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Jennifer L Gori
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Journal Articles

Prime Editing Enables Precise and Efficient Single Amino Acid Substitutions to Shield CD34+ Hematopoietic Stem Cells from Anti-CD117 Antibody-Based Conditioning

Jack M Heath, Justin G Tedeschi, Upasana Sunil Arvindam, Simran Padhye, Kanut Laoharawee, Allen C Ng, David P Waterman, Matthew S Roy, Seth C Alexander, Sarah Trusiak, Christopher Divsalar, Azhaar Alturkistani, Barrett J Nehilla, Mallik R Putta, Katya Kosheleva, Hetal K Patel, Rowshon Alam, Stefanie Urlinger, Jeremy S Duffield, Jennifer L Gori
Journal: Blood
Blood (2024) 144 (Supplement 1): 514.
https://doi.org/10.1182/blood-2024-203602
Published: 2024
Journal Articles

Prime Editing Efficiently and Precisely Corrects Causative Mutation in Chronic Granulomatous Disease, Restoring Myeloid Function: Toward Development of a Prime Edited Autologous Hematopoietic Stem Cell Therapy

Jack M Heath, Jacob Stuart Orenstein, Justin G Tedeschi, Allen Ng, Maria D Collier, Julia Kushakji, Alan J Wilhelm, Andrew Taylor, David P Waterman, Suk See De Ravin, Harry L Malech, Andrew V Anzalone, Jeremy S Duffield, Jennifer L Gori
Journal: Blood
Blood (2023) 142 (Supplement 1): 7129.
https://doi.org/10.1182/blood-2023-186365
Published: 2023
Journal Articles

Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product

Emily J Pomeroy, Andrew V Anzalone, Christopher J Podracky, Noah B Bloch, Reyna Chang, Arika A Dwivedi, Kanut Laoharawee, Alan J Wilhelm, David P Waterman, Justin G Tedeschi, Upasana Sunil Arvindam, Elizabeth R Macari, Jennifer L Gori, Jeremy S Duffield
Journal: Blood
Blood (2023) 142 (Supplement 1): 4803.
https://doi.org/10.1182/blood-2023-181869
Published: 2023
Journal Articles

Small Molecule Regulated Cytokine Expression Enables Potent and Durable Responses to Engineered T-Cell Therapy

Vipin Suri, PhD MBA, Jennifer L Gori, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2045.
https://doi.org/10.1182/blood-2018-99-111922
Published: 2018
Journal Articles

Expanding CRISPR Genome Editing Strategies in Hematopoietic Stem and Progenitor Cells for the Treatment of Hematologic Diseases

Edouard deDreuzy, PhD, Aditi Chalishazar, MS, Jack Heath, Carrie M Margulies, PhD, John Labella, Ramya Viswanathan, Katherine Loveluck, KaiHsin Chang, PhD, Hariharan Jayaram, PhD, John A Zuris, PhD, Vic E Myer, PhD, Charlie Albright, PhD, Cecilia Cotta-Ramusino, PhD, Jennifer L Gori, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4619.
https://doi.org/10.1182/blood.V130.Suppl_1.4619.4619
Published: 2017
Journal Articles

Precise and Efficient Crispr/Cas9 Mediated Gene Editing in Long-Term Engrafting Human Hematopoietic Stem/Progenitor Cells

Jack M Heath, BS, Aditi Chalishazar, MS, Christina S Lee, BA, William Selleck, BS, Cecilia Cotta-Ramusino, PhD, David Bumcrot, PhD, Jennifer L Gori, PhD
Journal: Blood
Blood (2016) 128 (22): 2312.
https://doi.org/10.1182/blood.V128.22.2312.2312
Published: 2016
Journal Articles

Vascular Niche-Derived Angiocrine Factors Specify and Maintain Hematopoietic Stem Cells

Shahin Rafii, MD, Jason M. Butler, PhD, Ginsberg Michael, PhD, Jennifer L Gori, PhD, Hans-Peter Kiem, MD, Scandura Jospeh, MD PhD
Journal: Blood
Blood (2015) 126 (23): SCI-25.
https://doi.org/10.1182/blood.V126.23.SCI-25.SCI-25
Published: 2015
Journal Articles

Effective Expansion and Engraftment Of Nonhuman Primate CD34 + Hematopoietic Stem Cells After Co-Culture With The Small Molecule UM171

Jennifer L Gori, PhD, Korashon L Watts, PhD, Devikha Chandrasekaran, MS, Guy Sauvageau, MD, PhD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2013) 122 (21): 1656.
https://doi.org/10.1182/blood.V122.21.1656.1656
Published: 2013
Journal Articles

In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells

Jennifer L Gori, PhD, Jason M Butler, PhD, Devikha Chandrasekaran, MS, Brian C Beard, PhD, Daniel J Nolan, PhD, Michael Ginsberg, PhD, Jennifer E Adair, PhD, Shahin Rafii, MD, Hans-Peter Kiem, MD
Journal: Blood
Blood (2013) 122 (21): 466.
https://doi.org/10.1182/blood.V122.21.466.466
Published: 2013
Journal Articles

Efficient generation, purification, and expansion of CD34 + hematopoietic progenitor cells from nonhuman primate–induced pluripotent stem cells

e-blood
Jennifer L. Gori, Devikha Chandrasekaran, John P. Kowalski, Jennifer E. Adair, Brian C. Beard, Sunita L. D'Souza, Hans-Peter Kiem
Journal: Blood
Blood (2012) 120 (13): e35–e44.
https://doi.org/10.1182/blood-2012-05-433797
Published: 2012
Includes: Supplemental data