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Journal Articles

Characterization of the Severe Phenotype of Pyruvate Kinase Deficiency

Blood (2019) 134 (Supplement_1): 949.

https://doi.org/10.1182/blood-2019-125352

Published: 2019

Journal Articles

Prediction of Risk for Adverse Pregnancy Outcomes in Women with Sickle Cell Disease

A. Kinga Malinowski, MD MSc, FRCSC, Kevin H. M. Kuo, MDMSc,FRCPC, George A. Tomlinson, PhD BSc, MSc, Richard Ward, MSc, MRCP, FRCPath, Nadine Shehata, MDFRCPC,MSc

Blood (2019) 134 (Supplement_1): 1009.

https://doi.org/10.1182/blood-2019-130087

Published: 2019

Journal Articles

Rate of Sickle Hemoglobin Recovery in Sickle Cell Disease Patients Undergoing Red Blood Cell (RBC) Exchange Transfusion Is Associated with Age of Patients and Number of RBC Units Transfused

John Chinawaeze Aneke, MBBS, Aliraza Rajabali, Nafanta Fadiga, Stéphanie Forté, MD MSc, FRCPC, George A. Tomlinson, PhD BSc, MSc, Christine M. Cserti-Gazdewich, BSc, MD FRCPC, Christopher J. Patriquin, MDFRCPC,MSc, Richard Ward, MSc, MRCP, FRCPath, Jacob Pendergrast, MDFRCPC, David Barth, MD FRCPC, Kevin H. M. Kuo, MDMSc,FRCPC

Blood (2019) 134 (Supplement_1): 2170.

https://doi.org/10.1182/blood-2019-122072

Published: 2019

Journal Articles

Comorbidities and Complications in Adults with Pyruvate Kinase Deficiency

Blood (2019) 134 (Supplement_1): 2175.

https://doi.org/10.1182/blood-2019-123069

Published: 2019

Journal Articles

Pyruvate Kinase (PK) Protein and Enzyme Levels in the Diagnosis and Clinical Phenotype of PK Deficiency

Kathryn Addonizio, BA, Hanny Al-Samkari, MD, Bertil Glader, MD PhD, D Holmes Morton, MD, Satheesh Chonat, MD, Alexis A. Thompson, MD MPH, Kevin H. M. Kuo, MDMSc,FRCPC, Yaddanapudi Ravindranath, MBBS, Heng Wang, MD PhD, Jennifer A. Rothman, MD, Janet L. Kwiatkowski, MD MSCE, Charles Kung, PhD, Penelope A. Kosinski, MS, Hasan Al-Sayegh, MS, Wendy B. London, PhD, Rachael F. Grace, MD

Blood (2019) 134 (Supplement_1): 3515.

https://doi.org/10.1182/blood-2019-125248

Published: 2019

Journal Articles

Long-Term Safety and Efficacy of Mitapivat (AG-348), a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency: The DRIVE PK Study

Rachael F. Grace, MD, D. Mark Layton, MB BS, FRCP, FRCPCH, Frédéric Galactéros, MD PhD, Wilma Barcellini, MD, Eduard J. van Beers, MD PhD, Hassan M. Yaish, MD, Yaddanapudi Ravindranath, MBBS, Kevin H. M. Kuo, MDMSc,FRCPC, Sujit Sheth, MD, Janet L. Kwiatkowski, MD MSCE, Lei Hua, PhD, Peter F. Hawkins, PhD, Chris Mix, MD, Bertil Glader, MD PhD

Blood (2019) 134 (Supplement_1): 3512.

https://doi.org/10.1182/blood-2019-123406

Published: 2019

Journal Articles

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2019) 134 (Supplement_1): 3545.

https://doi.org/10.1182/blood-2019-122685

Published: 2019

Journal Articles

An Ongoing Global, Longitudinal, Observational Study of Patients with Pyruvate Kinase Deficiency: The PEAK Registry

Rachael F. Grace, MD, Paola Bianchi, BSc, PhD, Bertil Glader, MD PhD, Andreas Glenthøj, MD PhD, Bryan Jones, PhD, Hitoshi Kanno, MD PhD, Kevin H. M. Kuo, MDMSc,FRCPC, D. Mark Layton, MB ChB, Eduard J. van Beers, MD PhD, Joan-Lluis Vives Corrons, MD PhD, Tu Xu, MS, PhD

Blood (2019) 134 (Supplement_1): 2223.

https://doi.org/10.1182/blood-2019-123059

Published: 2019

Journal Articles

Predictors of the Rowland Universal Dementia Assessment Scale (RUDAS) Performance in Adults with Sickle Cell Disease

Stéphanie Forté, MD MSc, FRCPC, Florence Blais, Mathias Castonguay, Nafanta Fadiga, Richard Ward, MSc, MRCP, FRCPath, Béland Sébastien, PhD, Melanie Cohn, PhD CPsych, Denis Soulières, MD, Kevin H. M. Kuo, MDMSc,FRCPC

Blood (2019) 134 (Supplement_1): 2294.

https://doi.org/10.1182/blood-2019-129342

Published: 2019

Journal Articles

Patient Education Interventions for Improving Self-Management in Adults with Hemoglobinopathies: A Systematic Review and Meta-Analysis

Maha Munawar, BSc, Richard Ward, MSc, MRCP, FRCPath, Kate Uchendu, BScN, MN, NP-Adult, Rouhi Fazelzad, BSc, MISt, Janet Papadakos, Kevin H. M. Kuo, MDMSc,FRCPC

Blood (2019) 134 (Supplement_1): 5783.

https://doi.org/10.1182/blood-2019-131718

Published: 2019

Journal Articles

Mitapivat (AG-348), an Oral PK-R Activator, in Adults with Non-Transfusion Dependent Thalassemia: A Phase 2, Open-Label, Multicenter Study in Progress

Kevin H. M. Kuo, MDMSc,FRCPC, D. Mark Layton, MB BS, Katrin Uhlig, MD MS, Megan Lynch, MSN, NP, Li Liu, PhD, Elliott P. Vichinsky, MD

Blood (2019) 134 (Supplement_1): 2249.

https://doi.org/10.1182/blood-2019-123113

Published: 2019

Journal Articles

Allogeneic Hematopoietic Stem Cell Transplant Versus Gene Therapy in Sickle Cell Disease: A Systematic Review

Lianne E Rotin, MD PhD, Auro Viswabandya, MD, Rajat Kumar, MD, Kevin H. M. Kuo, MDMSc,FRCPC

Blood (2019) 134 (Supplement_1): 4714.

https://doi.org/10.1182/blood-2019-124989

Published: 2019

Journal Articles

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2018) 132 (Supplement 1): 163.

https://doi.org/10.1182/blood-2018-163

Published: 2018

Journal Articles

Is There a Role for Thromboprophylaxis in Sickle Cell Patients with Central Venous Access Devices?

Stéphanie Forté, MD MSc, FRCPC, Nafanta Fadiga, Olivia Pestrin, John Chinawaeze Aneke, MBBS, FMCPath, Shivani Bhat, MPH, Richard Ward, MBBS, MRCP, Kevin H. M. Kuo, MD MSc, FRCPC

Blood (2018) 132 (Supplement 1): 3518.

https://doi.org/10.1182/blood-2018-99-119716

Published: 2018

Journal Articles

Successful Management of Pregnancy with Severe Von Willebrand Disease in a Jehovah's Witness with Recombinant Von Willebrand Factor

Sajida Kazi, MRCP, FRCPATH, Ann Kinga Malinowski, MD MSc, FRCSC, Clare Whitehead, Kevin H. M. Kuo, MDMSc, FRCPC, Lynda Harrington, Nancy Watts, Chen Wang, MD PhD FRCPC, Nadine Shehata, MD FRCPC, MSc

Blood (2018) 132 (Supplement 1): 5077.

https://doi.org/10.1182/blood-2018-99-114949

Published: 2018

Journal Articles

Validation of Sickle Cell Disease Severity Score in a Cohort of Hemoglobin SC Disease Patients

Rebecca Marie Rosart, MD, Olivia A. Pestrin, George A. Tomlinson, PhD BSc, MSc, Richard Ward, MBBS, MRCP, Jacob Pendergrast, MD FRCPC, Andrew Binding, MD MSc, FRCPC, Kevin H. M. Kuo, MD MSc, FRCPC

Blood (2018) 132 (Supplement 1): 2287.

https://doi.org/10.1182/blood-2018-99-111364

Published: 2018

Journal Articles

Health Related Quality of Life and Fatigue in Patients with Pyruvate Kinase Deficiency

Blood (2018) 132 (Supplement 1): 4807.

https://doi.org/10.1182/blood-2018-99-113206

Published: 2018

Journal Articles

Real World Experience with Sublingual Fentanyl for the Treatment of Sickle Cell Vaso-Occlusive Episodes in Adults in a Tertiary Canadian Emergency Department

Hayley Merkeley, MD, Sam Sabbah, MBBS, MSc, Richard Ward, MBBS, MRCP, Kevin H. M. Kuo, MD MSc,FRCPC

Blood (2018) 132 (Supplement 1): 5879.

https://doi.org/10.1182/blood-2018-99-116676

Published: 2018

Journal Articles

Excellence in PNH in Canada (EPIC): A Single Centre Pilot Project Evaluating Disease Trajectory for PNH Patients Receiving Eculizumab

Michael James Vernon, MD BSc, Kevin H. M. Kuo, MD MSc, FRCPC, Rebecca Leroux, BSc, Christopher J. Patriquin, MD MSc, FRCPC

Blood (2018) 132 (Supplement 1): 4879.

https://doi.org/10.1182/blood-2018-99-112337

Published: 2018

Journal Articles

Should Women with Sickle Cell Disease be Administered Prophylactic Transfusions to Avoid Complications during Pregnancy?

Patricia Palcu, BSc, Kevin H. M. Kuo, MDMSc, FRCPC, Richard Ward, MBBS, MRCP, Nusrat Zaffar, MD, Ann Kinga Malinowski, MD MSc, FRCSC, Nadine Shehata, MD FRCPC, MSc

Blood (2018) 132 (Supplement 1): 3679.

https://doi.org/10.1182/blood-2018-99-112133

Published: 2018

NARROW

Characterization of the Severe Phenotype of Pyruvate Kinase Deficiency

Prediction of Risk for Adverse Pregnancy Outcomes in Women with Sickle Cell Disease

Rate of Sickle Hemoglobin Recovery in Sickle Cell Disease Patients Undergoing Red Blood Cell (RBC) Exchange Transfusion Is Associated with Age of Patients and Number of RBC Units Transfused

Comorbidities and Complications in Adults with Pyruvate Kinase Deficiency

Pyruvate Kinase (PK) Protein and Enzyme Levels in the Diagnosis and Clinical Phenotype of PK Deficiency

Long-Term Safety and Efficacy of Mitapivat (AG-348), a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency: The DRIVE PK Study

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

An Ongoing Global, Longitudinal, Observational Study of Patients with Pyruvate Kinase Deficiency: The PEAK Registry

Predictors of the Rowland Universal Dementia Assessment Scale (RUDAS) Performance in Adults with Sickle Cell Disease

Patient Education Interventions for Improving Self-Management in Adults with Hemoglobinopathies: A Systematic Review and Meta-Analysis

Mitapivat (AG-348), an Oral PK-R Activator, in Adults with Non-Transfusion Dependent Thalassemia: A Phase 2, Open-Label, Multicenter Study in Progress

Allogeneic Hematopoietic Stem Cell Transplant Versus Gene Therapy in Sickle Cell Disease: A Systematic Review

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Is There a Role for Thromboprophylaxis in Sickle Cell Patients with Central Venous Access Devices?

Successful Management of Pregnancy with Severe Von Willebrand Disease in a Jehovah's Witness with Recombinant Von Willebrand Factor

Validation of Sickle Cell Disease Severity Score in a Cohort of Hemoglobin SC Disease Patients

Health Related Quality of Life and Fatigue in Patients with Pyruvate Kinase Deficiency

Real World Experience with Sublingual Fentanyl for the Treatment of Sickle Cell Vaso-Occlusive Episodes in Adults in a Tertiary Canadian Emergency Department

Excellence in PNH in Canada (EPIC): A Single Centre Pilot Project Evaluating Disease Trajectory for PNH Patients Receiving Eculizumab

Should Women with Sickle Cell Disease be Administered Prophylactic Transfusions to Avoid Complications during Pregnancy?

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American Society of Hematology

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ASH Publications

American Society of Hematology

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