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Journal Articles

A STAT3 Degrader Demonstrates Pre-Clinical Efficacy in Venetoclax Resistant Acute Myeloid Leukemia

Samarpana Chakraborty, Claudia Morganti, Joyoti Dey, Hui Zhang, Srinivas Aluri, Nadege Gitego, Kith Pradhan, Bianca Rivera, Yogesh Chutake, Anna Skwarska, Ioannis Mantzaris, Mendel Goldfinger, Eric J Feldman, Gaurav S Choudhary, Stefan Hubner, Yihua Qiu, Brandon D. Brown, Amit Verma, Evripidis Gavathiotis, Marina Y. Konopleva, Steven M. Kornblau, Jared Gollob, Keisuke Ito, Aditi Shastri
Journal: Blood
Blood (2023) 142 (Supplement 1): 2787.
https://doi.org/10.1182/blood-2023-186947
Published: 2023
Journal Articles

Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS: Assessment of Leukemia Stem Cell Eradication By High-Resolution MRD Assay

Ioannis Mantzaris, Mendel Goldfinger, David Levitz, Kateryna Fedorov, Karen Fehn, Nicole Chambers, Anne Munoz, Aradhika Dhawan, Joel Victor, Nishi Shah, Aditi Shastri, Noah Kornblum, R. Alejandro Sica, Kira Gritsman, Dennis Cooper, Mimi Kim, Evripidis Gavathiotis, Marina Konopleva, Amit Verma, Eric J. Feldman, Ulrich G. Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 3360–3361.
https://doi.org/10.1182/blood-2022-167849
Published: 2022
Journal Articles

Direct Pharmacological Inhibition of the Transcription Factor PU.1 in Acute Myeloid Leukemia

Ileana Antony-Debre, PhD, Ananya Paul, Joana Leite, Kelly Mitchell, Hye Mi Kim, Luis A. Carvajal, PhD, Tihomira Tidorova, Samuel Taylor, Kenneth Huang, Arvind Kumar, Abdelbasset A Farahat, Boris Bartholdy, PhD, Swathi-Rao Narayanagari, M.S, Jiahao Chen, Alberto Ambesi-Impiombato, Adolfo A. Ferrando, MD PhD, Ioannis Mantzaris, MD, Evripidis Gavathiotis, CPA, PhD BSc, Amit Verma, MD, Britta Will, PhD, David W Boykin, W David Wilson, Gregory MK Poon, Ulrich G. Steidl, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 858.
https://doi.org/10.1182/blood.V130.Suppl_1.858.858
Published: 2017
Journal Articles

Dissecting the Activation Pathway of Pro-Apoptotic BAX: Mechanistic Insights and Pharmacologic Opportunities.

Evripidis Gavathiotis, PhD, Marguerite Davis, Denis Reyna Ruiz, Gregory H. Bird, PhD, Loren D. Walensky, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 768.
https://doi.org/10.1182/blood.V114.22.768.768
Published: 2009
Journal Articles

Structural Analysis of a BAX-BIM SAHB Complex Reveals a Novel BH3 Interaction Site on BAX for Therapeutic Activation of Apoptosis

Evripidis Gavathiotis, Ph.D., Motoshi Suzuki, Ph.D., Marguerite L. Davis, Kenneth Pitter, Gregory H. Bird, PhD, Samuel G. Katz, MD, PhD, Ho-Chou Tu, Hyungjin Kim, Emily Cheng, M.D., Ph.D., Nico Tjandra, Ph.D., Loren D. Walensky, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 300.
https://doi.org/10.1182/blood.V112.11.300.300
Published: 2008