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Gajalakshmi Ramanathan
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Journal Articles

Wild-Type Calreticulin Downmodulates MPL and Impacts HSC Self-Renewal

Kiana K. Guillermo, Stefan Brooks, Lucas Wadley, Jianhong C Heidmann, Helen Huang, Jane Chen, Aanya Amin, Anaya Qamar, Brianna Hoover, Gajalakshmi Ramanathan, Angela G. Fleischman
Journal: Blood
Blood (2023) 142 (Supplement 1): 1782.
https://doi.org/10.1182/blood-2023-189705
Published: 2023
Journal Articles

Signaling Pathway Gene Set Enrichment Analysis in Whole Exome Sequencing Data from Discordant Identical Twins Unveils Relevant Pathways As a Clue to Understand Somatic Mutation Acquisition and Clonal Evolution in Myeloproliferative Neoplasms

Eduard Mas Marin, Sabrina Mir, Eli M Soyfer, Jane H Chen, Jianhong C Heidmann, Simran Bhardwaj, Gajalakshmi Ramanathan, Angela G. Fleischman
Journal: Blood
Blood (2023) 142 (Supplement 1): 4525.
https://doi.org/10.1182/blood-2023-189085
Published: 2023
Journal Articles

Mitigating Oxidative Stress Promotes Quiescence of Hematopoietic Stem Cells from Concurrent TLR4 Activation and IL-10R Blockade Mediated Inflammation

Sultan A Alsuhaibani, Jeanette Y Sullivan, Tiffany Trieu, Helen Huang, Jianhong C Heidmann, Jared E Agagas, Kevin Arango, Dennis Jing, Gajalakshmi Ramanathan, Angela G. Fleischman
Journal: Blood
Blood (2023) 142 (Supplement 1): 1302.
https://doi.org/10.1182/blood-2023-185279
Published: 2023
Journal Articles

Expansion and Blunted Inflammatory Responses of Jak2 V617F Cells in the Setting of Electronic Cigarette Aerosol Inhalation

Jeanette Y Sullivan, Jane H Chen, Helen Huang, Kevin Arango, Dennis Jing, Jared E Agagas, Gajalakshmi Ramanathan, Bishop Bliss, David Herman, Michael Kleinman, Angela G. Fleischman
Journal: Blood
Blood (2023) 142 (Supplement 1): 5600.
https://doi.org/10.1182/blood-2023-188198
Published: 2023
Journal Articles

IL-10R Inhibition Selects for Jak2V617F Hematopoiesis By Augmenting Inflammation Induced Exhaustion of Wild-Type but Not Jak2V617F Hematopoietic Stem Cells

Angela Fleischman, Hew Yeng Lai, Nitya Mehrota-Venkat, Tiffany Trieu, Tiffany Han, Gajalakshmi Ramanathan, Brianna Hoover
Journal: Blood
Blood (2021) 138 (Supplement 1): 3595.
https://doi.org/10.1182/blood-2021-154107
Published: 2021
Journal Articles

Cigarette Smoke and E-Cigarette Aerosols Lead to Clonal Expansion of Tet2 -/- and Dnmt3a R878H Cells In Vivo

Gajalakshmi Ramanathan, Rebecca Johnson, Jane Huishien Chen, Aaron Jia-En Huang, Bishop Bliss, Michael T. Kleinman, Angela Fleischman
Journal: Blood
Blood (2021) 138 (Supplement 1): 2167.
https://doi.org/10.1182/blood-2021-151322
Published: 2021
Journal Articles

Single-Cell RNA-Seq to Assess Differential Responses to Tnfα in Human Hematopoietic Stem and Progenitor Cells in Myeloproliferative Neoplasm

Brianna Craver, MS, Quy Nguyen, Gajalakshmi Ramanathan, PhD, Angela G. Fleischman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2518.
https://doi.org/10.1182/blood-2019-123480
Published: 2019
Journal Articles

JAK2V617F Hematopoietic Stem and Progenitors Are More Resistant to Chronic Blockage of IL-10 Signaling in a Murine Model of Myeloproliferative Neoplasms

Hew Yeng Lai, PhD, Tiffany Trieu, Tiffany Han, Stefan Brooks, Brianna Craver, MS, Gajalakshmi Ramanathan, PhD, Angela G. Fleischman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4206.
https://doi.org/10.1182/blood-2019-131166
Published: 2019
Journal Articles

N-Acetylcysteine As a Therapeutic for JAK2V617F Myeloproliferative Neoplasms

Brianna Craver, MS, Gajalakshmi Ramanathan, PhD, Laura Mendez Luque, Summer Hoang, Kenza Elalaoui, MD, Stefan Brooks, Hew Yeng Lai, Angela Fleischman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1786.
https://doi.org/10.1182/blood-2018-99-117395
Published: 2018