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Journal Articles

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation

Kellie R. Machlus, Stephen K. Wu, Deborah J. Stumpo, Thomas S. Soussou, David S. Paul, Robert A. Campbell, Hermann Kalwa, Thomas Michel, Wolfgang Bergmeier, Andrew S. Weyrich, Perry J. Blackshear, John H. Hartwig, Joseph E. Italiano, Jr

Blood (2016) 127 (11): 1468–1480.

https://doi.org/10.1182/blood-2015-08-663146

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets

Antonija Jurak Begonja, Fred G. Pluthero, Worawit Suphamungmee, Silvia Giannini, Hilary Christensen, Richard Leung, Richard W. Lo, Fumihiko Nakamura, William Lehman, Markus Plomann, Karin M. Hoffmeister, Walter H. A. Kahr, John H. Hartwig, Hervé Falet

Blood (2015) 126 (1): 80–88.

https://doi.org/10.1182/blood-2014-07-587600

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein

Markus Bender, Jonathan N. Thon, Allen J. Ehrlicher, Stephen Wu, Linas Mazutis, Emoke Deschmann, Martha Sola-Visner, Joseph E. Italiano, John H. Hartwig

Blood (2015) 125 (5): 860–868.

https://doi.org/10.1182/blood-2014-09-600858

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

The F-BAR Protein PACSIN2 Regulates Platelet Intracellular Membrane Architecture and in Vivo Hemostatic Functions

Terese Jönsson, Fred G Pluthero, Antonija Jurak Begonja, Jan Kormann, Mélanie Demers, Denisa D Wagner, Markus Plomann, John H Hartwig, Walter H Kahr, Hervé Falet

Blood (2014) 124 (21): 4154.

https://doi.org/10.1182/blood.V124.21.4154.4154

Published: 2014

Journal Articles

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

Simon Stritt, Markus Bender, Paquita Nurden, MD PhD, Judith van Eeuwijk, Barbara Zieger, Prof, Karim Kentouche, MD, Harald Schulze, Prof, Henner Morbach, MD, David Stegner, PhD, Katrin G Heinze, PhD, Sebastian Dütting, PhD, Shuchi Gupta, PhD, Walter Witke, Prof, Hervé Falet, PhD, Alain Fischer, Prof, John H. Hartwig, Prof, Bernhard Nieswandt, Prof

Blood (2014) 124 (21): 4200.

https://doi.org/10.1182/blood.V124.21.4200.4200

Published: 2014

Journal Articles

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Renata Grozovsky, PhD, Antonija Jurak Begonja, John H. Hartwig, Prof, Herve Falet, PhD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 2.

https://doi.org/10.1182/blood.V124.21.2.2

Published: 2014

Journal Articles

Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion

Yanfeng Wang, Liang Zhao, Aae Suzuki, Lurong Lian, Sang H. Min, Ziqian Wang, Rustem I. Litvinov, Timothy J. Stalker, Tadayuki Yago, Arkadiusz G. Klopocki, David W. Schmidtke, Helen Yin, John K. Choi, Rodger P. McEver, John W. Weisel, John H. Hartwig, Charles S. Abrams

Blood (2013) 121 (14): 2743–2752.

https://doi.org/10.1182/blood-2012-07-445205

Published: 2013

Includes: Supplemental data

Journal Articles

Clearance of Desialylated Platelets by the Hepatic Asialoglycoprotein Receptor Regulates TPO Homeostasis in Vivo .

Renata Grozovsky, PhD, Antonija Jurak Begonja, PhD, John H. Hartwig, PhD, Karin M. Hoffmeister, MD

Blood (2012) 120 (21): 2170.

https://doi.org/10.1182/blood.V120.21.2170.2170

Published: 2012

Journal Articles

The origin and function of platelet glycosyltransferases

Hans H. Wandall, Viktoria Rumjantseva, Anne Louise Tølbøll Sørensen, Sunita Patel-Hett, Emma C. Josefsson, Eric P. Bennett, Joseph E. Italiano, Jr, Henrik Clausen, John H. Hartwig, Karin M. Hoffmeister

Blood (2012) 120 (3): 626–635.

https://doi.org/10.1182/blood-2012-02-409235

Published: 2012

Includes: Supplemental data

Journal Articles

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

Grace M. Thomas, Carla Carbo, Brian R. Curtis, Kimberly Martinod, Irina B. Mazo, Daphne Schatzberg, Stephen M. Cifuni, Tobias A. Fuchs, Ulrich H. von Andrian, John H. Hartwig, Richard H. Aster, Denisa D. Wagner

Blood (2012) 119 (26): 6335–6343.

https://doi.org/10.1182/blood-2012-01-405183

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice

A. J. Gerard Jansen, Emma C. Josefsson, Viktoria Rumjantseva, Qiyong Peter Liu, Hervé Falet, Wolfgang Bergmeier, Stephen M. Cifuni, Robert Sackstein, Ulrich H. von Andrian, Denisa D. Wagner, John H. Hartwig, Karin M. Hoffmeister

Blood (2012) 119 (5): 1263–1273.

https://doi.org/10.1182/blood-2011-05-355628

Published: 2012

Includes: Supplemental data

Journal Articles

Extracellular DNA Traps Are Associated with Pathogenesis of TRALI in Humans and Mice

Grace M. Thomas, PhD, Carla Carbo, PhD, Brian Curtis, PhD, Kimberly Martinod, BA, BS, Irina B. Mazo, MD, PhD, Daphne Schatzberg, BS, Stephen M. Cifuni, BS, Tobias A. Fuchs, PhD, Ulrich H. von Andrian, MD, PhD, John H. Hartwig, PhD, Richard H. Aster, MD, Denisa D. Wagner, PhD

Blood (2011) 118 (21): 37.

https://doi.org/10.1182/blood.V118.21.37.37

Published: 2011

Journal Articles

The F-BAR Protein PACSIN 2 Specifically Coats the Anastomosing Intracellular Membrane Systems of Platelets and Megakaryocytes,

Terese Jónsson, MS, Antonija Jurak Begonja, PhD, Jan Kormann, MS, Barbara Merkl, MS, Fred Pluthero, PhD, Walter H. Kahr, MD, PhD, John H. Hartwig, PhD, Markus Plomann, PhD, Hervé Falet, PhD

Blood (2011) 118 (21): 3261.

https://doi.org/10.1182/blood.V118.21.3261.3261

Published: 2011

Journal Articles

Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets

Gerard Jansen, MD, PhD, MSC, Emma C Josefsson, PhD, Qiyong Peter Liu, PhD, Viktoria Rumjantseva, PhD, Herve Falet, PhD, Renata Grozovsky, PhD, Wolfgang Bergmeier, PhD, Denisa D. Wagner, PhD, John H. Hartwig, PhD, Karin M. Hoffmeister, MD

Blood (2011) 118 (21): 1133.

https://doi.org/10.1182/blood.V118.21.1133.1133

Published: 2011

Journal Articles

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

Antonija Jurak Begonja, PhD, Lilly Nguyen, Joseph E. Italiano, Jr., PhD, Herve Falet, PhD, Karina F. Meiri, PhD, John H. Hartwig, PhD

Blood (2011) 118 (21): 2201.

https://doi.org/10.1182/blood.V118.21.2201.2201

Published: 2011

Journal Articles

Size Limits the Ability of Platelets to Undergo Abcission

Jonathan Noah Thon, Ph.D., Hannah Macleod, Antonija Jurak Begonja, PhD, Jie Zhu, Ph.D., Kun-Chun Lee, Ph.D., Alex Mogilner, Ph.D., John H. Hartwig, PhD, Joseph E. Italiano, Jr., PhD

Blood (2011) 118 (21): 4821.

https://doi.org/10.1182/blood.V118.21.4821.4821

Published: 2011

Journal Articles

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

Antonija Jurak Begonja, Karin M. Hoffmeister, John H. Hartwig, Hervé Falet

Blood (2011) 118 (8): 2285–2295.

https://doi.org/10.1182/blood-2011-04-348482

Published: 2011

Journal Articles

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

Sunita Patel-Hett, Hongbei Wang, Antonija J. Begonja, Jonathan N. Thon, Eva C. Alden, Nancy J. Wandersee, Xiuli An, Narla Mohandas, John H. Hartwig, Joseph E. Italiano, Jr

Blood (2011) 118 (6): 1641–1652.

https://doi.org/10.1182/blood-2011-01-330688

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Filamin A Deficiency Leads to Premature Platelet Formation and Increased Clearance

Antonija Jurak Begonja, PhD, Sarah E. Weber, BS, Karin M. Hoffmeister, MD, John H. Hartwig, PhD, Herve Falet, PhD

Blood (2010) 116 (21): 2027.

https://doi.org/10.1182/blood.V116.21.2027.2027

Published: 2010

Journal Articles

ADF/n-cofilin–dependent actin turnover determines platelet formation and sizing

Markus Bender, Anita Eckly, John H. Hartwig, Margitta Elvers, Irina Pleines, Shuchi Gupta, Georg Krohne, Elisabeth Jeanclos, Antje Gohla, Christine Gurniak, Christian Gachet, Walter Witke, Bernhard Nieswandt

Blood (2010) 116 (10): 1767–1775.

https://doi.org/10.1182/blood-2010-03-274340

Published: 2010

Includes: Multimedia, Supplemental data

NARROW

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets

Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein

The F-BAR Protein PACSIN2 Regulates Platelet Intracellular Membrane Architecture and in Vivo Hemostatic Functions

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion

Clearance of Desialylated Platelets by the Hepatic Asialoglycoprotein Receptor Regulates TPO Homeostasis in Vivo .

The origin and function of platelet glycosyltransferases

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice

Extracellular DNA Traps Are Associated with Pathogenesis of TRALI in Humans and Mice

The F-BAR Protein PACSIN 2 Specifically Coats the Anastomosing Intracellular Membrane Systems of Platelets and Megakaryocytes,

Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

Size Limits the Ability of Platelets to Undergo Abcission

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

Filamin A Deficiency Leads to Premature Platelet Formation and Increased Clearance

ADF/n-cofilin–dependent actin turnover determines platelet formation and sizing

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American Society of Hematology

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ASH Publications

American Society of Hematology

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