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Journal Articles

Discovery of JNJ-88549968, a Novel, First-in-Class CALRmutxCD3 T-Cell Redirecting Antibody for the Treatment of Myeloproliferative Neoplasms

Anna Kuchnio, Elsie Samakai, Eva Hug, Meritxell Balmaña, Lut Janssen, Ricardo Amorim, Ivo Cornelissen, Andrea Majoros, Michaël Broux, Isha Taneja, Vince Torti, Azra Agic, Stefan Moritsch, Filippo Benedetti, Felix Rosebrock, Kathryn Packman, Janine Arts, Sonal Patel, Oliver Christopher Lomas, M. Phillip Deyoung, Oleh Zagrijtschuk, Yusri Elsayed, Stefan Constantinescu, Robert Kralovics, Ulrike Philippar
Journal: Blood
Blood (2023) 142 (Supplement 1): 1777.
https://doi.org/10.1182/blood-2023-173430
Published: 2023
Journal Articles

Inhibition of the Human Double Minute (HDM)-2 E3 Ubiquitin Ligase Activates Different Programmed Cell Death (PCD) Pathways in Models of Non-Hodgkin Lymphoma (NHL) with Wild Type (wt) and Mutant (mut) p53

Richard Julian Jones, PhD, Janine Arts, PhD, Robert Z Orlowski, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3618.
https://doi.org/10.1182/blood.V112.11.3618.3618
Published: 2008
Journal Articles

Antileukemia Activity of JNJ-26481585, a Potent Second-Generation Histone Deacetylase Inhibitor

Weigang Tong, M.D., Ph.D., Yue Wei, Ph.D., William Stevenson, M.D., Ph.D., Shao-Qing Kuang, M.D., Ph.D., Janine Arts, Ph.D., Guillermo Garcia-Manero, M.D.
Journal: Blood
Blood (2008) 112 (11): 2631.
https://doi.org/10.1182/blood.V112.11.2631.2631
Published: 2008
Journal Articles

Novel, 2 ND Generation Histone Deacetylase (HDAC) Inhibitor JNJ-26481585 Exhibits Potent Antitumor Activity Against Chronic Lymphocytic Leukemia Cells In-Vitro and Ex-Vivo .

Kurt Bommert, PhD, Stefan Knop, MD, Janine Arts, PhD, Peter King, PhD, Martin Page, PhD, Eugen Leo, MD, PhD, Ralf Bargou, MD
Journal: Blood
Blood (2007) 110 (11): 4679.
https://doi.org/10.1182/blood.V110.11.4679.4679
Published: 2007