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Journal Articles

Expression of PIM Kinases in Reed-Sternberg Cells Fosters Immune Privilege and Tumor Cell Survival in Classical Hodgkin Lymphoma

Maciej Szydlowski, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Grazyna Hoser, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Anna Polak, MSc, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Krzysztof Warzocha, MD PhD, Jan Maciej Zaucha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 819.

https://doi.org/10.1182/blood.V126.23.819.819

Published: 2015

Journal Articles

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD PhD, Katherine Sullivan, Paulina Podszywalow-Bartnicka, Grazyna Hoser, PhD, Elisabeth Bolton-Gillespie, Kimberly Cramer-Morales, Artur Slupianek, PhD, Chun Zhou, PhD, Sabine Cerny-Reiterer, DVM, Tomasz Stoklosa, MD PhD, Stephen M. Sykes, PhD, Peter Valent, MD, Curt I. Civin, MD, Markus Muschen, MD PhD, Mark D. Minden, MD PhD, Kolja Eppert, PhD, Tomasz Skorski, MD PhD

Blood (2014) 124 (21): 480.

https://doi.org/10.1182/blood.V124.21.480.480

Published: 2014

Journal Articles

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

Yashodhara Dasgupta, Mateusz Koptyra, PhD, Margaret Nieborowska-Skorska, MD, PhD, Elisabeth Bolton Gillespie, PhD, Tomasz Stoklosa, MD, PhD, Grazyna Hoser, PhD, Mariusz Wasik, MD, Markus Muschen, Christine Richardson, PhD, Tomasz Skorski, MD, PhD

Blood (2013) 122 (21): 1466.

https://doi.org/10.1182/blood.V122.21.1466.1466

Published: 2013

Journal Articles

Oncogene-Induced DNA Repair Defects Promote PARP1-Mediated “Dual Synthetic Lethality” To Eradicate Quiescent and Proliferating Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD, PhD, Artur Slupianek, PhD, Grazyna Hoser, PhD, Elisabeth Bolton-Gillespie, PhD, Alexei Tulin, Sabine Cerny-Reiterer, D.V.M, Peter Valent, Markus Muschen, Stephen M. Sykes, PhD, Tomasz Skorski, MD, PhD

Blood (2013) 122 (21): 810.

https://doi.org/10.1182/blood.V122.21.810.810

Published: 2013

Journal Articles

Genomic Instability in CML-CP originates From the Most Primitive Imatinib-Refractory Leukemia Stem Cells

Elisabeth Bolton, Mirle Schemionek, PhD, Hans-Urlich Klein, Grazyna Hoser, PhD, Sylwia Flis, Thoralf Lange, Linda Kerstiens, Margaret Nieborowska-Skorska, MD, PhD, Martin C. Müller, MD, Hardik Modi, Ravi Bhatia, MD, Steffen Koschmieder, MD, Tomasz Skorski, MD, PhD

Blood (2012) 120 (21): 909.

https://doi.org/10.1182/blood.V120.21.909.909

Published: 2012

Journal Articles

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

Blood (2011) 118 (21): 2736.

https://doi.org/10.1182/blood.V118.21.2736.2736

Published: 2011

Journal Articles

Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.

Piotr Kopinski, Margaret Nieborowska-Skorska, MD, PhD, Grazyna Hoser, PhD, Danielle Ngaba, Regina Ray, Mateusz Koptyra, PhD, Elisabeth Bolton, Ilona Seferynska, MD, PhD, Tomasz Stoklosa, MD, PhD, Artur Slupianek, PhD, Mamatha R. Reddy, Martin Sattler, PhD, Tomasz Skorski, MD, PhD

Blood (2010) 116 (21): 1211.

https://doi.org/10.1182/blood.V116.21.1211.1211

Published: 2010

Journal Articles

BCR/ABL Requires Fanconi Anemia D2 (FANCD2) Protein to Transform Hematopoetic Stem Cells.

Tomasz Stoklosa, MD, PhD, Mateusz Koptyra, PhD, Grazyna Hoser, PhD, Ilona Seferynska, MD, PhD, Eliza Glodkowska, MD, Tomasz Skorski, MD, PhD

Blood (2009) 114 (22): 3249.

https://doi.org/10.1182/blood.V114.22.3249.3249

Published: 2009

Journal Articles

ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial Respiratory Chain Complex III.

Margaret Nieborowska-Skorska, Ph.D., Mateusz Koptyra, PhD, Elisabeth Bolton, Regina Ray, Danielle Ngaba, Grazyna Hoser, PhD, Tomasz Stoklosa, M.D., Ph.D., Artur Slupianek, PhD, Piotr Kopinski, Tomasz Skorski, MD, PhD

Blood (2009) 114 (22): 3268.

https://doi.org/10.1182/blood.V114.22.3268.3268

Published: 2009

Journal Articles

Monoubiquitination of the Fanconi Anemia D2 (FANCD2) Protein Regulates the Transforming Potential of BCR/ABL

Mateusz Koptyra, PhD, Tomasz Stoklosa, MD, PhD, Grazyna Hoser, PhD, Ilona Seferynska, MD, PhD, Eliza Glodkowska, MD, Tomasz Skorski, MD, PhD

Blood (2008) 112 (11): 3189.

https://doi.org/10.1182/blood.V112.11.3189.3189

Published: 2008

Journal Articles

Mechanisms Generating free Radicals in CML Stem/Progenitor Cell Populations Causing DNA Damage and Genomic Instability

Margaret Nieborowska-Skorska, MD, PhD, Mateusz Koptyra, PhD, Grazyna Hoser, PhD, Regina Ray, Danielle Ngaba, Elisabeth Bolton, Tomasz Skorski, MD, PhD

Blood (2008) 112 (11): 192.

https://doi.org/10.1182/blood.V112.11.192.192

Published: 2008

Journal Articles

BCR/ABL→STAT5 Pathway Stimulates Helix-Loop-Helix Id-1 Protein To Enhance the MMP9 - Dependent Invasiveness of Leukemia Cells.

Margaret Nieborowska-Skorska, MD, PhD, Grazyna Hoser, PhD, Maciej Malecki, PhD, Mariusz Wasik, MD, PhD, Tomasz Skorski, MD, PhD

Blood (2004) 104 (11): 2954.

https://doi.org/10.1182/blood.V104.11.2954.2954

Published: 2004

NARROW

Expression of PIM Kinases in Reed-Sternberg Cells Fosters Immune Privilege and Tumor Cell Survival in Classical Hodgkin Lymphoma

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

Oncogene-Induced DNA Repair Defects Promote PARP1-Mediated “Dual Synthetic Lethality” To Eradicate Quiescent and Proliferating Leukemia Stem and Progenitor Cells

Genomic Instability in CML-CP originates From the Most Primitive Imatinib-Refractory Leukemia Stem Cells

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.

BCR/ABL Requires Fanconi Anemia D2 (FANCD2) Protein to Transform Hematopoetic Stem Cells.

ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial Respiratory Chain Complex III.

Monoubiquitination of the Fanconi Anemia D2 (FANCD2) Protein Regulates the Transforming Potential of BCR/ABL

Mechanisms Generating free Radicals in CML Stem/Progenitor Cell Populations Causing DNA Damage and Genomic Instability

BCR/ABL→STAT5 Pathway Stimulates Helix-Loop-Helix Id-1 Protein To Enhance the MMP9 - Dependent Invasiveness of Leukemia Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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