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Journal Articles

Rapid Expansion of Gene-Marked Lymphocytes in X-SCID Dogs after AMD3100+G-CSF-Based Hematopoietic Stem/Progenitor Cell Mobilization and Intravenous Injection of a Common γ-Chain Expressing Foamy Viral Vector

Frieda Chan, PhD, Olivier Humbert, PhD, Troy Torgerson, MD PhD, Nicholas Hubbard, Patricia O'Donnell, Daniel R Humphrys, B.S., Jennifer E Adair, PhD, Peter Felsburg, Grant D. Trobridge, PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 1348.

https://doi.org/10.1182/blood.V128.22.1348.1348

Published: 2016

Journal Articles

In Vivo Selection Unmasks a Dormant Pool of Repopulating Hematopoietic Clones

Jennifer E Adair, PhD, Lauren E Schefter, B.A., Daniel R Humphrys, B.S., Kevin G Haworth, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 242.

https://doi.org/10.1182/blood.V126.23.242.242

Published: 2015

Journal Articles

A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy

Jennifer E Adair, PhD, Kevin G Haworth, PhD, Guy Sauvageau, MD, PhD, Shelly Heimfeld, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 4416.

https://doi.org/10.1182/blood.V126.23.4416.4416

Published: 2015

Journal Articles

Pgk-Mediated Expression of Common Gamma Chain Is More Effective Than EF1a for Therapeutic Immune Reconstitution of X-SCID Dogs after In Vivo Gene Therapy with Foamy Virus Vector

Olivier Humbert, PhD, Christopher R Burtner, PhD, Patricia O'Donnell, Daniel R Humphrys, B.S., Nicholas Hubbard, Frieda Chan, PhD, Jennifer E Adair, PhD, Grant D. Trobridge, PhD, Troy Torgerson, MD PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD, Peter Felsburg, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 262.

https://doi.org/10.1182/blood.V126.23.262.262

Published: 2015

Journal Articles

Robust Therapeutic Expression of the Common Gamma Chain with the Human Pgk Promoter Using Foamy Virus in Vivo Gene Therapy in a Canine Model of Severe Combined Immunodeficiency

Christopher R Burtner, PhD, Olivier Humbert, PhD, Patricia O'Donnell, Nicholas Hubbard, Daniel Humphrys, Jennifer E Adair, PhD, Grant D Trobridge, PhD, Troy R Torgerson, MD PhD, Andrew M Scharenberg, MD, David Rawlings, MD, Peter J Felsburg, VMD, PhD, Hans-Peter Kiem, MD

Blood (2014) 124 (21): 4794.

https://doi.org/10.1182/blood.V124.21.4794.4794

Published: 2014

Journal Articles

Intravenous injection of a foamy virus vector to correct canine SCID-X1

Christopher R. Burtner, Brian C. Beard, Douglas R. Kennedy, Martin E. Wohlfahrt, Jennifer E. Adair, Grant D. Trobridge, Andrew M. Scharenberg, Troy R. Torgerson, David J. Rawlings, Peter J. Felsburg, Hans-Peter Kiem

Blood (2014) 123 (23): 3578–3584.

https://doi.org/10.1182/blood-2013-11-538926

Published: 2014

Includes: Supplemental data

Journal Articles

Positive selection of mC46-expressing CD4 + T cells and maintenance of virus specific immunity in a primate AIDS model

Patrick M. Younan, Patricia Polacino, John P. Kowalski, Christopher W. Peterson, Nicholas J. Maurice, Nathaniel P. Williams, On Ho, Grant D. Trobridge, Dorothee Von Laer, Martin Prlic, Brian C. Beard, Stephen DeRosa, Shiu-Lok Hu, Hans-Peter Kiem

Blood (2013) 122 (2): 179–187.

https://doi.org/10.1182/blood-2013-01-482224

Published: 2013

Includes: Supplemental data

Journal Articles

Efficient MGMTP140K-Mediated In Vivo Selection and Chemoprotection of Long-Term Repopulating Cells in Nonhuman Primates Following Reduced Intensity Conditioning.

Brian C Beard, PhD, Grant D Trobridge, PhD, Jeannine S McCune, Hans-Peter Kiem, MD

Blood (2009) 114 (22): 3572.

https://doi.org/10.1182/blood.V114.22.3572.3572

Published: 2009

Journal Articles

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients

Brian C. Beard, Reeteka Sud, Kirsten A. Keyser, Christina Ironside, Tobias Neff, Sabine Gerull, Grant D. Trobridge, Hans-Peter Kiem

Blood (2009) 113 (21): 5094–5103.

https://doi.org/10.1182/blood-2008-09-176412

Published: 2009

Includes: Supplemental data

Journal Articles

Correction of Fanconi Anemia Group A in Primary Human and Murine Hematopoietic Progenitors with a Clinical Lentiviral Vector

Jason Taylor, MD, PhD, Grant D Trobridge, PhD, Martin Wohlfahrt, Sylvia Chien, Xin Zhao, MD, Brian C Beard, PhD, Hans-Peter Kiem, MD, Pamela S. Becker, MD, PhD

Blood (2008) 112 (11): 2357.

https://doi.org/10.1182/blood.V112.11.2357.2357

Published: 2008

Journal Articles

Efficient Gene Marking with a Clinical Gammaretrovirus Vector Expressing MGMTP140K in Baboons and Macaques

Brian C Beard, PhD, Megan L Welsh, MS, Grant D Trobridge, PhD, Hans-Peter Kiem, MD

Blood (2008) 112 (11): 3535.

https://doi.org/10.1182/blood.V112.11.3535.3535

Published: 2008

Journal Articles

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

Grant D. Trobridge, Brian C. Beard, Christina Gooch, Martin Wohlfahrt, Philip Olsen, James Fletcher, Punam Malik, Hans-Peter Kiem

Blood (2008) 111 (12): 5537–5543.

https://doi.org/10.1182/blood-2007-09-115022

Published: 2008

Journal Articles

Transduction of Macaque Hematopoietic Repopulating Cells with Lenti and Foamy Retroviral Vectors with MGMT Selection Cassettes To Evaluate AIDS Gene Therapy Strategies.

Grant D. Trobridge, PhD, Brian C. Beard, Ph.D., David Dickerson, Christina Gooch, Philip Olsen, James Fletcher, Ming-Jie Li, Ph.D., Shiu-Lok Hu, Ph.D., John J. Rossi, Ph.D., Hans-Peter Kiem, M.D.

Blood (2006) 108 (11): 3273.

https://doi.org/10.1182/blood.V108.11.3273.3273

Published: 2006

Journal Articles

A Non-Human Primate Model To Study Anti-HIV Gene Therapy Strategies.

Grant D. Trobridge, PhD, Karen Beagles, PhD, Brian Beard, PhD, Ming-Jie Li, PhD, Jiing-Kuan Yee, PhD, John Rossi, PhD, Shiu-lok Hu, PhD, Hans-Peter Kiem, MD

Blood (2005) 106 (11): 3046.

https://doi.org/10.1182/blood.V106.11.3046.3046

Published: 2005

Journal Articles

Large Scale Analysis of Foamy Virus Vector Integration Sites in Human CD34+ Cells.

Grant D. Trobridge, PhD, Daniel G. Miller, MD, PhD, Michael A. Jacobs, PhD, James M. Allen, PhD, Erik Olson, Hans-Peter Kiem, MD, Rajinder Kaul, PhD, David W. Russell, MD, PhD

Blood (2004) 104 (11): 496.

https://doi.org/10.1182/blood.V104.11.496.496

Published: 2004

NARROW

Rapid Expansion of Gene-Marked Lymphocytes in X-SCID Dogs after AMD3100+G-CSF-Based Hematopoietic Stem/Progenitor Cell Mobilization and Intravenous Injection of a Common γ-Chain Expressing Foamy Viral Vector

In Vivo Selection Unmasks a Dormant Pool of Repopulating Hematopoietic Clones

A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy

Pgk-Mediated Expression of Common Gamma Chain Is More Effective Than EF1a for Therapeutic Immune Reconstitution of X-SCID Dogs after In Vivo Gene Therapy with Foamy Virus Vector

Robust Therapeutic Expression of the Common Gamma Chain with the Human Pgk Promoter Using Foamy Virus in Vivo Gene Therapy in a Canine Model of Severe Combined Immunodeficiency

Intravenous injection of a foamy virus vector to correct canine SCID-X1

Positive selection of mC46-expressing CD4 + T cells and maintenance of virus specific immunity in a primate AIDS model

Efficient MGMTP140K-Mediated In Vivo Selection and Chemoprotection of Long-Term Repopulating Cells in Nonhuman Primates Following Reduced Intensity Conditioning.

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients

Correction of Fanconi Anemia Group A in Primary Human and Murine Hematopoietic Progenitors with a Clinical Lentiviral Vector

Efficient Gene Marking with a Clinical Gammaretrovirus Vector Expressing MGMTP140K in Baboons and Macaques

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

Transduction of Macaque Hematopoietic Repopulating Cells with Lenti and Foamy Retroviral Vectors with MGMT Selection Cassettes To Evaluate AIDS Gene Therapy Strategies.

A Non-Human Primate Model To Study Anti-HIV Gene Therapy Strategies.

Large Scale Analysis of Foamy Virus Vector Integration Sites in Human CD34+ Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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