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Dorian H LaTocha
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Journal Articles

Dasatinib Shows Therapeutic Potential in the Murine Xenograft Model for TCF3 rearranged Acute Lymphoblastic Leukemia

Kyle Lenz, Sarah Thompson, Natalya A. Goloviznina, B.S., Jianya Huan, PhD, Dorian H LaTocha, BS, Brian J. Druker, Jeffrey W. Tyner, Peter Kurre, MD, Bill H Chang, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3718.
https://doi.org/10.1182/blood.V124.21.3718.3718
Published: 2014
Journal Articles

BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein

Anupriya Agarwal, Ryan J. Mackenzie, Arnaud Besson, Sophia Jeng, Alyssa Carey, Dorian H. LaTocha, Angela G. Fleischman, Nicolas Duquesnes, Christopher A. Eide, Kavin B. Vasudevan, Marc M. Loriaux, Eduardo Firpo, Jorge E. Cortes, Shannon McWeeney, Thomas O’Hare, James M. Roberts, Brian J. Druker, Michael W. Deininger
Journal: Blood
Blood (2014) 124 (22): 3260–3273.
https://doi.org/10.1182/blood-2013-04-497040
Published: 2014
Includes: Supplemental data
Journal Articles

Exaggerated Response To Toll-Like Receptor Agonist Contributes To Excessive TNF Production In Myeloproliferative Neoplasm

Angela G. Fleischman, MD, PhD, Samuel B Luty, BS, Michael R Garbati, PhD, J Blair Edmiston, BS, Lacey R Royer, Dorian H LaTocha, BS, Grover C. Bagby, M.D., Brian J. Druker
Journal: Blood
Blood (2013) 122 (21): 4097.
https://doi.org/10.1182/blood.V122.21.4097.4097
Published: 2013
Journal Articles

TNFα facilitates clonal expansion of JAK2 V617F positive cells in myeloproliferative neoplasms

Angela G. Fleischman, Karl J. Aichberger, Samuel B. Luty, Thomas G. Bumm, Curtis L. Petersen, Shirin Doratotaj, Kavin B. Vasudevan, Dorian H. LaTocha, Fei Yang, Richard D. Press, Marc M. Loriaux, Heike L. Pahl, Richard T. Silver, Anupriya Agarwal, Thomas O'Hare, Brian J. Druker, Grover C. Bagby, Michael W. Deininger
Journal: Blood
Blood (2011) 118 (24): 6392–6398.
https://doi.org/10.1182/blood-2011-04-348144
Published: 2011
Includes: Supplemental data
Journal Articles

Cryptic Intracellular Retention of ABL Tyrosine Kinase Inhibitors within CML Cells Mediates Apoptosis Commitment Following Acute Drug Exposure,

Thomas O'Hare, Christopher A. Eide, Lauren T. Adrian, Anupriya Agarwal, PhD, Matthew S. Zabriskie, Ryan MacKenzie, BS, Dorian H. LaTocha, BS, Huihong You, PhD, Jenny Luo, BS, Steven M. Riddle, PhD, Bryan Marks, PhD, Dennis R. Koop, PhD, John Apgar, PhD, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2011) 118 (21): 3504.
https://doi.org/10.1182/blood.V118.21.3504.3504
Published: 2011
Journal Articles

p27 Is Mislocalized to the Cytoplasm by BCR-ABL In a Kinase-Independent Manner and Contributes to Leukemogenesis

Anupriya Agarwal, PhD, Ryan J Meckenzie, Thomas O'Hare, PhD, Kavin B Vasudevan, Dorian H LaTocha, Marc M Loriaux, MD, PhD, Eduardo Firpo, James M Roberts, Brian J Druker, MD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 512.
https://doi.org/10.1182/blood.V116.21.512.512
Published: 2010