unique In Vitro and In Vivo Model System of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph-ALL) with Emphasis on Cell to Cell Interaction.

Hematopoietic Cell Differentiation from Common Marmoset (Callithrix jacchus) Embryonic Stem Cells by Their Genetic Manipulation Using the Third Generation Lentiviral Vector.

Leptomycin B Overcomes Imatinib Resistance Mediated by Stromal Cells and Mutant BCR-ABL in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Cells.

CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome–positive acute lymphoblastic leukemia cells

A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome–positive acute lymphoblastic leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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