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Journal Articles

MLL-USP2 : An Underestimated New Entity of MLL -Rearranged Leukemia Identified By NGS Analysis

Claus Meyer, PhD, Bruno Lopes, PhD, Aurélie Caye-Eude, PharmD, Hélène Cavé, PharmD, PhD, Chloé Arfeuille, PhD, Rosemary Sutton, PhD, Nicola Venn, BSc, Patrizia Larghero, PhD, Seung Hwan Oh, MD, Grigory Tsaur, MD PhD, Marketa Zaliova, Jan Zuna, Vesa Juvonen, PhD, Renate Panzer-Grümayer, MD, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD, Mariana Emerenciano, PhD, Rolf Marschalek, PhD

Blood (2018) 132 (Supplement 1): 3920.

https://doi.org/10.1182/blood-2018-99-112594

Published: 2018

Journal Articles

Successful of Chemo-Free Treatment with Dasatinib and Blinatumomab in a Pediatric EBF1-PDGFRβ Positive Acute Lymphoblastic Leukemia

Fara Petruzziello, MD, Giovanna Giagnuolo, MD, Giovanni Cazzaniga, PhD, Giuliana Beneduce, MD, Franco Locatelli, Pio Stellato, MD, Grazia Fazio, PhD, Giuseppe Mirabelli, PhD, Giuseppe Menna, MD, Rosanna Parasole, MD

Blood (2018) 132 (Supplement 1): 5213.

https://doi.org/10.1182/blood-2018-99-113829

Published: 2018

Journal Articles

Clinical-Grade Transduction of Allogeneic Cytokine Induced Killer (CIK) Cells with CD19 Chimeric Antigen Receptor (CAR) Using Sleeping Beauty (SB) Transposon: Successful GMP-Compliant Manufacturing for Clinical Applications

Blood (2018) 132 (Supplement 1): 196.

https://doi.org/10.1182/blood-2018-196

Published: 2018

Journal Articles

Distinct MiR-126 Expression Describes a Non-Genetic but Functional Intra-Tumoral Heterogeneity in Primary Human B-ALL and Can be Prospectively Used to Identify Aggressive Subclones in NSG Mice

Carolina Caserta, MS, Matteo Maria Naldini, MD, Silvia Nucera, MD, Davide Cittaro, Giacomo Desantis, Francesca Pavesi, MD, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2017) 130 (Supplement 1): 35.

https://doi.org/10.1182/blood.V130.Suppl_1.35.35

Published: 2017

Journal Articles

Sleeping Beauty Modified CAR+ Lymphocytes Engraft and Exhibit Anti-Tumor Activity in Patient-Derived Xenograft Models of Acute Lymphoblastic Leukemia

Chiara F. Magnani, PhD, Claudia Mezzanotte, Claudia Cappuzzello, PhD, Fabrizio Benedicenti, Michela Bardini, PhD, Sarah Tettamanti, PhD, Grazia Fazio, PhD, Gianni Cazzaniga, PhD, Laurence J.N. Cooper, MD PhD, Eugenio Montini, PhD, Andrea Biondi, MD, Ettore Biagi, MD PhD

Blood (2016) 128 (22): 4022.

https://doi.org/10.1182/blood.V128.22.4022.4022

Published: 2016

Journal Articles

A Versatile DNA/RNA NGS Targeted Capture Strategy for Detection of Fusion Genes in Pediatric ALL

Grazia Fazio, PhD, Andrea Grioni, Tomas Reigl, Silvia Rigamonti, Vojtech Bystry, Simona Songia, Andrea Biondi, MD, Nikos Darzentas, Giovanni Cazzaniga, PhD

Blood (2016) 128 (22): 2913.

https://doi.org/10.1182/blood.V128.22.2913.2913

Published: 2016

Journal Articles

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Angela Maria Savino, Jolanda Sarno, Luca Trentin, Margherita Vieri, Grazia Fazio, PhD, Michela Bardini, Cristina Bugarin, Gianluca Fossati, Kara L. Davis, DO, Giuseppe Gaipa, PhD, Lueder Hinrich Meyer, MD, Garry P. Nolan, Prof, PhD, Andrea Biondi, Prof, MD, Geertruy Te Kronnie, PhD, Chiara Palmi, PhD, Giovanni Cazzaniga

Blood (2015) 126 (23): 2534.

https://doi.org/10.1182/blood.V126.23.2534.2534

Published: 2015

Journal Articles

Rapid Identification of BCR/ABL1 -like Acute Lymphoblastic Leukemia (ALL) Cases By Quantitative Real Time-PCR (Q-RT-PCR). Generation and Validation of a Predictive Statistical Model

Sabina Chiaretti, Sara Grammatico, Alfonso Piciocchi, Monica Messina, Anna Lucia Fedullo, Valentina Gianfelici, Grazia Fazio, PhD, Nadia Peragine, Maria Paola Martelli, Paola Fazi, Marco Vignetti, Antonella Vitale, Cyril Salek, Gianni Cazzaniga, PhD, Anna Guarini, Robin Foà

Blood (2015) 126 (23): 1410.

https://doi.org/10.1182/blood.V126.23.1410.1410

Published: 2015

Journal Articles

Library Preparation Is the Major Factor Affecting Differences in Results of Immunoglobulin Gene Rearrangements Detection on Two Major Next-Generation Sequencing Platforms

Blood (2015) 126 (23): 1411.

https://doi.org/10.1182/blood.V126.23.1411.1411

Published: 2015

Journal Articles

Clonal Evolution and Lack of BCR-ABL1 Mutations in Pediatric Ph+ ALL Patients Resistant/Refractory to Imatinib Treatment

Valeria Cazzaniga, PhD, Paola De Lorenzo, Federica Mottadelli, Grazia Fazio, PhD, Tiziana Villa, Vincenzo Rossi, Martina Pigazzi, PhD, Marcela B. Mansur, PhD, Marco Zecca, MD, Elena Barisone, MD, Franco Locatelli, MD, Giuseppe Basso, Prof, MD, Maria Grazia Valsecchi, PhD, Mel Greaves, FRS, Andrea Biondi, Prof, MD, Anthony M Ford, Giovanni Cazzaniga

Blood (2015) 126 (23): 2622.

https://doi.org/10.1182/blood.V126.23.2622.2622

Published: 2015

Journal Articles

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression

Valeria Cazzaniga, Marco Giordan, Cristina Bugarin, Chiara Palmi, Angela Savino, Geertruy te Kronnie, Giuseppe Gaipa, Andrea Biondi, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD

Blood (2013) 122 (21): 3738.

https://doi.org/10.1182/blood.V122.21.3738.3738

Published: 2013

Journal Articles

Novel Chimeric Transcripts Involving PAX5 in B-Cell Precursor ALL

Grazia Fazio, PhD, Clelia Tiziana Storlazzi, Marco Severgnini, Valeria Cazzaniga, Luciana Impera, Giulia Daniele, Ilaria Iacobucci, Marta Galbiati, Anna Leszl, Silvia Bungaro, Ingrid Cifola, Gianluca De Bellis, Giovanni Martinelli, Giuseppe Basso, Andrea Biondi, MD, Giovanni Cazzaniga, PhD

Blood (2013) 122 (21): 1367.

https://doi.org/10.1182/blood.V122.21.1367.1367

Published: 2013

Journal Articles

Multivariate Analysis Reveals a miRNA Profile Correlated To Karyotype and Outcome In Pediatric B-Cell Precursor ALL

Marina Lipkin Vasquez, PhD, Stefano Volinia, PhD, Cecilia Fernandez, Nicola Zanesi, PhD, Grazia Fazio, PhD, Ilana Renault Zalcberg, MD, PhD, Ramiro Garzon, MD, Giovanni Cazzaniga, PhD, Andrea Biondi, MD, Carlo M. Croce, MD

Blood (2013) 122 (21): 2597.

https://doi.org/10.1182/blood.V122.21.2597.2597

Published: 2013

Journal Articles

Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience

Geertruy te Kronnie, Daniela Silvestri, Elena Vendramini, Grazia Fazio, PhD, Franco Locatelli, MD, Valentino Conter, Chiara Borga, Maria Grazia Valsecchi, Andrea Biondi, MD, Giuseppe Basso, Giovanni Cazzaniga, PhD

Blood (2013) 122 (21): 353.

https://doi.org/10.1182/blood.V122.21.353.353

Published: 2013

Journal Articles

PAX5/TEL Exhibits a Dominant-Negative Role by Inhibiting the Expression of Genes Involved in BCR Signalling and Suppressing the Binding of Wild Type PAX5 to Its Direct Target Gene CD79A (mb-1) in a human Pre-B ALL Cell Line.

Gabriela B. Iwanski, MD, Nils Heinrich Thoennissen, MD, PohYeen Lor, Norihiko Kawamata, MD, PhD, Daniel Nowak, MD, Grazia Fazio, PhD, Andrea Biondi, MD, Giovanni Gazzaniga, PhD, H. Phillip Koeffler, MD

Blood (2009) 114 (22): 3455.

https://doi.org/10.1182/blood.V114.22.3455.3455

Published: 2009

Journal Articles

PAX5/TEL Causes Down Modulation of B-Lineage Specific Genes, and Enhances Migration to CXCL12 in preBI Cells.

Grazia Fazio, PhD Fellow, Chiara Palmi, PhD Fellow, Antonius G. Rolink, PhD, Giovanni Cazzaniga, PhD, Andrea Biondi, MD

Blood (2007) 110 (11): 980.

https://doi.org/10.1182/blood.V110.11.980.980

Published: 2007

NARROW

MLL-USP2 : An Underestimated New Entity of MLL -Rearranged Leukemia Identified By NGS Analysis

Successful of Chemo-Free Treatment with Dasatinib and Blinatumomab in a Pediatric EBF1-PDGFRβ Positive Acute Lymphoblastic Leukemia

Clinical-Grade Transduction of Allogeneic Cytokine Induced Killer (CIK) Cells with CD19 Chimeric Antigen Receptor (CAR) Using Sleeping Beauty (SB) Transposon: Successful GMP-Compliant Manufacturing for Clinical Applications

Distinct MiR-126 Expression Describes a Non-Genetic but Functional Intra-Tumoral Heterogeneity in Primary Human B-ALL and Can be Prospectively Used to Identify Aggressive Subclones in NSG Mice

Sleeping Beauty Modified CAR+ Lymphocytes Engraft and Exhibit Anti-Tumor Activity in Patient-Derived Xenograft Models of Acute Lymphoblastic Leukemia

A Versatile DNA/RNA NGS Targeted Capture Strategy for Detection of Fusion Genes in Pediatric ALL

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Rapid Identification of BCR/ABL1 -like Acute Lymphoblastic Leukemia (ALL) Cases By Quantitative Real Time-PCR (Q-RT-PCR). Generation and Validation of a Predictive Statistical Model

Library Preparation Is the Major Factor Affecting Differences in Results of Immunoglobulin Gene Rearrangements Detection on Two Major Next-Generation Sequencing Platforms

Clonal Evolution and Lack of BCR-ABL1 Mutations in Pediatric Ph+ ALL Patients Resistant/Refractory to Imatinib Treatment

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression

Novel Chimeric Transcripts Involving PAX5 in B-Cell Precursor ALL

Multivariate Analysis Reveals a miRNA Profile Correlated To Karyotype and Outcome In Pediatric B-Cell Precursor ALL

Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience

PAX5/TEL Exhibits a Dominant-Negative Role by Inhibiting the Expression of Genes Involved in BCR Signalling and Suppressing the Binding of Wild Type PAX5 to Its Direct Target Gene CD79A (mb-1) in a human Pre-B ALL Cell Line.

PAX5/TEL Causes Down Modulation of B-Lineage Specific Genes, and Enhances Migration to CXCL12 in preBI Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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