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Irène Baccelli
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Journal Articles

CD127-Directed Immunotherapy with Lusvertikimab Outperforms Imatinib in Preclinical ABL-Class-Fusion-Positive BCP-ALL

Anna Dietterle, Julia Heymann, Anna Laqua, Claas Reimer, Denny Takudzwa Mahachi, Carina Lynn Gehlert, Dorothee Winterberg, Maja Kowol, Alexander Arthur Wurm, Philipp Fanter, Denis Pinkle, Dennis Das Gupta, Christian Vokuhl, Jan Philipp Schmid, Matthias Peipp, Martin Schrappe, Irène Baccelli, Nicolas Poirier, Monika Brüggemann, Gunnar Cario, Denis Martin Schewe, Lennart Lenk
Journal: Blood
Blood (2024) 144 (Supplement 1): 636.
https://doi.org/10.1182/blood-2024-205421
Published: 2024
Journal Articles

The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis

Lennart Lenk, Irène Baccelli, Anna Laqua, Julia Heymann, Claas Reimer, Anna Dietterle, Dorothee Winterberg, Caroline Mary, Frédérique Corallo, Julien Taurelle, Emma Narbeburu, Stéphanie Neyton, Mylène Déramé, Sabrina Pengam, Fotini Vogiatzi, Beat Bornhauser, Jean-Pierre Bourquin, Simon Raffel, Vladyslava Dovhan, Thomas Schüler, Gabriele Escherich, Monique L. den Boer, Judith M. Boer, Wiebke Wessels, Matthias Peipp, Julia Alten, Željko Antić, Anke K. Bergmann, Martin Schrappe, Gunnar Cario, Monika Brüggemann, Nicolas Poirier, Denis M. Schewe
Journal: Blood
Blood (2024) 143 (26): 2735–2748.
https://doi.org/10.1182/blood.2023021088
Published: 2024
Includes: Supplemental data
Journal Articles

The IL7R-Antagonist OSE-127 Blocks Acute Lymphoblastic Leukemia Development Via a Dual Mode of Action

Lennart Lenk, Irène Baccelli, Dorothee Winterberg, Anna Dietterle, Frédérique Corallo, Julien Taurelle, Emma Narbeburu, Anna Laqua, Beat Bornhauser, Jean-Pierre Bourquin, Fotini Vogiatzi, Martin Schrappe, Gunnar Cario, Monika Brüggemann, Nicolas Poirier, Denis Martin Schewe
Journal: Blood
Blood (2022) 140 (Supplement 1): 1045–1047.
https://doi.org/10.1182/blood-2022-162261
Published: 2022
Journal Articles

IL7R Targeting Using OSE-127 Shows Robust Anti-Leukemic Activity in B-Cell Precursor Acute Lymphoblastic Leukemia Xenografts

Lennart Lenk, Irène Baccelli, Dorothee Winterberg, Frédérique Corallo, Fotini Vogiatzi, Lea Spory, Martin Schrappe, Gunnar Cario, Anna Laqua, Monika Brüggemann, Nicolas Poirier, Denis Martin Schewe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1313.
https://doi.org/10.1182/blood-2021-150323
Published: 2021
Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Irene Baccelli, PhD, Yves Gareau, Bernhard Lehnertz, PhD, Gingras Stephane, Jean-Francois Spinella, PhD, Alexandre Beautrait, PhD, Sophie Corneau, Nadine Mayotte, Isabel Boivin, Simon Girard, Tara MacRae, Melanie Frechette, Koryne Leveille, Jana Krosl, PhD, Clarisse Thiollier, PhD, Evgeny Kanshin, PhD, Thierry Bertomeu, PhD, Jasmin Coulombe-Huntington, Corinne St-Denis, Marie-Eve Bordeleau, PhD, Geneviève Boucher, Philippe P Roux, PhD, Sébastien Lemieux, PhD, Mike Tyers, PhD, Pierre Thibault, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 910.
https://doi.org/10.1182/blood-2018-99-114525
Published: 2018