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Journal Articles

Pharmacodynamics and Biomarker Correlates of Imvotamab (IGM-2323), the First-in-Class CD20xCD3 Bispecific IgM Antibody with Dual Mechanisms of Action, in Patients with Advanced B Cell Malignancies

Genevive H. Hernandez, John So, Kathryn A. Logronio, Maya F. Kotturi, Won Seog Kim, Philippe Armand, Chan Y. Cheah, Ajay K. Gopal, Ian W. Flinn, Gareth P. Gregory, Matthew J. Matasar, Loretta J. Nastoupil, Catherine S. Diefenbach, Sung-Soo Yoon, Matthew Ku, Ibrahim Qazi, Maya K. Leabman, Iris Sison, Bruce A. Keyt, Chris H. Takimoto, Thomas J. Manley, Elizabeth L. Budde
Journal: Blood
Blood (2022) 140 (Supplement 1): 6436–6438.
https://doi.org/10.1182/blood-2022-163235
Published: 2022
Journal Articles

The First-in-Class Anti-CD47 Antibody Magrolimab (5F9) in Combination with Azacitidine Is Effective in MDS and AML Patients: Ongoing Phase 1b Results

David A Sallman, MD, Adam S. Asch, MD, Monzr M. Al Malki, MD, Daniel J. Lee, MD, William B. Donnellan, MD, Guido Marcucci, MD, Suman Kambhampati, MD, Naval G. Daver, MD, Guillermo Garcia-Manero, MD, Rami S. Komrokji, MD, Joanna Van Elk, Ming Lin, PhD, Jens-Peter Volkmer, MD, Chris H Takimoto, MD PhD, Mark Chao, MD PhD, Paresh Vyas, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 569.
https://doi.org/10.1182/blood-2019-126271
Published: 2019
Journal Articles

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Kristopher D Marjon, PhD, James Y Chen, MD PhD, Jiaqi Duan, MS, Timothy S Choi, BS, Kavitha Sompalli, MS, Dongdong Feng, PhD, Ofelia Mata, Sharline Chen, B.S., Leslie Kean, MD PhD, Mwe Mwe Chao, MD, Mark Chao, MD PhD, Chris H Takimoto, MD PhD, Balaji Agoram, PhD, Cynthia E. Dunbar, MD, Ravi Majeti, MD PhD, Irving L Weissman, MD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4428.
https://doi.org/10.1182/blood-2019-131490
Published: 2019
Journal Articles

Translational Study of Cell Surface Proteins in Non-Hodgkin Lymphoma Patients Treated with the First-in-Class Anti-CD47 Antibody Magrolimab (5F9) in Combination with Rituximab

Roy Louis Maute, PhD, James Y Chen, MD PhD, Kristopher David Marjon, PhD, Jiaqi Duan, MS, Timothy Choi, BA, Mark Chao, MD PhD, Chris H Takimoto, MD PhD, Balaji Agoram, PhD, Jens-Peter Volkmer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5229.
https://doi.org/10.1182/blood-2019-127526
Published: 2019
Journal Articles

RBC-Specific CD47 Pruning Confers Protection and Underlies the Transient Anemia in Patients Treated with Anti-CD47 Antibody 5F9

James Y Chen, MD PhD, Kelly Marie McKenna, BS, Timothy S Choi, BS, Jiaqi Duan, MS, Lynette Brown, MSc, Jennifer J Stewart, PhD, Kavitha Sompalli, MS, Paresh Vyas, Stanley Schrier, MD, Ravindra Majeti, MD PhD, Irving L Weissman, MD, Kyle Elrod, BS, Mark Ping Chao, MD PhD, Chris H Takimoto, MD PhD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2327.
https://doi.org/10.1182/blood-2018-99-115674
Published: 2018
Journal Articles

Combination Treatment with 5F9 and Azacitidine Enhances Phagocytic Elimination of Acute Myeloid Leukemia

Dongdong Feng, PhD, Phung Gip, PhD, Kelly Marie McKenna, BS, Feifei Zhao, Ofelia Mata, Timothy S Choi, BS, Jiaqi Duan, MS, Kavitha Sompalli, MS, Ravi Majeti, MD PhD, Irving L Weissman, MD, Chris H Takimoto, MD PhD, Mark Ping Chao, MD PhD, James Y Chen, MD PhD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2729.
https://doi.org/10.1182/blood-2018-99-120170
Published: 2018
Journal Articles

Pharmacokinetics and Safety of Bortezomib In Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction: Results of the Phase 1 National Cancer Institute Organ Dysfunction Working Group Study NCI 6432

Karthik Venkatakrishnan, Ramesh K Ramanathan, John Sarantopoulos, Daniel L Mulkerin, Stephen I Shibata, Anne Hamilton, Afshin Dowlati, Sridhar Mani, Michelle A Rudek, Percy Ivy, Chris H Takimoto, Rachel Neuwirth, Sudha Parasuraman, Patricia M LoRusso
Journal: Blood
Blood (2010) 116 (21): 3975.
https://doi.org/10.1182/blood.V116.21.3975.3975
Published: 2010
Journal Articles

CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein

A Suzuki, DP Andrew, JA Gonzalo, M Fukumoto, J Spellberg, M Hashiyama, H Takimoto, N Gerwin, I Webb, G Molineux, R Amakawa, Y Tada, A Wakeham, J Brown, I McNiece, K Ley, EC Butcher, T Suda, JC Gutierrez-Ramos, TW Mak
Journal: Blood
Blood (1996) 87 (9): 3550–3562.
https://doi.org/10.1182/blood.V87.9.3550.bloodjournal8793550
Published: 1996