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Claire M. Edwards
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Journal Articles

Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma

Blandine Pouleau, Carole Estoppey, Perrine Suere, Emilie Nallet, Amélie Laurendon, Thierry Monney, Daniela Pais Ferreira, Adam Drake, Laura Carretero-Iglesia, Julie Macoin, Jérémy Berret, Maria Pihlgren, Marie-Agnès Doucey, Girish S. Gudi, Vinu Menon, Venkatesha Udupa, Abhishek Maiti, Gautam Borthakur, Ankita Srivastava, Stanislas Blein, M. Lamine Mbow, Thomas Matthes, Zeynep Kaya, Claire M. Edwards, James R. Edwards, Emmanuelle Menoret, Charlotte Kervoëlen, Catherine Pellat-Deceunynck, Philippe Moreau, Eugene Zhukovsky, Mario Perro, Myriam Chimen
Journal: Blood
Blood (2023) 142 (3): 260–273.
https://doi.org/10.1182/blood.2022019451
Published: 2023
Includes: Supplemental data
Journal Articles

MGUS and SMM Plasma Cells Exhibit a Senescence-like Phenotype and Accumulation of Transposable Elements That May Contribute to Disease Progression

Gabriel Alvares Borges, Angelo Jose Guilatco, Christine M. Hachfeld, Ming Ruan, Sonya Royzenblat, Ming Xu, Claire M. Edwards, Marta Diaz-delCastillo, Thomas L. Andersen, Taxiarchis Kourelis, Tamar Tchkonia, James L. Kirkland, Matthew T. Drake, Megan Weivoda
Journal: Blood
Blood (2022) 140 (Supplement 1): 9966–9967.
https://doi.org/10.1182/blood-2022-170571
Published: 2022
Journal Articles

Altering Glycosphingolipid Composition to Improve Multiple Myeloma Bone Complication

Houfu Leng, MSc, DPhil, MBBS, BSc, Adel Ersek, PhD, Emma Morris, DPhil, Beatriz Gamez Molina, PhD, Claire M. Edwards, PhD, Nicole Horwood, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1942.
https://doi.org/10.1182/blood-2018-99-112237
Published: 2018
Journal Articles

Transcriptome Profiling of the Myeloma-Bone Niche Identifies BMP Signaling Role in Bone Destruction and Niche Maintenance, and Potential As a Therapeutic Target

Sarah Gooding, MD, Siobhan Webb, PhD, Sam Olechnowicz, PhD, Seint Lwin, PhD, Andrew Armitage, PhD, Karthik Ramasamy, Claire M. Edwards, PhD, Alexander Drakesmith, PhD
Journal: Blood
Blood (2016) 128 (22): 483.
https://doi.org/10.1182/blood.V128.22.483.483
Published: 2016
Journal Articles

BTK inhibition in myeloma: targeting the seed and the soil

Claire M. Edwards
Journal: Blood
Blood (2012) 120 (9): 1757–1759.
https://doi.org/10.1182/blood-2012-07-439216
Published: 2012
Journal Articles

Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease

Jessica A. Fowler, Seint T. Lwin, Matthew T. Drake, James R. Edwards, Robert A. Kyle, Gregory R. Mundy, Claire M. Edwards
Journal: Blood
Blood (2011) 118 (22): 5872–5882.
https://doi.org/10.1182/blood-2011-01-330407
Published: 2011
Includes: Supplemental data
Journal Articles

Osteoclasts in Myeloma Are Derived from Gr-1 + CD11b + Myeloid Immune Suppressor Cells of the Bone Marrow Niche in Vivo

Junling Zhuang, M.D., Ph.D., Li Yang, Ph.D., Seint T Lwin, B.S., Claire M. Edwards, PhD, BSc, James R Edwards, Ph.D., Gregory R Mundy, M.D.
Journal: Blood
Blood (2008) 112 (11): 736.
https://doi.org/10.1182/blood.V112.11.736.736
Published: 2008
Journal Articles

Wnt signaling: bone's defense against myeloma

Claire M. Edwards
Journal: Blood
Blood (2008) 112 (2): 216–217.
https://doi.org/10.1182/blood-2008-04-149278
Published: 2008
Journal Articles

Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo

Claire M. Edwards, James R. Edwards, Seint T. Lwin, Javier Esparza, Babatunde O. Oyajobi, Brandon McCluskey, Steven Munoz, Barry Grubbs, Gregory R. Mundy
Journal: Blood
Blood (2008) 111 (5): 2833–2842.
https://doi.org/10.1182/blood-2007-03-077685
Published: 2008
Journal Articles

Protein Profiling in Myeloma In Vivo ; Effects of Bortezomib in a Mouse Model of Myeloma.

Claire M. Edwards, PhD, Robert L. Caldwell, PhD, Andreia L. Bates, Jessica A. Fowler, James R. Edwards, PhD, Babatunde O. Oyajobi, MD, PhD, Seint T. Lwin, Jianghong Zhang, PhD, Gregory R. Mundy, MD
Journal: Blood
Blood (2007) 110 (11): 255.
https://doi.org/10.1182/blood.V110.11.255.255
Published: 2007
Journal Articles

Targeting Wnt Signaling in Myeloma In Vivo ; Differential Effects on Tumor Burden and Myeloma Bone Disease.

Claire M. Edwards, PhD, James R. Edwards, PhD, Seint T. Lwin, Gregory R. Mundy, MD
Journal: Blood
Blood (2007) 110 (11): 812.
https://doi.org/10.1182/blood.V110.11.812.812
Published: 2007