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Irene Ghobrial, M.D.
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Journal Articles

MicroRNA Changes Occur in Multiple Myeloma Cells in the Context of Bone Marrow Milieu.

Roccaro M. Roccaro, MD, PhD, Antonio Sacco, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Hai Ngo, Molly R Melhem, Phong Quong, Judith M. Runnels, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 1785.
https://doi.org/10.1182/blood.V114.22.1785.1785
Published: 2009
Journal Articles

Primary Waldesntrom Macroglobulinemia Cells Harbor Constitutive Activation of Akt, mTOR, Rictor and Raptor: Rational for Testing a Dual Inhibitor of the PI3K/Akt and mTOR Pathways in This Disease.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Emanuel N. Husu, Costas M Pitsillides, PhD, Steven Vesole, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Molly Melhem, Hai Ngo, Phong Quang, Patricia Maiso, PhD, Judith M. Runnels, PhD, Charles P. Lin, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 3843.
https://doi.org/10.1182/blood.V114.22.3843.3843
Published: 2009
Journal Articles

Cholesterol Regulation and Statin Therapy in Patients with Waldenstrom's Macroglobulinemia.

Thea Ioakimidis, MS, Christopher J Patterson, Zachary Hunter, Jacob Soumerai, Robert Manning, Diane L. Warren, Irene Ghobrial, M.D., Patricia Sheehy, NP, Steven Treon, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 4789.
https://doi.org/10.1182/blood.V114.22.4789.4789
Published: 2009
Journal Articles

Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Monette Aujay, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, PhD, BPharm, Molly Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 4911.
https://doi.org/10.1182/blood.V114.22.4911.4911
Published: 2009
Journal Articles

Carfilzomib Exerts Anti-Neoplastic Activity in Waldenstrom Macroglobulinemia.

Antonio Sacco, Aldo M. Roccaro, MD, PhD, Monette Aujay, PhD, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 4916.
https://doi.org/10.1182/blood.V114.22.4916.4916
Published: 2009
Journal Articles

Lack of Response to Vaccination in MGUS and Stable Myeloma.

Rao H Prabhala, PhD, Yvonne A Efebera, MD, Saem Lee, Andrew J Han, Dheeraj Pelluru, Puru Nanjappa, MS, Samir Amin, Christine Pai, Irene Ghobrial, M.D., Robert L Schlossman, M.D., Ph.D., Jacob Laubach, Mariateresa Fulciniti, Paul Richardson, M.D., Ph.D., Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2009) 114 (22): 1852.
https://doi.org/10.1182/blood.V114.22.1852.1852
Published: 2009
Journal Articles

Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.

Yu-Tzu Tai, PhD, Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Weihua Song, M.D., Peter Burger, B.S., Matthew Rumizen, Teru Hideshima, M.D. Ph.D., Klaus Podar, M.D. Ph.D., Irene Ghobrial, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3460.
https://doi.org/10.1182/blood.V108.11.3460.3460
Published: 2006
Journal Articles

Anti-Tumor Activity of Single-Agent CCI-779 for Relapsed Mantle Cell Lymphoma: A Phase II Trial in the North Central Cancer Treatment Group.

Thomas Witzig, M.D., Susan Geyer, Ph.D., Irene Ghobrial, M.D., David Inwards, M.D., Rafael Fonseca, M.D., Scott Kaufmann, M.D., Ph.D., Paul Kurtin, M.D., Joseph Colgan, M.D., William Morice, M.D., Ph.D., Steven Alberts, M.D., Muhammed Salim, M.D., Kendrith Rowland, M.D., Shaker Dakhil, M.D., Roscoe Morton, M.D., Philip Stella, M.D.
Journal: Blood
Blood (2004) 104 (11): 129.
https://doi.org/10.1182/blood.V104.11.129.129
Published: 2004
Journal Articles

Experimental Design & Analysis of Protein Array Data: Applying Methods from cDNA Arrays.

Jeanette E. Eckel, Ph.D., Antje Hoering, Ph.D., Irene Ghobrial, M.D.
Journal: Blood
Blood (2004) 104 (11): 4280.
https://doi.org/10.1182/blood.V104.11.4280.4280
Published: 2004