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Journal Articles

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Blood (2019) 134 (Supplement_1): 1692.

https://doi.org/10.1182/blood-2019-128573

Published: 2019

Journal Articles

Germline Tissues and DNA Sequencing Analysis Methods for Optimal Somatic Variant Detection in Myelodysplastic Syndrome (MDS)

Eric Padron, MD, Jamie Teer, PhD, Markus Christian Ball, PhD, Jeffrey S Painter, BS, Rami S. Komrokji, MD, Ling Zhang, MD, Lynn C. Moscinski, MD, Mikkael A. Sekeres, MD MS, Steven D. Gore, MD, Rafael Bejar, MD PhD, Matthew J. Walter, MD, Pearlie Epling-Burnette, PhD PharmD

Blood (2017) 130 (Supplement 1): 1685.

https://doi.org/10.1182/blood.V130.Suppl_1.1685.1685

Published: 2017

Journal Articles

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

Eric Padron, MD, Jeffrey S Painter, BS, Adam W Mailloux, PhD, Kathy L. McGraw, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Geoffrey Yarranton, PhD, Jeffrey E Lancet, MD, Rami S. Komrokji, MD, Alan F. List, MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2012) 120 (21): 3793.

https://doi.org/10.1182/blood.V120.21.3793.3793

Published: 2012

Journal Articles

Increased Group B Killer Cell Immunoglobulin-Like Receptor (KIR) Haplotypes with Mismatched MHC Class I and Altered NK Repertoire Distribution in Bone Marrow Failure Syndromes

Jeffrey S Painter, BS, Jong Park, PhD, Michael J Clemente, Christine L. O'Keefe, PhD, Sheng Wei, MD, Jaroslaw P. Maciejewski, MD, PhD, Ron Paquette, MD, PhD, Thomas P. Loughran, Jr., M.D., Alan F. List, MD, Pearlie K Epling-Burnette, PhD

Blood (2011) 118 (21): 2412.

https://doi.org/10.1182/blood.V118.21.2412.2412

Published: 2011

Journal Articles

Autoproliferation Contributes to Clonal Expansion and Changes In Cellular Topography In T Cell Large Granular Lymphocyte (LGL) Leukemia

JianXiang Zou, MD, Jeffrey S Painter, BS, Fanqi Bai, MD, Lubomir Sokol, MD, PhD, Thomas P. Loughran, Jr., MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2010) 116 (21): 1373.

https://doi.org/10.1182/blood.V116.21.1373.1373

Published: 2010

Journal Articles

Phase 2 Multicenter Trial of Rabbit Anti-Thymocyte Serotherapy In Myelodysplastic Syndrome: Rate of Hematological Improvement Associated with Pre-Treatment Disease Duration

P.K. Epling-Burnette, PharmD, PhD, Rami S. Komrokji, MD, Jaroslaw P Maciejewski, MD, PhD, FACP, Mikkael A. Sekeres, MD, MS, Ronald Paquette, MD, Sheng Wei, MD, Jeffrey S Painter, BS, Fanqi Bai, MD, William J Fulp, Jennifer Paleveda-Pena, Dung-Tsa Chen, PhD, Alan F. List, MD

Blood (2010) 116 (21): 602.

https://doi.org/10.1182/blood.V116.21.602.602

Published: 2010

Journal Articles

Importance of T-Cell Proliferative Stress In Myelodysplastic Syndrome

Lili Yang, PhD, Amber Schmidt, Undergraduate, Rami Komrokji, MD, Jeffrey S. Painter, BS, Ashley Cole, Alan F. List, MD, Dana E. Rollison, PhD, P.K. Epling-Burnette, PharmD, PhD

Blood (2010) 116 (21): 2939.

https://doi.org/10.1182/blood.V116.21.2939.2939

Published: 2010

Journal Articles

Genetic Disparities in Killer Cell Immunoglobulin-Like Receptors (KIR) and MHC Class I in Bone Marrow Failure Syndromes

P.K. Epling-Burnette, PhD, Jeffrey S. Painter, BS, H.-S. Lee, PhD, Jong Park, Michael Clemente, MS, Christine O’Keefe, MD, Tie-Ying Wei, BS, Sheng Wei, MD, Jaroslaw Maciejewski, Thomas P. Loughran, Jr., MD, Ron Paquette, MD, Alan F. List, MD, Julie Y Djeu, PhD

Blood (2008) 112 (11): 4121.

https://doi.org/10.1182/blood.V112.11.4121.4121

Published: 2008

Journal Articles

Altered Naive and Memory T Cell Homeostasis and Immunosenescence Characterize Younger Patients with Immunosuppressive-Responsive Myelodysplastic Syndrome

JianXiang Zou, MD, Dana E Rollison, PhD, David Boulware, MS, Elaine M. Sloand, MD, Loretta Pfannes, BS, Fanqi Bai, MD, Jeffrey S. Painter, BS, Sheng Wei, MD, Denise Cosgrove, RN, Alan F. List, MD, P.K. Epling-Burnette, PhD

Blood (2008) 112 (11): 3647.

https://doi.org/10.1182/blood.V112.11.3647.3647

Published: 2008

Journal Articles

First Clinical Report of Tipifarnib for the Treatment of T-Large Granular Lymphocyte (LGL) Leukemia.

P.K. Epling-Burnette, PhD, Lubomir Sokol, MD, Lynn Moscinski, MD, Magda Elkabani, MD, Fanqi Bai, MD, Michelle Blaskovich, BS, JianXiang Zou, MD, Jeffrey S. Painter, BS, Said Sebti, PhD, Thomas P. Loughran, MD

Blood (2007) 110 (11): 3132.

https://doi.org/10.1182/blood.V110.11.3132.3132

Published: 2007

Journal Articles

Constitutive Activation of Ras and Mitogen-Activated Protein Kinase (MAPK/ERK) in LGL Leukemia Unrelated to Activating Mutations in N and KRas Genes.

Jeffrey S. Painter, BS, Angela Costellanos, Fanqi Bai, MD, Sheng Wei, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2007) 110 (11): 3180.

https://doi.org/10.1182/blood.V110.11.3180.3180

Published: 2007

Journal Articles

Th2 Polarization Induced by the Farnesyltransferase Inhibitor Tipifarnib (Zarnestra®, R115777) through Suppression of T-bet.

Fanqi Bai, MD, J.-X. Zou, MD, Sheng Wei, MD, Jeffrey S. Painter, BS, Michelle Blaskovich, Bs, Said Sebti, PhD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2007) 110 (11): 1331.

https://doi.org/10.1182/blood.V110.11.1331.1331

Published: 2007

Journal Articles

Aberrant NK Receptor Signaling Associated with Large Granular Lymphoycte Leukemia and Primary Pulmonary Hypertension.

P.K. Epling-Burnette, PhD, Xianhong Chen, Junmin Zhou, Fanqi Bai, MD, Sokol Lubomir, MD, Edna Ku, MD, Jeffrey S. Painter, BS, Zou JianXiang, MD, Todd D. Edwards, MD, Djeu Y. Julie, PhD, Moscinski C. Lynn, MD, Thomas P. Loughran, MD, Sheng Wei, MD

Blood (2007) 110 (11): 4704.

https://doi.org/10.1182/blood.V110.11.4704.4704

Published: 2007

Journal Articles

Reduced Natural Killer Function Accompanies MDS Disease Progression and Is Restored by Lenalidomide (CC5013, Revlimid®) Via a Mechanism Divergent from Interleukin-2 (IL-2).

P.K. Epling-Burnette, PhD, Fanqi Bai, MD, Jeffrey S. Painter, BS, Rollison Dana, PhD, JianXiang Zou, MD, Edna Ku, MD, Bin Zhong, BS, Sheng Wei, MD, Julie Y. Djeu, PhD, Alan F. List, MD

Blood (2006) 108 (11): 2651.

https://doi.org/10.1182/blood.V108.11.2651.2651

Published: 2006

Journal Articles

Lenalidomide (CC5013, Revlimid®) Promotes T Helper-1 Function Bias and Increases Responsiveness to Autologous Bone Marrow Antigens in Myelodysplastic Syndrome (MDS).

Edna Ku, MD, PhD, JianXiang Zou, MD, Fanqi Bai, MD, Jeffrey S. Painter, BS, Alan F. List, MD, P.K. Epling-Burnette, PhD

Blood (2006) 108 (11): 2659.

https://doi.org/10.1182/blood.V108.11.2659.2659

Published: 2006

Journal Articles

Lenalidomide (CC5013, Revlimid®) Alters a T Cell Homeostatic Check-Point in Patients with Myelodysplastic Syndrome (MDS).

JianXiang Zou, MD, Edna Ku, MD, PhD, Fanqi Bai, MD, Jeffrey S. Painter, BS, Alan F. List, MD, P.K. Epling-Burnette, PhD

Blood (2006) 108 (11): 851.

https://doi.org/10.1182/blood.V108.11.851.851

Published: 2006

Journal Articles

T Large Granular Lymphocyte (LGL) Leukemia Characterized by Expansion of Terminal CD3+/CD8+/CD62L−/CD45RA+ Effector Memory T Cells.

JianXiang Zou, MD, Jeffrey S. Painter, BS, Fanqi Bai, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2006) 108 (11): 4962.

https://doi.org/10.1182/blood.V108.11.4962.4962

Published: 2006

NARROW

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Germline Tissues and DNA Sequencing Analysis Methods for Optimal Somatic Variant Detection in Myelodysplastic Syndrome (MDS)

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

Increased Group B Killer Cell Immunoglobulin-Like Receptor (KIR) Haplotypes with Mismatched MHC Class I and Altered NK Repertoire Distribution in Bone Marrow Failure Syndromes

Autoproliferation Contributes to Clonal Expansion and Changes In Cellular Topography In T Cell Large Granular Lymphocyte (LGL) Leukemia

Phase 2 Multicenter Trial of Rabbit Anti-Thymocyte Serotherapy In Myelodysplastic Syndrome: Rate of Hematological Improvement Associated with Pre-Treatment Disease Duration

Importance of T-Cell Proliferative Stress In Myelodysplastic Syndrome

Genetic Disparities in Killer Cell Immunoglobulin-Like Receptors (KIR) and MHC Class I in Bone Marrow Failure Syndromes

Altered Naive and Memory T Cell Homeostasis and Immunosenescence Characterize Younger Patients with Immunosuppressive-Responsive Myelodysplastic Syndrome

First Clinical Report of Tipifarnib for the Treatment of T-Large Granular Lymphocyte (LGL) Leukemia.

Constitutive Activation of Ras and Mitogen-Activated Protein Kinase (MAPK/ERK) in LGL Leukemia Unrelated to Activating Mutations in N and KRas Genes.

Th2 Polarization Induced by the Farnesyltransferase Inhibitor Tipifarnib (Zarnestra®, R115777) through Suppression of T-bet.

Aberrant NK Receptor Signaling Associated with Large Granular Lymphoycte Leukemia and Primary Pulmonary Hypertension.

Reduced Natural Killer Function Accompanies MDS Disease Progression and Is Restored by Lenalidomide (CC5013, Revlimid®) Via a Mechanism Divergent from Interleukin-2 (IL-2).

Lenalidomide (CC5013, Revlimid®) Promotes T Helper-1 Function Bias and Increases Responsiveness to Autologous Bone Marrow Antigens in Myelodysplastic Syndrome (MDS).

Lenalidomide (CC5013, Revlimid®) Alters a T Cell Homeostatic Check-Point in Patients with Myelodysplastic Syndrome (MDS).

T Large Granular Lymphocyte (LGL) Leukemia Characterized by Expansion of Terminal CD3+/CD8+/CD62L−/CD45RA+ Effector Memory T Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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