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Kevin G. Haworth
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Journal Articles

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes

Stosh Ozog, Nina D. Timberlake, Kip Hermann, Olivia Garijo, Kevin G. Haworth, Guoli Shi, Christopher M. Glinkerman, Lauren E. Schefter, Saritha D’Souza, Elizabeth Simpson, Gabriella Sghia-Hughes, Raymond R. Carillo, Dale L. Boger, Hans-Peter Kiem, Igor Slukvin, Byoung Y. Ryu, Brian P. Sorrentino, Jennifer E. Adair, Scott A. Snyder, Alex A. Compton, Bruce E. Torbett
Journal: Blood
Blood (2019) 134 (16): 1298–1311.
https://doi.org/10.1182/blood.2019000040
Published: 2019
Includes: Supplemental data
Journal Articles

Non-Genotoxic Conditioning Efficiently Depletes Host Hematopoietic Stem Cells and Facilitates Robust Multi-Lineage Engraftment in a Mouse Model of Fanconi Anemia

Meera Srikanthan, MD, Kevin G. Haworth, PhD, Christina M. Ironside, BS, Jerry Chen, Adam J. Hartigan, PhD, Rahul Palchaudhuri, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Hans-Peter Kiem, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2041.
https://doi.org/10.1182/blood-2018-99-116851
Published: 2018
Journal Articles

Engineering Resistance to CD33-Targeted Immunotherapy in Normal Hematopoiesis By CRISPR/Cas9-Deletion of CD33 Exon 2

Roland B. Walter, MD PhD MS, Olivier Humbert, PhD, George S. Laszlo, PhD, Sophie R. Sichel, BS, Christina M. Ironside, BS, Kevin G. Haworth, PhD, Olivia M. Bates, BA, Mary E. Beddoe, BS, Ray R. Carillo, BS, Hans-Peter Kiem, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2200.
https://doi.org/10.1182/blood-2018-99-117856
Published: 2018
Journal Articles

Novel Lineage Depletion and Manufacturing Allows for Unprecedented Preservation of Autologous Blood Stem Cells for Gene Therapy of Fanconi Anemia Complementation Group Α

Jennifer Adair, PhD, Devikha Chandrasekaran, MS, Stefanie Schmuck, BS, Gabriella Sghia-Hughes, BS, Grace Choi, BS, Anne Lee, BS, Kevin G Haworth, BS, PhD, Ann Woolfrey, MD, Lauri S Burroughs, MD, Pamela S. Becker, MD PhD, Hans-Peter Kiem, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2451.
https://doi.org/10.1182/blood.V130.Suppl_1.2451.2451
Published: 2017
Journal Articles

In Vivo HSC Transduction and Selection Results in Long-Term, High-Level Expression of Human Gamma Globin in Peripheral Blood Erythrocytes of Mice

Andre Lieber, MD PhD, Hongjie Wang, PhD, Nikoleta Psatha, PhD, Chang Li, PhD, Kevin G Haworth, BS, PhD, Anja Ehrhardt, PhD, Zsuzsanna Izsvak, Hans-Peter Kiem, MD PhD, George Stamatoyannopoulos, MD, Thalia Papayannopoulou, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4616.
https://doi.org/10.1182/blood.V130.Suppl_1.4616.4616
Published: 2017
Journal Articles

Dual-Method Clone Tracking in Nonhuman Primates Confirms Long-Term Hematopoietic Reconstitution Initiated By Early Engrafting Clones

Jennifer E Adair, PhD, Zachary K. Norgaard, MSc, Kevin G Haworth, PhD, Lauren E Schefter, BA, Kenric Tam, MD, Matthew Porteus, MD PhD, Hans-Peter Kiem, MD FACP
Journal: Blood
Blood (2016) 128 (22): 1475.
https://doi.org/10.1182/blood.V128.22.1475.1475
Published: 2016
Journal Articles

Comprehensive Integration Site Analysis of Human Immunodeficiency Virus during In Vivo Infections Reveals Genomic Regions of Enrichment and Clonal Expansion

Kevin G Haworth, PhD, Lauren E Schefter, BA, Zachary K. Norgaard, MSc, Jennifer E Adair, PhD, Hans-Peter Kiem, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2518.
https://doi.org/10.1182/blood.V128.22.2518.2518
Published: 2016
Journal Articles

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors

Maximilian Richter, Kamola Saydaminova, Roma Yumul, Rohini Krishnan, Jing Liu, Eniko-Eva Nagy, Manvendra Singh, Zsuzsanna Izsvák, Roberto Cattaneo, Wolfgang Uckert, Donna Palmer, Philip Ng, Kevin G. Haworth, Hans-Peter Kiem, Anja Ehrhardt, Thalia Papayannopoulou, André Lieber
Journal: Blood
Blood (2016) 128 (18): 2206–2217.
https://doi.org/10.1182/blood-2016-04-711580
Published: 2016
Includes: Supplemental data
Journal Articles

A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy

Jennifer E Adair, PhD, Kevin G Haworth, PhD, Guy Sauvageau, MD, PhD, Shelly Heimfeld, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2015) 126 (23): 4416.
https://doi.org/10.1182/blood.V126.23.4416.4416
Published: 2015
Journal Articles

CD133 + CD34 + HSPCs Are Not Significantly Increased in Fetal Liver Compared to Adult or Umbilical Cord HSPCs

Stefan Radtke, PhD, Kevin G Haworth, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2015) 126 (23): 2369.
https://doi.org/10.1182/blood.V126.23.2369.2369
Published: 2015
Journal Articles

In Vivo Selection Unmasks a Dormant Pool of Repopulating Hematopoietic Clones

Jennifer E Adair, PhD, Lauren E Schefter, B.A., Daniel R Humphrys, B.S., Kevin G Haworth, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2015) 126 (23): 242.
https://doi.org/10.1182/blood.V126.23.242.242
Published: 2015