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Journal Articles

Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product

Emily J Pomeroy, Andrew V Anzalone, Christopher J Podracky, Noah B Bloch, Reyna Chang, Arika A Dwivedi, Kanut Laoharawee, Alan J Wilhelm, David P Waterman, Justin G Tedeschi, Upasana Sunil Arvindam, Elizabeth R Macari, Jennifer L Gori, Jeremy S Duffield

Blood (2023) 142 (Supplement 1): 4803.

https://doi.org/10.1182/blood-2023-181869

Published: 2023

Journal Articles

Lovo-cel (bb1111) Gene Therapy for Sickle Cell Disease: Updated Clinical Results and Investigations into Two Cases of Anemia from Group C of the Phase 1/2 HGB-206 Study

Mark C. Walters, Alexis A. Thompson, Janet L. Kwiatkowski, Suhag Parikh, Markus Y. Mapara, Stacey Rifkin-Zenenberg, Banu Aygun, Kimberly A. Kasow, Alex Miller, Lixin Zhang, Anjulika Chawla, Elizabeth R. Macari, Francis J. Pierciey, Jr., John F. Tisdale, Julie Kanter

Blood (2022) 140 (Supplement 1): 26–28.

https://doi.org/10.1182/blood-2022-162288

Published: 2022

Journal Articles

Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling

Elizabeth R Macari, PhD, Alison M Taylor, PhD, David Raiser, PhD, Kavitha Siva, PhD, Katherine McGrath, Jessica M Humphries, Johan Flygare, MDPhD, Benjamin L. Ebert, MDPhD, Leonard I. Zon, MD

Blood (2016) 128 (22): 332.

https://doi.org/10.1182/blood.V128.22.332.332

Published: 2016

Journal Articles

Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency in in Vitro and In Vivo Diamond Blackfan Anemia Models

Elizabeth R Macari, PhD, Alison Taylor, PhD, David Raiser, PhD, Kavitha Siva, PhD, Katherine McGrath, Jessica M Humphries, Johan Flygare, MD PhD, Benjamin L Ebert, MD PhD, Leonard I. Zon, MD

Blood (2015) 126 (23): 672.

https://doi.org/10.1182/blood.V126.23.672.672

Published: 2015

Journal Articles

Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells

Sergei Doulatov, PhD, Linda T Vo, Elizabeth R Macari, PhD, Stephanie S Chou, Manav Gupta, Michelle Godfrey, Katherine McGrath, Thorsten M Schlaeger, PhD, Leonard I. Zon, MD, George Q. Daley, MD PhD

Blood (2014) 124 (21): 359.

https://doi.org/10.1182/blood.V124.21.359.359

Published: 2014

Journal Articles

Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families

Lisa Mirabello, Elizabeth R. Macari, Lea Jessop, Steven R. Ellis, Timothy Myers, Neelam Giri, Alison M. Taylor, Katherine E. McGrath, Jessica M. Humphries, Bari J. Ballew, Meredith Yeager, Joseph F. Boland, Ji He, Belynda D. Hicks, Laurie Burdett, Blanche P. Alter, Leonard Zon, Sharon A. Savage

Blood (2014) 124 (1): 24–32.

https://doi.org/10.1182/blood-2013-11-540278

Published: 2014

Includes: Supplemental data

Journal Articles

Functional Consequences Of RPS29 Germline Mutations In Diamond-Blackfan Anemia

Lisa Mirabello, PhD, Elizabeth R Macari, PhD, Lea Jessop, PhD, Timothy Myers, PhD, Neelam Giri, MD, Alison M. Taylor, PhD, Katherine E. McGrath, Jessica M. Humphries, Bari J Ballew, PhD, Meredith Yeager, PhD, Joseph F Boland, Ji He, Belynda D Hicks, Laurie Burdett, PhD, Blanche P Alter, MD, MPH, Leonard I. Zon, MD, Sharon A Savage, MD

Blood (2013) 122 (21): 2465.

https://doi.org/10.1182/blood.V122.21.2465.2465

Published: 2013

Journal Articles

Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells

Elizabeth R. Macari, Emily K. Schaeffer, Rachel J. West, Christopher H. Lowrey

Blood (2013) 121 (5): 830–839.

https://doi.org/10.1182/blood-2012-07-443986

Published: 2013

Journal Articles

Simvastatin and tBHQ Act Synergistically to Increase γ-Globin Gene Expression Through the Transcription Factors KLF2 and NRF2

Elizabeth R Macari, BS, Christopher H. Lowrey, MD

Blood (2011) 118 (21): 2149.

https://doi.org/10.1182/blood.V118.21.2149.2149

Published: 2011

Journal Articles

Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway

Elizabeth R. Macari, Christopher H. Lowrey

Blood (2011) 117 (22): 5987–5997.

https://doi.org/10.1182/blood-2010-10-314096

Published: 2011

Journal Articles

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Elizabeth R. Macari, BS, Rachel J. West, PhD, Christopher H. Lowrey, MD

Blood (2010) 116 (21): 2074.

https://doi.org/10.1182/blood.V116.21.2074.2074

Published: 2010

Journal Articles

Dual-Specificity Phosphatases (DUSPs) Are Potential Targets for Pharmacologic Induction of Fetal Hemoglobin

Cynthia K Hahn, BA, Rachel J West, PhD, Elizabeth R Macari, BS, Emily K Schaeffer, BSc, Christopher H. Lowrey, MD

Blood (2010) 116 (21): 2075.

https://doi.org/10.1182/blood.V116.21.2075.2075

Published: 2010

NARROW

Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product

Lovo-cel (bb1111) Gene Therapy for Sickle Cell Disease: Updated Clinical Results and Investigations into Two Cases of Anemia from Group C of the Phase 1/2 HGB-206 Study

Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling

Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency in in Vitro and In Vivo Diamond Blackfan Anemia Models

Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells

Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families

Functional Consequences Of RPS29 Germline Mutations In Diamond-Blackfan Anemia

Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells

Simvastatin and tBHQ Act Synergistically to Increase γ-Globin Gene Expression Through the Transcription Factors KLF2 and NRF2

Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Dual-Specificity Phosphatases (DUSPs) Are Potential Targets for Pharmacologic Induction of Fetal Hemoglobin

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American Society of Hematology

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ASH Publications

American Society of Hematology

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