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Journal Articles

Integrated Preclinical Data Analysis of ISB 2001 Enables Optimal Starting Dose Selection for a First-in-Class Trispecific T Cell Engager Phase1 Study in Multiple Myeloma

Adam Drake, Maria Pihlgren, Vinu Menon, Daniela Pais, Laura Carretero-Iglesia, Jeremy Berret, Olivia Hall, Julie Macoin, Isabelle Gruber, Elodie Stainnack, Carole Estoppey, Cyrille Dreyfus, Girish Gudi, Tomomi Matsuura, Piet H van der Graft, Michael Dyson, Cyril Konto, Lida Pacaud, Ankita Srivastava, Eugene Zhukovsky, Mario Perro
Journal: Blood
Blood (2023) 142 (Supplement 1): 6574.
https://doi.org/10.1182/blood-2023-181546
Published: 2023
Journal Articles

Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma

Blandine Pouleau, Carole Estoppey, Perrine Suere, Emilie Nallet, Amélie Laurendon, Thierry Monney, Daniela Pais Ferreira, Adam Drake, Laura Carretero-Iglesia, Julie Macoin, Jérémy Berret, Maria Pihlgren, Marie-Agnès Doucey, Girish S. Gudi, Vinu Menon, Venkatesha Udupa, Abhishek Maiti, Gautam Borthakur, Ankita Srivastava, Stanislas Blein, M. Lamine Mbow, Thomas Matthes, Zeynep Kaya, Claire M. Edwards, James R. Edwards, Emmanuelle Menoret, Charlotte Kervoëlen, Catherine Pellat-Deceunynck, Philippe Moreau, Eugene Zhukovsky, Mario Perro, Myriam Chimen
Journal: Blood
Blood (2023) 142 (3): 260–273.
https://doi.org/10.1182/blood.2022019451
Published: 2023
Includes: Supplemental data
Journal Articles

ISB 2001, a First-in-Class Trispecific BCMA and CD38 T Cell Engager Designed to Overcome Mechanisms of Escape from Treatments for Multiple Myeloma By Targeting Two Antigens

Maria Pihlgren, Olivia Hall, Laura Carretero, Carole Estoppey, Adam Drake, Daniela Pais, Jeremy Loyau, Jeremy Berret, Isabelle Gruber, Perrine Suere, Vincent Schnorhk, Emilie Nallet, Blandine Pouleau, Myriam Chimen, Julie Macoin, Elodie Stainnack, Thierry Monney, Aurore Delachat, Cyrille Dreyfus, Thomas Matthes, Cyril Konto, Michael Dyson, Stanislas Blein, Lamine Mbow, Rebecca Wood, Ankita Srivastava, Eugene Zhukovsky, Mario Perro
Journal: Blood
Blood (2022) 140 (Supplement 1): 858–859.
https://doi.org/10.1182/blood-2022-159353
Published: 2022