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Journal Articles

Impact of Traditional and E-Cigarette Smoking Metabolites on Acute Myeloid Leukemia

Shaikha Alqahtani, Huaxian Ma, Mary Figueroa, Alaina Poche, Deokhwa Nam, Joya Chandra
Journal: Blood
Blood (2024) 144 (Supplement 1): 5749.
https://doi.org/10.1182/blood-2024-211965
Published: 2024
Journal Articles

Investigating the Impact of Smoking Traditional and E-Cigarettes on Acute Myeloid Leukemia Progression

Shaikha Alqahtani, Mary Figueroa, Huaxian Ma, Joya Chandra
Journal: Blood
Blood (2023) 142 (Supplement 1): 5702.
https://doi.org/10.1182/blood-2023-185349
Published: 2023
Journal Articles

Cigarette Smoke or Cigarette Condensate Exposure Accelerates Growth of FLT3-ITD AML Models, Induces Oxidative Stress, and Alters DNA Methylation

Mary Figueroa, Megan R Rodriguez, Marcos Estecio, Yue Lu, Seyed Javad Moghaddam, Elias J. Jabbour, Marina Konopleva, Courtney D. DiNardo, Joya Chandra
Journal: Blood
Blood (2021) 138 (Supplement 1): 3331.
https://doi.org/10.1182/blood-2021-145944
Published: 2021
Journal Articles

Cigarette Smoke or Cigarette Condensate Exposure Enhances Growth of FLT3-ITD AML Models and Alters DNA Methylation and Leukemic Gene Expression

Mary Figueroa, BS, Maninder Khosla, BS, Yue Lu, PhD, Marcos Estecio, PhD, Seyed Javad Moghaddam, MD, Elias Jabbour, MD, Marina Konopleva, MD PhD, Courtney D. DiNardo, MD MSCE, Joya Chandra, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-142478
Published: 2020
Journal Articles

The Impact of Smoking on Survival in Patients (Pts) with Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor (TKI)

Koji Sasaki, MD, Josep-Maria Ribera, MD PhD, Mary Figueroa, BS, Farhad Ravandi, MD, Nicholas J. Short, MD, Guillermo Garcia-Manero, MD, Naval G. Daver, MD, Tapan M. Kadia, MD, Marina Y Konopleva, MD PhD, Nitin Jain, MD, Ghayas C. Issa, MD, Zeev E. Estrov, MD, Rebecca Garris, MSc, Rita Khouri, Patrice Nasnas, MD, Courtney D. DiNardo, MDMSc, Kiran Naqvi, MDMPH, Steven M. Kornblau, MD, Guillermo Montalban-Bravo, MD, Naveen Pemmaraju, MD, Jorge E. Cortes, MD, Susan M. O'Brien, MD, Joya Chandra, PhD, Hagop M. Kantarjian, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3815.
https://doi.org/10.1182/blood-2019-129396
Published: 2019
Journal Articles

Acceleration of AML Progression By Cigarette Smoke Exposure or Condensate Exposure and Associated DNA Methylation Alterations

Mary Figueroa, BS, Mansour Alfayez, MD, Yue Lu, PhD, Marcos Estecio, PhD, Seyed Javad Moghaddam, MD, Marina Y Konopleva, MD PhD, Elias Jabbour, MD, Courtney D. DiNardo, MDMSc, Joya Chandra, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2554.
https://doi.org/10.1182/blood-2019-127216
Published: 2019
Journal Articles

Trimethylated H3K27, and Di- and Trimethylated H3K4 Proteomic Profiling Distinguishes Acute Lymphoid Leukemia (ALL) from Acute Myeloid Leukemia (AML) and Associates with Overall Survival and Tyrosine Kinase Inhibitor Sensitivity in Adult ALL

Anneke D. van Dijk, BS, Fieke W Hoff, BSc, Yihua Qiu, Mary Figueroa, BS, Joya Chandra, PhD, Elias Jabbour, MD, Eveline S. de Bont, MD PhD, Steven M. Kornblau, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1460.
https://doi.org/10.1182/blood-2019-124960
Published: 2019
Journal Articles

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

Marisa J Hornbaker, B.S., Mary E Irwin, PhD, LaNisha Patterson, B.S., Shelley M Herbrich, MS, Patrick Zweidler-McKay, MD PhD, Joya Chandra, PhD
Journal: Blood
Blood (2015) 126 (23): 2470.
https://doi.org/10.1182/blood.V126.23.2470.2470
Published: 2015
Journal Articles

Accelerated Degradation of cFLIP Mediated By Inhibition of Methyltransferases Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Frank K Braun, PhD, Rohit Mathur, PhD, Lalit Sehgal, PhD, Rachel Wilkie-Grantham, Joya Chandra, PhD, Zuzana Berkova, PhD, Felipe Samaniego, MD
Journal: Blood
Blood (2014) 124 (21): 920.
https://doi.org/10.1182/blood.V124.21.920.920
Published: 2014
Journal Articles

Unique Apoptotic Effects Of Panobinostat and Marizomib In Acute Myeloid Leukemia and Bortezomib-Resistant Models

Fernando F. Corrales-Medina, M.D., Daniela E. Egas Bejar, M.D., Christa Manton, B.S., Blake Johnson, M.S., Mary E Irwin, Ph.D., Robert Z. Orlowski, M.D., Ph.D., Joya Chandra, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 3837.
https://doi.org/10.1182/blood.V122.21.3837.3837
Published: 2013
Journal Articles

Uncovering Cardioprotective Strategies For Anthracycline Therapy By Analysis Of Redox and Apoptotic Effects

Daniela E. Egas Bejar, M.D., Joy M. Fulbright, M.D., Fernando F. Corrales-Medina, M.D., Mary E. Irwin, Ph.D., Blake Johnson, M.S., Joya Chandra, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 1293.
https://doi.org/10.1182/blood.V122.21.1293.1293
Published: 2013
Journal Articles

HDAC and LSD1 Inhibitors Synergize to Induce Cell Death in Acute Leukemia Cells

Lorimar Ramirez, MD, Melissa Singh, PhD, Joya Chandra, PhD
Journal: Blood
Blood (2011) 118 (21): 1427.
https://doi.org/10.1182/blood.V118.21.1427.1427
Published: 2011
Journal Articles

A Pilot Study Investigating the Relationship Between Diet and Oxidative Stress in Infants Receiving Therapy for Acute Leukemia

Phillip D Knouse, M.S., Mayurika Pise, B.M.M.S., Jalissa N Furr, Rhea Li, BS, MPH, Donna A Bell, M.S.N., RN, FNP, Lisa L Triche, M.S.N., RN, CPNP, Shana L Palla, M.S., Joya Chandra, PhD
Journal: Blood
Blood (2011) 118 (21): 4228.
https://doi.org/10.1182/blood.V118.21.4228.4228
Published: 2011
Journal Articles

Small Molecule Inhibitors of HER2 Inhibit Proliferative Signaling and Promote Apoptosis in Ph+ ALL

Mary E Irwin, PhD, Laura Nelson, PhD, Janice M Santiago-O'Farrill, Claudia P Miller, PhD, Doris R. Siwak, PhD, Gordon B. Mills, MD, PhD, Shulin Li, PhD, Dennis P Hughes, MD, PhD, Joya Chandra, PhD
Journal: Blood
Blood (2011) 118 (21): 1397.
https://doi.org/10.1182/blood.V118.21.1397.1397
Published: 2011
Journal Articles

“Limiting Anthracycline-Induced Cardiotoxicity Using Amrubicin in Leukemia Systems”.

Joy Marie Fulbright, M.D., Joya Chandra, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 3760.
https://doi.org/10.1182/blood.V114.22.3760.3760
Published: 2009
Journal Articles

Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells

Claudia P. Miller, Sharmistha Rudra, Michael J. Keating, William G. Wierda, Michael Palladino, Joya Chandra
Journal: Blood
Blood (2009) 113 (18): 4289–4299.
https://doi.org/10.1182/blood-2008-08-174797
Published: 2009
Journal Articles

BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous leukemia

Brief Report
Kechen Ban, Yin Gao, Hesham M. Amin, Adrienne Howard, Claudia Miller, Quan Lin, Xiaohong Leng, Mark Munsell, Menashe Bar-Eli, Ralph B. Arlinghaus, Joya Chandra
Journal: Blood
Blood (2008) 111 (5): 2904–2908.
https://doi.org/10.1182/blood-2007-05-091769
Published: 2008
Journal Articles

Potentiation of Reactive Oxygen Species Is a Marker for Synergistic Cytotoxicity of MS-275 and 5-Azacytidine in Leukemic Cells.

Shan Gao, Claudia Miller, Jessica Boklan, Joya Chandra
Journal: Blood
Blood (2007) 110 (11): 4343.
https://doi.org/10.1182/blood.V110.11.4343.4343
Published: 2007
Journal Articles

Induction of Oxidative Stress and Glutathione Depletion by ABT-737, a Novel Small Molecule Inhibitor of Bcl-2, Contributes to Cytotoxicity in Leukemia Cells.

Joya Chandra, PhD, Adrienne Howard, Kathleen Jensen, Ray Meyn, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 4336.
https://doi.org/10.1182/blood.V110.11.4336.4336
Published: 2007
Journal Articles

NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells

Claudia P. Miller, Kechen Ban, Melanie E. Dujka, David J. McConkey, Mark Munsell, Michael Palladino, Joya Chandra
Journal: Blood
Blood (2007) 110 (1): 267–277.
https://doi.org/10.1182/blood-2006-03-013128
Published: 2007