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Journal Articles

Targeting Pim Kinase Activity with the Novel Small Molecule Inhibitor SGI-1776 Significantly Augments the Efficacy of Cytarabine In Models of Acute Myeloid Leukemia

Kevin R Kelly, MD, Kelli Oberheu, B.S., Ernest Medina, B.S., Claudia M Espitia, MS, Devalingam Mahalingam, MD, PhD, Pietro Taverna, PhD, Gavin S. Choy, PharmD, MBA, Steffan T Nawrocki, PhD, Francis J. Giles, MB, MD, FRCPI, FRCPath, Jennifer S Carew, PhD
Journal: Blood
Blood (2010) 116 (21): 3253.
https://doi.org/10.1182/blood.V116.21.3253.3253
Published: 2010
Journal Articles

Disrupting NEDD8-Mediated Protein Turnover with MLN4924 Significantly Augments the Efficacy of Cytarabine

Steffan T Nawrocki, PhD, Kevin R Kelly, MD, Kelli Oberheu, B.S., Devalingam Mahalingam, MD, PhD, Peter G Smith, PhD, Jennifer S Carew, PhD
Journal: Blood
Blood (2010) 116 (21): 3255.
https://doi.org/10.1182/blood.V116.21.3255.3255
Published: 2010
Journal Articles

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia

Brief Report
Ronan T. Swords, Kevin R. Kelly, Peter G. Smith, James J. Garnsey, Devalingam Mahalingam, Ernest Medina, Kelli Oberheu, Swaminathan Padmanabhan, Michael O'Dwyer, Steffan T. Nawrocki, Francis J. Giles, Jennifer S. Carew
Journal: Blood
Blood (2010) 115 (18): 3796–3800.
https://doi.org/10.1182/blood-2009-11-254862
Published: 2010
Includes: Supplemental data