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Journal Articles

Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Riikka Karjalainen, Minxia Liu, Ashwini Kumar, MRes, Alun Parsons, Liye He, Dishaben Rameshbhai Malani, MSc, Mika Kontro, MD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2634.
https://doi.org/10.1182/blood-2018-99-118890
Published: 2018
Journal Articles

Elevated Expression of the S100A8/S100A9 Complex in AML Correlates with Reduced Sensitivity to the BCL2 Inhibitor Venetoclax

Riikka Karjalainen, Minxia Liu, Ashwini Kumar, MRes, Alun Parsons, Mika Kontro, MD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 298.
https://doi.org/10.1182/blood.V130.Suppl_1.298.298
Published: 2017
Journal Articles

JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML

Riikka Karjalainen, Tea Pemovska, Mihaela Popa, Minxia Liu, Komal K. Javarappa, Muntasir M. Majumder, Bhagwan Yadav, David Tamborero, Jing Tang, Dmitrii Bychkov, Mika Kontro, Alun Parsons, Minna Suvela, Mireia Mayoral Safont, Kimmo Porkka, Tero Aittokallio, Olli Kallioniemi, Emmet McCormack, Bjørn T. Gjertsen, Krister Wennerberg, Jonathan Knowles, Caroline A. Heckman
Journal: Blood
Blood (2017) 130 (6): 789–802.
https://doi.org/10.1182/blood-2016-02-699363
Published: 2017
Includes: Supplemental data
Journal Articles

Targeting of JAK/STAT Signaling to Reverse Stroma-Induced Cytoprotection Against BCL2 Antagonist Venetoclax in Acute Myeloid Leukemia

Riikka Karjalainen, Mihaela Popa, Dr, Minxia Liu, Mika Kontro, Mireia Mayoral Safont, Alun Parsons, MSc, Kimmo Porkka, MD PhD, Krister Wennerberg, Emmet McCormack, Dr, PhD, Bjørn T. Gjertsen, Caroline A Heckman, PhD
Journal: Blood
Blood (2016) 128 (22): 32.
https://doi.org/10.1182/blood.V128.22.32.32
Published: 2016