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Journal Articles

JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML

Riikka Karjalainen, Tea Pemovska, Mihaela Popa, Minxia Liu, Komal K. Javarappa, Muntasir M. Majumder, Bhagwan Yadav, David Tamborero, Jing Tang, Dmitrii Bychkov, Mika Kontro, Alun Parsons, Minna Suvela, Mireia Mayoral Safont, Kimmo Porkka, Tero Aittokallio, Olli Kallioniemi, Emmet McCormack, Bjørn T. Gjertsen, Krister Wennerberg, Jonathan Knowles, Caroline A. Heckman
Journal: Blood
Blood (2017) 130 (6): 789–802.
https://doi.org/10.1182/blood-2016-02-699363
Published: 2017
Includes: Supplemental data
Journal Articles

JAK1/2 and BCL2 Inhibitors Synergize to Counter-Act Bone Marrow Stromal Cell-Induced Protection of AML

Riikka Karjalalainen, Tea Pemovska, Muntasir Mamun Majumder, Bhagwan Yadav, Jing Tang, Mika Kontro, Bjørn Gjertsen, MD PhD, Alun Parsons, Minna Suvela, Kimmo Porkka, Tero Aittokallio, Olli Kallioniemi, Krister Wennerberg, Jonathan Knowles, Caroline Heckman
Journal: Blood
Blood (2015) 126 (23): 867.
https://doi.org/10.1182/blood.V126.23.867.867
Published: 2015
Journal Articles

Identification Of AML Subtype-Selective Drugs By Functional Ex Vivo Drug Sensitivity and Resistance Testing and Genomic Profiling

Tea Pemovska, MSc, Mika Kontro, MD, Bhagwan Yadav, MSc, Henrik Edgren, PhD, Samuli Eldfors, MSc, Agnieszka Szwajda, MSc, Henrikki Almusa, MSc, Maxim Bespalov, PhD, Pekka Ellonen, MSc, Erkki Elonen, MD, PhD, Bjorn T Gjertsen, MD PhD, Riikka Karjalainen, MSc, Evgeny Kulesskiy, MSc, Sonja Lagström, MSc, Anna Lehto, MSc, Maija Lepistö, MSc, Tuija Lundan, PhD, Muntasir Mamun Majumder, MSc, Jesus Maria Lopez Marti, PhD, Pirkko Mattila, PhD, Astrid Murumägi, PhD, Satu Mustjoki, MD, PhD, Aino Palva, MSc, Alun Parsons, MSc, Tero Pirttinen, MD, Maria E Rämet, MD, Minna Suvela, BSc, Laura Turunen, MSc, Imre Västrik, PhD, Maija Wolf, PhD, Jonathan Knowles, PhD, Tero Aittokallio, PhD, Caroline A Heckman, PhD, Kimmo Porkka, MD, PhD, Olli Kallioniemi, MD, PhD, Krister Wennerberg, PhD
Journal: Blood
Blood (2013) 122 (21): 482.
https://doi.org/10.1182/blood.V122.21.482.482
Published: 2013
Journal Articles

Development of a Cancer Pharmacopeia-Wide Ex-Vivo Drug Sensitivity and Resistance Testing (DSRT) Platform: Identification of MEK and mTOR As Patient-Specific Molecular Drivers of Adult AML and Potent Therapeutic Combinations with Dasatinib

Mika Kontro, MD, Caroline Heckman, PhD, Evgeny Kulesskiy, MSc, Tea Pemovska, MSc, Maxim Bespalov, PhD, Samuli Eldfors, MSc, Elonen Erkki, MD, PhD, Riikka Karjalainen, MSc, Jonathan Knowles, PhD, Disha Malani, MSc, Muntasir Mamun Majumder, MSc, John Patrick Mpindi, MSc, PhD, Astrid Murumägi, PhD, Satu Mustjoki, MD, PhD, Laura Turunen, MSc, Maija Wolf, PhD, Kimmo Porkka, MD, PhD, Krister Wennerberg, PhD, Olli Kallioniemi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2487.
https://doi.org/10.1182/blood.V118.21.2487.2487
Published: 2011
Journal Articles

Recurrent Missense Mutations in the STAT3 Gene in LGL Leukemia Provide Insights to Pathogenetic Mechanisms and Suggest Potential Diagnostic and Therapeutic Applications

Hanna Koskela, MD, Samuli Eldfors, MSc, Henrikki Almusa, MSc, Emma Andersson, Pekka Ellonen, BSc, Henrik Edgren, MSc, Pirjo Koistinen, MD, PhD, Taru Kuittinen, MD, PhD, Kati Penttinen, Jonathan Knowles, PhD, Janna Saarela, MD, PhD, Olli Kallioniemi, MD, PhD, Krister Wennerberg, PhD, Kimmo Porkka, MD, PhD, Caroline Heckman, PhD, Satu Mustjoki, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 936.
https://doi.org/10.1182/blood.V118.21.936.936
Published: 2011