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Eugene Hwang
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Journal Articles

Co-Targeting BET Bromodomain Proteins and Aberrant Signaling in AML

Benjamin J. Huang, MD, Xinyue Wang, BA, Max Harris, BA, Anica Wandler, PhD, Eugene Hwang, BA, Michael R. Burgess, MD PhD, Qing Li, MD PhD, Paul Severson, PhD, Ben Powell, PhD, Edward A. Kolb, MD, Soheil Meshinchi, MDPhD, Barry S Taylor, PhD, Gideon Bollag, PhD, Kevin M. Shannon, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-142921
Published: 2020
Journal Articles

Response and Resistance to Bromodomain Inhibition in AML Driven By Hyperactive Ras Signaling

Benjamin Huang, MD, Eugene Hwang, Anica M. Wandler, PhD, Ben Powell, PhD, Gideon Bollag, PhD, Kevin Shannon, MD
Journal: Blood
Blood (2016) 128 (22): 1654.
https://doi.org/10.1182/blood.V128.22.1654.1654
Published: 2016
Journal Articles

Preclinical efficacy of MEK inhibition in Nras -mutant AML

Michael R. Burgess, Eugene Hwang, Ari J. Firestone, Tannie Huang, Jin Xu, Johannes Zuber, Natacha Bohin, Tiffany Wen, Scott C. Kogan, Kevin M. Haigis, Deepak Sampath, Scott Lowe, Kevin Shannon, Qing Li
Journal: Blood
Blood (2014) 124 (26): 3947–3955.
https://doi.org/10.1182/blood-2014-05-574582
Published: 2014
Includes: Supplemental data
Journal Articles

Loss of Wild-Type Kras is Associated with Enhanced Fitness and Increased Mitogen-Activated Protein Kinase Pathway Addiction in K-Ras G12D Acute Myeloid Leukemia

Michael R. Burgess, MD PhD, Eugene Hwang, BA, Anica M. Wandler, PhD, Saurabh Asthana, PhD, Elizabeth M. Davis, BS, Michelle M. Le Beau, PhD, Barry Taylor, PhD, Kevin Shannon, MD
Journal: Blood
Blood (2014) 124 (21): 907.
https://doi.org/10.1182/blood.V124.21.907.907
Published: 2014
Journal Articles

Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia

Michael R. Burgess, MD PhD, Eugene Hwang, BA, Ari J Firestone, PhD, Tannie Huang, MD, Jin Xu, PhD, Johannes Zuber, MD, Natacha Bohin, BS, Tiffany Wen, BS, Scott C. Kogan, MD, Kevin M. Haigis, PhD, Scott W. Lowe, PhD, Kevin Shannon, MD, Qing Li, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3753.
https://doi.org/10.1182/blood.V124.21.3753.3753
Published: 2014
Journal Articles

Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras

Brief Report
Jin Xu, Christian Hedberg, Frank J. Dekker, Qing Li, Kevin M. Haigis, Eugene Hwang, Herbert Waldmann, Kevin Shannon
Journal: Blood
Blood (2012) 119 (4): 1032–1035.
https://doi.org/10.1182/blood-2011-06-358960
Published: 2012
Includes: Supplemental data
Journal Articles

Heterozygous Germ Line Deletion of a 2Mb Interval in Mice That Models Loss of 7q22 in Human Myeloid Malignancies Results in Defective Hematopoietic Stem Cell Function Reminiscent of Premature Aging

Jasmine C. Wong, PhD, Kelley Weinfurtner, BA, Yan Zhang, Ph.D., Pilar Alzamora, Eugene Hwang, BA, Scott C. Kogan, MD, Kevin M. Shannon, MD
Journal: Blood
Blood (2011) 118 (21): 2340.
https://doi.org/10.1182/blood.V118.21.2340.2340
Published: 2011