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Jacob G. Scott
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Journal Articles

Using Gene Therapy to Solve Challenges with CAR-T Cell Immunotherapy: Lead Selection and Preclinical Development of an Adeno-Associated Virus with Reduced Immunogenicity Exhibiting Efficient and Long-Term Expression of an Anti-CD19 T-Cell Engager

Mark A Currier, Allen Reha, Brian Hutzen, Pin-Yi Wang, Chun-yu Chen, Andrea Glaspell, Siddhi Nath Paudel, Akila S Venkataramany, Debashree Das, Danielle Hanlon, Allan A. Kaspar, Samit Varma, Brian K. Kaspar, Jacob G. Scott, Pablo Morales, Peter Ralph, Tonny Johnson, Tania L. Weiss, Timothy P Cripe
Journal: Blood
Blood (2024) 144 (Supplement 1): 1056.
https://doi.org/10.1182/blood-2024-198463
Published: 2024
Journal Articles

Unraveling Immunogenomic Features Germane to Pathobiology of Myelodysplastic Syndromes

Arda Durmaz, Zachary Brady, Kartik Lakhotiya, Benjamin Kroger, Hussein Awada, Yasuo Kubota, Jacky Chen, Colin Hercus, Sébastien Hergalant, Carlos Bravo-Perez, Maria Teresa Voso, Li Lily Wang, Jacob G. Scott, Hetty E. Carraway, Valeria Visconte, Stephen Chung, Simona Pagliuca, Jaroslaw Maciejewski, Carmelo Gurnari
Journal: Blood
Blood (2024) 144 (Supplement 1): 2224.
https://doi.org/10.1182/blood-2024-198530
Published: 2024
Journal Articles

Novel Machine Learning Approaches Tailored to Protein Configuration Predict Drug Vulnerabilities in Myeloid Neoplasia

Arda Durmaz, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Luca Guarnera, Serhan Unlu, Hussein Awada, Praveena Thiagarajan, Yuriy Fedorov, Drew Adams, Carmelo Gurnari, Jacob G. Scott, Jaroslaw Maciejewski, Valeria Visconte
Journal: Blood
Blood (2024) 144 (Supplement 1): 4980.
https://doi.org/10.1182/blood-2024-208903
Published: 2024
Journal Articles

Machine learning demonstrates that somatic mutations imprint invariant morphologic features in myelodysplastic syndromes

Yasunobu Nagata, Ran Zhao, Hassan Awada, Cassandra M. Kerr, Inom Mirzaev, Sunisa Kongkiatkamon, Aziz Nazha, Hideki Makishima, Tomas Radivoyevitch, Jacob G. Scott, Mikkael A. Sekeres, Brian P. Hobbs, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2020) 136 (20): 2249–2262.
https://doi.org/10.1182/blood.2020005488
Published: 2020
Includes: Supplemental data