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Journal Articles

Targeting Pim Kinase Activity with the Novel Small Molecule Inhibitor SGI-1776 Significantly Augments the Efficacy of Cytarabine In Models of Acute Myeloid Leukemia

Kevin R Kelly, MD, Kelli Oberheu, B.S., Ernest Medina, B.S., Claudia M Espitia, MS, Devalingam Mahalingam, MD, PhD, Pietro Taverna, PhD, Gavin S. Choy, PharmD, MBA, Steffan T Nawrocki, PhD, Francis J. Giles, MB, MD, FRCPI, FRCPath, Jennifer S Carew, PhD

Blood (2010) 116 (21): 3253.

https://doi.org/10.1182/blood.V116.21.3253.3253

Published: 2010

Journal Articles

Disrupting NEDD8-Mediated Protein Turnover with MLN4924 Significantly Augments the Efficacy of Cytarabine

Steffan T Nawrocki, PhD, Kevin R Kelly, MD, Kelli Oberheu, B.S., Devalingam Mahalingam, MD, PhD, Peter G Smith, PhD, Jennifer S Carew, PhD

Blood (2010) 116 (21): 3255.

https://doi.org/10.1182/blood.V116.21.3255.3255

Published: 2010

Journal Articles

A New Rotary Powered Device for Bone Marrow Aspiration and Biopsy Yields Superior Specimens with Less Pain: Results of a Randomized Clinical Study

Ronan Swords, MD, MRCPI, FRCPath, Javier Anguita, MD, Russell A. Higgins, MD, Andrea Yunes, MD, Michael Naski, MD, PhD, Swaminathan Padmanabhan, MD, Kevin R Kelly, MD, Devalingam Mahalingam, MD, PhD, Thomas Philbeck, PhD, Larry Miller, MD, Francis J. Giles, MB, MD, FRCPI, FRCPath, Marsha Kinney, MD, Andrew Brenner, MD

Blood (2010) 116 (21): 1529.

https://doi.org/10.1182/blood.V116.21.1529.1529

Published: 2010

Journal Articles

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia

Ronan T. Swords, Kevin R. Kelly, Peter G. Smith, James J. Garnsey, Devalingam Mahalingam, Ernest Medina, Kelli Oberheu, Swaminathan Padmanabhan, Michael O'Dwyer, Steffan T. Nawrocki, Francis J. Giles, Jennifer S. Carew

Blood (2010) 115 (18): 3796–3800.

https://doi.org/10.1182/blood-2009-11-254862

Published: 2010

Includes: Supplemental data

Journal Articles

Use of a New Rotary Powered Device for Bone Marrow Aspiration and Biopsy Yields Excellent Specimens Quickly and Efficiently.

Ronan T. Swords, MD, MRCPI, FRCPath, Kevin R. Kelly, MD, MRCPI, FRCPath, Devalingam Mahalingam, MD, PhD, Stephen C. Cohen, MD, Larry J. Miller, MD, Thomas E. Philbeck, Jr., PhD, MBA, Sander O. Hacker, VMD, DACLAM, Cathy J. Spadaccini, MD, Andrew Brenner, MD, PhD, Francis J. Giles, MB, MD, FRCPI, FRCPath

Blood (2009) 114 (22): 4544.

https://doi.org/10.1182/blood.V114.22.4544.4544

Published: 2009

Journal Articles

MLN4924, A Novel First in Class Small Molecule Inhibitor of the Nedd8 Activating Enzyme (NAE), Has Potent Activity in Preclinical Models of Acute Myeloid Leukemia.

Ronan T. Swords, M.D., Kevin R. Kelly, MD, Peter G. Smith, PhD, James J. Gansey, Devalingam Mahalingam, M.D., Swaminathan Padmanabhan, MD, MBBS, Michael C. O'Dwyer, MD, FRCPI, FRCPath, Steffan T. Nawrocki, PhD, Francis J. Giles, MD, Jennifer S. Carew, Ph.D.

Blood (2009) 114 (22): 1021.

https://doi.org/10.1182/blood.V114.22.1021.1021

Published: 2009

Journal Articles

The Novel Orally Active Aurora A Kinase Inhibitor MLN8237 Is Highly Active in Preclinical Models of Acute Myeloid Leukemia and Significantly Increases the Efficacy of Cytarabine.

Kevin R. Kelly, MD, Ronan T. Swords, M.D., Devalingam Mahalingam, M.D., Steffan T. Nawrocki, PhD, Ernest Medina, B.S., Sabrina Smith, Swaminathan Padmanabhan, MD, MBBS, Jeffrey Ecsedy, Mary R Cahill, FRCPI, FRCPath, Francis J. Giles, MB, MD, FRCPI, FRCPath, Jennifer S. Carew, Ph.D.

Blood (2009) 114 (22): 2087.

https://doi.org/10.1182/blood.V114.22.2087.2087

Published: 2009

NARROW

Targeting Pim Kinase Activity with the Novel Small Molecule Inhibitor SGI-1776 Significantly Augments the Efficacy of Cytarabine In Models of Acute Myeloid Leukemia

Disrupting NEDD8-Mediated Protein Turnover with MLN4924 Significantly Augments the Efficacy of Cytarabine

A New Rotary Powered Device for Bone Marrow Aspiration and Biopsy Yields Superior Specimens with Less Pain: Results of a Randomized Clinical Study

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia

Use of a New Rotary Powered Device for Bone Marrow Aspiration and Biopsy Yields Excellent Specimens Quickly and Efficiently.

MLN4924, A Novel First in Class Small Molecule Inhibitor of the Nedd8 Activating Enzyme (NAE), Has Potent Activity in Preclinical Models of Acute Myeloid Leukemia.

The Novel Orally Active Aurora A Kinase Inhibitor MLN8237 Is Highly Active in Preclinical Models of Acute Myeloid Leukemia and Significantly Increases the Efficacy of Cytarabine.

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ASH Publications

American Society of Hematology

Targeting Pim Kinase Activity with the Novel Small Molecule Inhibitor SGI-1776 Significantly Augments the Efficacy of Cytarabine In Models of Acute Myeloid Leukemia

Disrupting NEDD8-Mediated Protein Turnover with MLN4924 Significantly Augments the Efficacy of Cytarabine

A New Rotary Powered Device for Bone Marrow Aspiration and Biopsy Yields Superior Specimens with Less Pain: Results of a Randomized Clinical Study

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia

Use of a New Rotary Powered Device for Bone Marrow Aspiration and Biopsy Yields Excellent Specimens Quickly and Efficiently.

MLN4924, A Novel First in Class Small Molecule Inhibitor of the Nedd8 Activating Enzyme (NAE), Has Potent Activity in Preclinical Models of Acute Myeloid Leukemia.

The Novel Orally Active Aurora A Kinase Inhibitor MLN8237 Is Highly Active in Preclinical Models of Acute Myeloid Leukemia and Significantly Increases the Efficacy of Cytarabine.

Email alerts

ASH Publications

American Society of Hematology

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