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Justine E. Roderick
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Journal Articles

Dormancy Is a Feature of Therapy Resistant Mouse and Human Leukemia-Initiating Cells in T-ALL

Kevin O'Connor, Kensei Kishimoto, Irena Kuzma, Kelsey Wagner, Jonathan Selway, Kayleigh M Gallagher, Justine E. Roderick, David J. Curtis, Cedric Tremblay, Michelle A Kelliher
Journal: Blood
Blood (2022) 140 (Supplement 1): 8766–8767.
https://doi.org/10.1182/blood-2022-170475
Published: 2022
Journal Articles

Prostaglandin E 2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death

Justine E. Roderick, Kayleigh M. Gallagher, Leonard C. Murphy, Kevin W. O’Connor, Katherine Tang, Boyao Zhang, Michael A. Brehm, Dale L. Greiner, Jun Yu, Lihua Julie Zhu, Michael R. Green, Michelle A. Kelliher
Journal: Blood
Blood (2021) 137 (4): 500–512.
https://doi.org/10.1182/blood.2020005712
Published: 2021
Includes: Supplemental data
Journal Articles

Repression of the Orphan Nuclear Receptor Esrrb Results in Glucocorticoid Resistance in ALL

Kayleigh Gallagher, BS, Justine E. Roderick, PhD, Jun Yu, Julie Zhu, Michael R Green, PhD, Michelle Kelliher, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1259.
https://doi.org/10.1182/blood.V130.Suppl_1.1259.1259
Published: 2017
Journal Articles

A Hematopoietic RIPK1 Deficiency Triggers IFNγ-Mediated Necroptosis and Bone Marrow Failure

Sung Eun Lim, PhD, Joanne O'Donnell, PhD, Justine E. Roderick, PhD, Manolis Pasparakis, PhD, Michelle Kelliher, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3772.
https://doi.org/10.1182/blood.V130.Suppl_1.3772.3772
Published: 2017
Journal Articles

The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia

Gayle P. Pouliot, MD PhD, Melissa A. Burns, MD, James Degar, Chau Vo, Lisa Moreau, Justine E. Roderick, PhD, Bose Kochupurakkal, PhD, Sofie Peirs, PhD, Bjorn Menten, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Lewis B. Silverman, MD, Stephen E. Sallan, MD, Marian H. Harris, MD PhD, Kristen E. Stevenson, MS, Donna S. Neuberg, ScD, David M. Weinstock, MD, Andrew P. Weng, MD PhD, Michelle Kelliher, PhD, Pieter Van Vlierberghe, PhD, Alan D. D'Andrea, MD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2722.
https://doi.org/10.1182/blood.V130.Suppl_1.2722.2722
Published: 2017
Journal Articles

RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia

AHyun Choi, Anuradha Illendula, John A. Pulikkan, Justine E. Roderick, Jessica Tesell, Jun Yu, Nicole Hermance, Lihua Julie Zhu, Lucio H. Castilla, John H. Bushweller, Michelle A. Kelliher
Journal: Blood
Blood (2017) 130 (15): 1722–1733.
https://doi.org/10.1182/blood-2017-03-775536
Published: 2017
Includes: Supplemental data
Journal Articles

Identifying Mechanisms of Glucocorticoid Resistance in Relapsed Pediatric T-ALL

Justine E. Roderick, PhD, Kayleigh M Gallagher, BS, Katherine M Tang, BS, Olivia Kugler-Umana, BS, Lihua J Zhu, PhD, Michael R Green, MD PhD, Michelle Kelliher, PhD
Journal: Blood
Blood (2016) 128 (22): 2769.
https://doi.org/10.1182/blood.V128.22.2769.2769
Published: 2016
Journal Articles

IFNγ-Induced Necroptosis Contributes to Hematopoietic Stem and Progenitor Cell Death and Bone Marrow Failure

Joanne O'Donnell, PhD, Justine E. Roderick, PhD, Manolis Pasparakis, PhD, Michelle Kelliher, PhD
Journal: Blood
Blood (2016) 128 (22): 1485.
https://doi.org/10.1182/blood.V128.22.1485.1485
Published: 2016
Journal Articles

JAK/STAT Pathway Inhibition Reverts IL7-Induced Glucocorticoid Resistance in a Subset of Human T-Cell Acute Lymphoblastic Leukemia

Cristina Delgado-Martin, PhD, Kristin Shimano, MD, Matthew S Zinter, MD, Justin T. Wahlstrom, MD, Geoffrey A. Smith, Jack Taunton, PhD, Stuart S. Winter, MD, Justine E. Roderick, PhD, Michelle Kelliher, PhD, Terzah M. Horton, MD PhD, Brent L. Wood, MD PhD, David T Teachey, MD, Michelle L. Hermiston, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3963.
https://doi.org/10.1182/blood.V128.22.3963.3963
Published: 2016
Journal Articles

Ripk-Mediated Necroptosis Induces Inflammation and Bone Marrow Failure in Mice

Justine E. Roderick, PhD, Nicole Hermance, BS, Matija Zelic, BS, Matthew Simmons, PhD, Apostolos Polykratis, PhD, Manolis Pasparakis, PhD, Michelle Kelliher, PhD
Journal: Blood
Blood (2014) 124 (21): 1599.
https://doi.org/10.1182/blood.V124.21.1599.1599
Published: 2014
Journal Articles

c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells

Justine E. Roderick, Jessica Tesell, Leonard D. Shultz, Michael A. Brehm, Dale L. Greiner, Marian H. Harris, Lewis B. Silverman, Stephen E. Sallan, Alejandro Gutierrez, A. Thomas Look, Jun Qi, James E. Bradner, Michelle A. Kelliher
Journal: Blood
Blood (2014) 123 (7): 1040–1050.
https://doi.org/10.1182/blood-2013-08-522698
Published: 2014
Includes: Supplemental data
Journal Articles

C-Myc Inhibition Targets the Leukemia-Initiating Cells in a Tal1/Lmo2 mouse Model of T-ALL

Jessica Tesell, Michelle Kelliher, PhD, Nicole Hermance, Justine E. Roderick, PhD, James E Bradner, MD
Journal: Blood
Blood (2012) 120 (21): 1880.
https://doi.org/10.1182/blood.V120.21.1880.1880
Published: 2012