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Journal Articles

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Kristopher D Marjon, PhD, James Y Chen, MD PhD, Jiaqi Duan, MS, Timothy S Choi, BS, Kavitha Sompalli, MS, Dongdong Feng, PhD, Ofelia Mata, Sharline Chen, B.S., Leslie Kean, MD PhD, Mwe Mwe Chao, MD, Mark Chao, MD PhD, Chris H Takimoto, MD PhD, Balaji Agoram, PhD, Cynthia E. Dunbar, MD, Ravi Majeti, MD PhD, Irving L Weissman, MD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2019) 134 (Supplement_1): 4428.

https://doi.org/10.1182/blood-2019-131490

Published: 2019

Journal Articles

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

Rajni Agarwal, MD, Christopher C. Dvorak, MD, Hye-Sook Kwon, PhD, Janel R Long-Boyle, PharmD, PhD, Susan S Prohaska, PhD MS, Janice W Brown, MD, Anne Le, Alyssa Guttman-Klein, Irving L Weissman, MD, Morton J Cowan, MD, Aaron C. Logan, MD PhD, Kenneth I. Weinberg, MD, Robertson Parkman, MD, Maria-Grazia Roncarolo, MD, Judith A Shizuru, MD PhD

Blood (2019) 134 (Supplement_1): 800.

https://doi.org/10.1182/blood-2019-126239

Published: 2019

Journal Articles

Combination Treatment with 5F9 and Azacitidine Enhances Phagocytic Elimination of Acute Myeloid Leukemia

Dongdong Feng, PhD, Phung Gip, PhD, Kelly Marie McKenna, BS, Feifei Zhao, Ofelia Mata, Timothy S Choi, BS, Jiaqi Duan, MS, Kavitha Sompalli, MS, Ravi Majeti, MD PhD, Irving L Weissman, MD, Chris H Takimoto, MD PhD, Mark Ping Chao, MD PhD, James Y Chen, MD PhD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2018) 132 (Supplement 1): 2729.

https://doi.org/10.1182/blood-2018-99-120170

Published: 2018

Journal Articles

RBC-Specific CD47 Pruning Confers Protection and Underlies the Transient Anemia in Patients Treated with Anti-CD47 Antibody 5F9

James Y Chen, MD PhD, Kelly Marie McKenna, BS, Timothy S Choi, BS, Jiaqi Duan, MS, Lynette Brown, MSc, Jennifer J Stewart, PhD, Kavitha Sompalli, MS, Paresh Vyas, Stanley Schrier, MD, Ravindra Majeti, MD PhD, Irving L Weissman, MD, Kyle Elrod, BS, Mark Ping Chao, MD PhD, Chris H Takimoto, MD PhD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2018) 132 (Supplement 1): 2327.

https://doi.org/10.1182/blood-2018-99-115674

Published: 2018

Journal Articles

High Resolution Mapping of Human Lymphopoiesis Reveals a Common Lymphoid Progenitor (CLP) Population

Nivedita Shankar Saxena, BA, Kara L. Davis, DO, Matthew Arthur Inlay, PhD BA, Astraea Junger, Yujun Yang, Mark L. Krampf, MS, Beruh Dejene, Garry P. Nolan, Prof, PhD, Irving L Weissman, MD, Kenneth I. Weinberg, MD

Blood (2016) 128 (22): 1473.

https://doi.org/10.1182/blood.V128.22.1473.1473

Published: 2016

Journal Articles

Super Cross-Presentation of Tumor Antigens to Elicit Anti-Lymphoma Immunity By Synthetic Design of an Anti-Phosphatidylserine Bridge Protein

Daniel Corey, MD, Irving L Weissman, MD

Blood (2016) 128 (22): 1844.

https://doi.org/10.1182/blood.V128.22.1844.1844

Published: 2016

Journal Articles

β7 Integrin Regulates Intra-Marrow Trafficking of Hematopoietic Stem Cells

Jodi Murakami, Baohui Xu, Christopher B. Franco, Xingbin Hu, Stephen J. Galli, Irving L Weissman, MD, Ching-Cheng Chen

Blood (2014) 124 (21): 2899.

https://doi.org/10.1182/blood.V124.21.2899.2899

Published: 2014

Journal Articles

Successful Engraftment of Hematopoietic Stem Cells into Immunocompetent Recipients Using Only Anti-CD117 Antibody and CD47 Blockade As Conditioning

Akanksha Chhabra, PhD, Aaron M Ring, MS, Kipp Weiskopf, PhD, Irving L Weissman, MD, Judith A. Shizuru, MD PhD

Blood (2014) 124 (21): 2410.

https://doi.org/10.1182/blood.V124.21.2410.2410

Published: 2014

Journal Articles

Direct SIRPa Blockade Augments Macrophage Responses to Therapeutic Anticancer Antibodies

Kipp Weiskopf, M.Phil, Aaron M Ring, MS, Nan Guo, BS, Peter J Schnorr, Roy Louis Maute, PhD BA, MA, MPhil, Jens-Peter Volkmer, MD, Irving L Weissman, MD

Blood (2014) 124 (21): 2729.

https://doi.org/10.1182/blood.V124.21.2729.2729

Published: 2014

Journal Articles

In Utero Depletion Of Fetal Host Hematopoietic Stem Cells Improves Engraftment Following Neonatal Transplantation In Mice

Chris Derderian, MD, Charmin King, MS, Priya Togarrati, PhD, Agnieszka Czechowicz, MD, PhD, Ninnia Lescano, MS, Damien Reynaud, PhD, Emmanuelle Passegue, PhD, Irving L Weissman, MD, Tippi MacKenzie, MD

Blood (2013) 122 (21): 3240.

https://doi.org/10.1182/blood.V122.21.3240.3240

Published: 2013

Journal Articles

Prospective Isolation Of Human Erythroid Lineage-Committed Progenitors

Yasuo Mori, M.D., Ph.D., Jun Seita, M.D., Ph.D., John V. Pluvinage, James Y. Chen, Irving L. Weissman, MD

Blood (2013) 122 (21): 3418.

https://doi.org/10.1182/blood.V122.21.3418.3418

Published: 2013

Journal Articles

Unexplained Anemia In The Elderly Is Due To An Intrinsic Defect In Hematopoietic Stem Cells

Wendy W. Pang, M.D., Ph.D., John V. Pluvinage, Yasuo Mori, M.D., Ph.D., Elizabeth Price, MD, MPH, Amittha Wickrema, PhD, Oyebimpe Adensina, M.D., Andrew Artz, MD, Irving L. Weissman, MD, Stanley L. Schrier, MD

Blood (2013) 122 (21): 2187.

https://doi.org/10.1182/blood.V122.21.2187.2187

Published: 2013

Journal Articles

The Unique Ontogeny Of Natural Killer Cells As Revealed By Genetic Barcoding In The Nonhuman Primate Model

Chuanfeng Wu, PhD, Jan K. Davidson-Moncada, MD, PhD, Rong Lu, PhD, Brian Li, Allen E. Krouse, Mark E. Metzger, Robert E. Donahue, Irving L. Weissman, MD, Richard Childs, MD, Cynthia E. Dunbar, MD

Blood (2013) 122 (21): 15.

https://doi.org/10.1182/blood.V122.21.15.15

Published: 2013

Journal Articles

Clonal Level Lineage Commitment of Mouse Hematopoietic Stem Cells in Vivo

Rong Lu, PhD, Agnieszka Czechowicz, Jun Seita, Irving L. Weissman, MD

Blood (2012) 120 (21): 27.

https://doi.org/10.1182/blood.V120.21.27.27

Published: 2012

Journal Articles

Role of β7 Integrin in Hematopoietic Stem Cell Trafficking.

Jodi Murakami, Baohui Xu, Christopher B. Franco, Stephen J. Galli, Irving L. Weissman, MD, Ching-Cheng Chen

Blood (2012) 120 (21): 2992.

https://doi.org/10.1182/blood.V120.21.2992.2992

Published: 2012

Journal Articles

CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes

Stephen S. Chung, MD, Wendy W Pang, Ph.D., Gino K. In, MD, Max Jan, PhD, Virginia M. Klimek, M.D., Ari Melnick, MD, Irving L. Weissman, MD, Ravi Majeti, MD, PhD, Christopher Y. Park, MD, PhD

Blood (2012) 120 (21): 210.

https://doi.org/10.1182/blood.V120.21.210.210

Published: 2012

Journal Articles

Anti-CD117 (c-Kit) Monoclonal Antibodies Deplete Human Hematopoietic Stem Cells and Facilitate Their Replacement in Humanized NOD/SCID/IL2Rγ −/− Mice: A Non-Toxic Conditioning Regimen for Allotransplantation

Aaron C. Logan, MD, PhD, Agnieszka Czechowicz, MD, PhD, Benjamin V. Kelley, BS, Theingi M. Thway, PhD, Ivan Magana, Mark R. Krampf, MS, Jessica Poyser, Roger P. Hollis, PhD, Donald B. Kohn, MD, Irving L. Weissman, MD, Judith A. Shizuru, MD, PhD

Blood (2012) 120 (21): 4099.

https://doi.org/10.1182/blood.V120.21.4099.4099

Published: 2012

Journal Articles

Quantitation of Leukemic Stem Cell Populations Predicts Clinical Outcome in Acute Myeloid Leukaemia

Charles F. Craddock, MD PhD, Nicolas Goardon, PhD, Lynn Quek, MD, Sylvie Freeman, MD, PhD, Shamyla Siddique, Manoj Raghavan, Anna Schuh, PhD, David Grimwade, PhD, Robert K Hills, MA, MSc, DPhil, Cassandra Brookes, PhD, Michael Griffiths, PhD, James D. Cavenagh, MD, Ravindra Majeti, MD, PhD, Irving L. Weissman, MD, Alan K Burnett, MD, Paresh Vyas

Blood (2011) 118 (21): 638.

https://doi.org/10.1182/blood.V118.21.638.638

Published: 2011

Journal Articles

Transplantation Conditioning Regimens Induce Different Hematopoietic Stem Cell Differentiation in Mice At the Clonal Level

Rong Lu, PhD, Agnieszka Czechowicz, PhD, Irving L. Weissman, MD

Blood (2011) 118 (21): 140.

https://doi.org/10.1182/blood.V118.21.140.140

Published: 2011

Journal Articles

Characterization of Hematopoietic Stem Cell Frequency and Function In Unexplained Anemia of the Elderly

Wendy Pang, Elizabeth Price, MD, MPH, Irving L. Weissman, MD, Stanley L. Schrier, MD

Blood (2010) 116 (21): 2047.

https://doi.org/10.1182/blood.V116.21.2047.2047

Published: 2010

NARROW

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

Combination Treatment with 5F9 and Azacitidine Enhances Phagocytic Elimination of Acute Myeloid Leukemia

RBC-Specific CD47 Pruning Confers Protection and Underlies the Transient Anemia in Patients Treated with Anti-CD47 Antibody 5F9

High Resolution Mapping of Human Lymphopoiesis Reveals a Common Lymphoid Progenitor (CLP) Population

Super Cross-Presentation of Tumor Antigens to Elicit Anti-Lymphoma Immunity By Synthetic Design of an Anti-Phosphatidylserine Bridge Protein

β7 Integrin Regulates Intra-Marrow Trafficking of Hematopoietic Stem Cells

Successful Engraftment of Hematopoietic Stem Cells into Immunocompetent Recipients Using Only Anti-CD117 Antibody and CD47 Blockade As Conditioning

Direct SIRPa Blockade Augments Macrophage Responses to Therapeutic Anticancer Antibodies

In Utero Depletion Of Fetal Host Hematopoietic Stem Cells Improves Engraftment Following Neonatal Transplantation In Mice

Prospective Isolation Of Human Erythroid Lineage-Committed Progenitors

Unexplained Anemia In The Elderly Is Due To An Intrinsic Defect In Hematopoietic Stem Cells

The Unique Ontogeny Of Natural Killer Cells As Revealed By Genetic Barcoding In The Nonhuman Primate Model

Clonal Level Lineage Commitment of Mouse Hematopoietic Stem Cells in Vivo

Role of β7 Integrin in Hematopoietic Stem Cell Trafficking.

CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes

Anti-CD117 (c-Kit) Monoclonal Antibodies Deplete Human Hematopoietic Stem Cells and Facilitate Their Replacement in Humanized NOD/SCID/IL2Rγ −/− Mice: A Non-Toxic Conditioning Regimen for Allotransplantation

Quantitation of Leukemic Stem Cell Populations Predicts Clinical Outcome in Acute Myeloid Leukaemia

Transplantation Conditioning Regimens Induce Different Hematopoietic Stem Cell Differentiation in Mice At the Clonal Level

Characterization of Hematopoietic Stem Cell Frequency and Function In Unexplained Anemia of the Elderly

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American Society of Hematology

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ASH Publications

American Society of Hematology

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