1-20 of 58
James C Mulloy, PhD
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

The Role of LAMP5 in Innate Immune Signaling Is Critical for the Survival of MLL Leukemias

Gabriel Gracia-Maldonado, BS, Jason Clark, MS, Philippe Pierre, PhD, James C. Mulloy, PhD, Ashish R Kumar, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3900.
https://doi.org/10.1182/blood-2018-99-120190
Published: 2018
Journal Articles

Proton Sensor GPR68 Is Essential to Maintain Myeloid Malignancies

Xiaofei He, B.S., Mark Wunderlich, MS, Benjamin Mizukawa, MD, James C. Mulloy, PhD, Saran Feng, MD, PhD, Lauren Lawley, B.S., Caleb Hawkins, B.S., Wenxin Fan, B.S., Guokun Zhou, PhD, Xiang-ming Zha, PhD, Jiajia Zhang, PhD, Johnie Hodge, MD,PhD, Daping Fan, PhD, Stephanie Halene, MD, Jing Fang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1353.
https://doi.org/10.1182/blood-2018-99-110399
Published: 2018
Journal Articles

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Xi Jiang, PhD, Chao Hu, Kyle Ferchen, Ji Nie, Xiaolong Cui, Chih-Hong Chen, PhD, Liting Cheng, Zhixiang Zuo, PhD, William Seibel, PhD, Chunjiang He, PhD, Yixuan Tang, Jennifer R Skibbe, Mark Wunderlich, MS, William C Reinhold, Lei Dong, PhD, Chao Shen, PhD, Stephen Arnovitz, Bryan Ulrich, Jiuwei Lu, PhD, Hengyou Weng, PhD, Rui Su, PhD, Huilin Huang, PhD, Yungui Wang, PhD, Chenying Li, MD, Xi Qin, James C. Mulloy, PhD, Yi Zheng, PhD, Jiajie Diao, PhD, Jie Jin, Chong Li, PhD, Paul P Liu, MD, Chuan He, PhD, Yuan Chen, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 857.
https://doi.org/10.1182/blood.V130.Suppl_1.857.857
Published: 2017
Journal Articles

PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of B-Cell Acute Lymphoblastic Leukemia

Mark Wunderlich, MS, Nicole Manning, Christina Sexton, Perentesis P John, MD, Benjamin Mizukawa, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1318.
https://doi.org/10.1182/blood.V130.Suppl_1.1318.1318
Published: 2017
Journal Articles

LAMP5 - a Novel Target of MLL-Fusion Proteins Is Required for the Propagation of Leukemia

Gabriel Gracia-Maldonado, Jason Clark, James C. Mulloy, PhD, Ashish R Kumar, MBBS, PhD
Journal: Blood
Blood (2016) 128 (22): 1512.
https://doi.org/10.1182/blood.V128.22.1512.1512
Published: 2016
Journal Articles

Molecular Analysis and In Vivo Efficacy Studies on a Novel Chemical-Series of FLT3 Inhibitors in Human FLT3-ITD AML

Katelyn Melgar, MacKenzie Walker, Jiang-kang Jiang, Kelli Wison, Kwangmin Choi, PhD, James C. Mulloy, PhD, Craig J Thomas, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2016) 128 (22): 36.
https://doi.org/10.1182/blood.V128.22.36.36
Published: 2016
Journal Articles

A Xenograft Model of Lymphocyte-Independent, Effector-Driven Macrophage Activation SyndRome Amenable to Anti-CD33 and Anti-IL-6R Treatment

Mark Wunderlich, MS, Courtney Stockman, Mahima Devarajan, Navin Ravishankar, Christina Sexton, Ashish R Kumar, MBBS, PhD, Benjamin Mizukawa, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2016) 128 (22): 3684.
https://doi.org/10.1182/blood.V128.22.3684.3684
Published: 2016
Journal Articles

Loss of Function RUNX1 Mutations Restrict Protein Biosynthesis during Pre-Leukemia and MDS Transition but Not after Leukemic Transformation

Xiongwei Cai, PhD, Yoshihiro Hayashi, MD PhD, Mark Wunderlich, MS, Nancy A. Speck, PhD, James C. Mulloy, PhD, Gang Huang, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2016) 128 (22): 3860.
https://doi.org/10.1182/blood.V128.22.3860.3860
Published: 2016
Journal Articles

The Transcriptome Heterogeneity of MLL-Fusion ALL Is Driven By Fusion Partners Via Distinct Chromatin Binding

Shan Lin, Anetta Ptasinska, PhD, Salam Adli Assi, Jon Kerry, Ruhikanta A. Meetei, PhD, Roger T. Luo, PhD, Michael J. Thirman, MD, Thomas Milne, PhD, Constanze Bonifer, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2016) 128 (22): 576.
https://doi.org/10.1182/blood.V128.22.576.576
Published: 2016
Journal Articles

Inhibition of Impdh As an Effective Treatment for MLL-Fusion Leukemia

Susumu Goyama, MD PhD, Shiori Shikata, Yasutaka Hayashi, Yuto Izawa, Janet Schibler, Hiroyuki Iwamura, Dphil, Motoki Saito, PhD, Satoshi Kofuji, Kazutaka Sumita, Atsuo T Sasaki, James C. Mulloy, PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2016) 128 (22): 750.
https://doi.org/10.1182/blood.V128.22.750.750
Published: 2016
Journal Articles

Protease-Activated Receptor 1 (PAR-1) Inhibits Proliferation but Enhances Leukemia Stem Cell Activity in Acute Myeloid Leukemia

Susumu Goyama, MD PhD, Mahesh Shrestha, Janet Schibler, Leah Rosenfeldt, Whitney Miller, Eric O'Brien, Benjamin Mizukawa, MD, Toshio Kitamura, MD PhD, Joseph S. Palumbo, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2016) 128 (22): 2730.
https://doi.org/10.1182/blood.V128.22.2730.2730
Published: 2016
Journal Articles

Novel Small Molecule FLT3 Inhibitors for the Treatment of FLT3-ITD AML

Katelyn Melgar, MacKenzie Walker, Jian-kang Jiang, PhD, Kelli Wilson, PhD, James C. Mulloy, PhD, Craig J Thomas, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2015) 126 (23): 3690.
https://doi.org/10.1182/blood.V126.23.3690.3690
Published: 2015
Journal Articles

MBNL1 As a New Therapeutic Target in MLL-Fusion Gene Leukemia

Svetlana S Itskovich, PhD, Jason Clark, James C. Mulloy, PhD, Matthew D Disney, Ashish R Kumar, MBBS, PhD
Journal: Blood
Blood (2015) 126 (23): 462.
https://doi.org/10.1182/blood.V126.23.462.462
Published: 2015
Journal Articles

Lymphoid Lineage Preference of MLL-AF4 Is Revealed in a Species-Specific Model

Shan Lin, Roger T. Luo, PhD, Mark Wunderlich, MS, Joseph J. Kaberlein, Ahmad Rayes, MDMSc, John Anastasi, MD, Maureen M O'Brien, MD, James C. Mulloy, PhD, Michael J. Thirman, MD
Journal: Blood
Blood (2015) 126 (23): 2454.
https://doi.org/10.1182/blood.V126.23.2454.2454
Published: 2015
Journal Articles

RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development

Xiaomei Yan, MD PhD, Yoshihiro Hayashi, MD PhD, Xinghui Zhao, PhD, Aili Chen, PhD, Yue Zhang, MD, Fuhong He, Yunzhu Dong, Yalan Rao, PhD, Bo Li, Rajeana Conway, Alba Maiques-Díaz, Nuomin Huang, Shannon E Elf, Johannes Zuber, MD, Zhijian Xiao, MD, William Tse, Daniel G. Tenen, MD, Qianfei Wang, Wei Chen, James C. Mulloy, PhD, Stephen D Nimer, MD, Gang Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 2187.
https://doi.org/10.1182/blood.V124.21.2187.2187
Published: 2014
Journal Articles

Tumor Suppressor FOXO1 Serves As a Critical Oncogenic Mediator in AML1-ETO Leukemia

Shan Lin, Jinsong Zhang, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2014) 124 (21): 264.
https://doi.org/10.1182/blood.V124.21.264.264
Published: 2014
Journal Articles

Maintenance Of Bone Marrow Residency and Self-Renewal Of Leukemic Stem Cells By Cdc42 Gtpase

Benjamin Mizukawa, MD, Eric O'Brien, BS, Wei Liu, MD, PhD, Daniel Moriera Ridsdale, MD, Mark Wunderlich, MS, Yi Zheng, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2013) 122 (21): 2889.
https://doi.org/10.1182/blood.V122.21.2889.2889
Published: 2013
Journal Articles

Acute Lymphoblastic Leukemia Is a Bcl-2 Dependent Disease: Proteomic Profiling and Pre-Clinical Efficacy Of a Selective Bcl-2 Antagonist ABT-199

Marina Konopleva, MD, PhD, Juliana M Benito, PhD, Karine G. Harutyunyan, PhD, Isabel Marzo, LaKiesha Debose, Oscar Gonzalo, Ping Zhou, Rodrigo Jacamo, PhD, Eugene Park, Markus Muschen, MD, PhD, James C. Mulloy, PhD, Linda J Bendall, BSc, PhD, Patrick A Zweidler-McKay, MD, PhD, Kevin R. Coombes, PhD, Yihua Qiu, MD, Nianxiang Zhang, PhD, Joel Leverson, PhD, Deborah A. Thomas, MD, Susan O'Brien, MD, Hagop M. Kantarjian, MD, Steven M. Kornblau, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3919.
https://doi.org/10.1182/blood.V122.21.3919.3919
Published: 2013
Journal Articles

CD3 Antibody Treatment Prevents Gvhd and Allows For Rapid, Long Term, Multilineage Engraftment Of Unfractionated UCB Into Immunodeficient Mice

Mark Wunderlich, MS, Ryan Brooks, Garrett Rhyasen, BSc, James C. Mulloy, PhD
Journal: Blood
Blood (2013) 122 (21): 2018.
https://doi.org/10.1182/blood.V122.21.2018.2018
Published: 2013
Journal Articles

NSGS Mice Develop a Progressive, Myeloid Cell Dependent Aplastic Anemia and Bone Marrow Failure Upon Engraftment With Human Umbilical Cord Blood CD34+ Cells

Mark Wunderlich, MS, Christina Sexton, Benjamin Mizukawa, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2013) 122 (21): 3716.
https://doi.org/10.1182/blood.V122.21.3716.3716
Published: 2013