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Edward J. Kerschen
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Journal Articles

Coagulation Factor V Mediates Inhibition of Tissue Factor Signaling By Activated Protein C

Hartmut Weiler, Hai-Po Liang, PhD, Edward J Kerschen, PhD, Alireza Rezaie, PhD, Jose A. Fernandez, MD PhD, Rodney M. Camire, PhD, Wolfram Ruf, MD, John H. Griffin, PhD, Raffaele Toso, PhD
Journal: Blood
Blood (2015) 126 (23): 216.
https://doi.org/10.1182/blood.V126.23.216.216
Published: 2015
Journal Articles

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice

Hai Po H. Liang, Edward J. Kerschen, Sreemanti Basu, Irene Hernandez, Mark Zogg, Shuang Jia, Martin J. Hessner, Raffaella Toso, Alireza R. Rezaie, José A. Fernández, Rodney M. Camire, Wolfram Ruf, John H. Griffin, Hartmut Weiler
Journal: Blood
Blood (2015) 126 (21): 2415–2423.
https://doi.org/10.1182/blood-2015-05-644401
Published: 2015
Includes: Supplemental data
Journal Articles

EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice

Hai Po H. Liang, Edward J. Kerschen, Irene Hernandez, Sreemanti Basu, Mark Zogg, Fady Botros, Shuang Jia, Martin J. Hessner, John H. Griffin, Wolfram Ruf, Hartmut Weiler
Journal: Blood
Blood (2015) 125 (18): 2845–2854.
https://doi.org/10.1182/blood-2014-11-610717
Published: 2015
Includes: Supplemental data
Journal Articles

Factor V Inhibits PAR2-Mediated Lethal Inflammation

Edward J Kerschen, PhD, Hai-Po Helena Liang, Jose A. Fernandez, MD, PhD, Raffaella Toso, PhD, Wolfram Ruf, MD, Rodney M. Camire, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD
Journal: Blood
Blood (2012) 120 (21): 3360.
https://doi.org/10.1182/blood.V120.21.3360.3360
Published: 2012
Journal Articles

Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant

Laurent O. Mosnier, Antonella Zampolli, Edward J. Kerschen, Reto A. Schuepbach, Yajnavalka Banerjee, José A. Fernández, Xia V. Yang, Matthias Riewald, Hartmut Weiler, Zaverio M. Ruggeri, John H. Griffin
Journal: Blood
Blood (2009) 113 (23): 5970–5978.
https://doi.org/10.1182/blood-2008-10-183327
Published: 2009
Includes: Supplemental data
Journal Articles

Caveolin-1–dependent apoptosis induced by fibrin degradation products

Yi-He Guo, Irene Hernandez, Berend Isermann, Tae-bong Kang, Leonid Medved, Rashmi Sood, Edward J. Kerschen, Trudy Holyst, Michael W. Mosesson, Hartmut Weiler
Journal: Blood
Blood (2009) 113 (18): 4431–4439.
https://doi.org/10.1182/blood-2008-07-169433
Published: 2009
Journal Articles

Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5

Ryan D. Schulteis, Haiyan Chu, Xuezhi Dai, Yuhong Chen, Brandon Edwards, Dipica Haribhai, Calvin B. Williams, Subramaniam Malarkannan, Martin J. Hessner, Sanja Glisic-Milosavljevic, Srikanta Jana, Edward J. Kerschen, Soumitra Ghosh, Demin Wang, Anne E. Kwitek, Ake Lernmark, Jack Gorski, Hartmut Weiler
Journal: Blood
Blood (2008) 112 (13): 4905–4914.
https://doi.org/10.1182/blood-2008-03-146555
Published: 2008
Includes: Supplemental data
Journal Articles

Mechanisms for Mortality Reduction by Activated Protein C in Severe Sepsis.

Edward J. Kerschen, PhD, Brian C. Cooley, PhD, Francis J. Castellino, PhD, Shaun R. Coughlin, MD, PhD, Jose A. Fernandez, MD, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD
Journal: Blood
Blood (2006) 108 (11): 1.
https://doi.org/10.1182/blood.V108.11.1.1
Published: 2006
Journal Articles

Protective Effect of Activated Protein C in Murine Endotoxemia: Mechanism of Action.

Edward J. Kerschen, PhD, Brian C. Cooley, MD, Francis J. Castellino, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD
Journal: Blood
Blood (2005) 106 (11): 26.
https://doi.org/10.1182/blood.V106.11.26.26
Published: 2005