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Daniel Stephenson
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Journal Articles

Ferroptosis regulates hemolysis in stored murine and human red blood cells

Angelo D'Alessandro, Gregory R Keele, Ariel M Hay, Travis Nemkov, Eric J Earley, Daniel Stephenson, Matthew Vincent, Xutao Deng, Mars Stone, Monika Dzieciatkowska, Kirk C Hansen, Steven H Kleinman, Steven L Spitalnik, Nareg H Roubinian, Philip J Norris, Michael P Busch, Grier P Page, Brent Stockwell, Gary A Churchill, James C Zimring
Journal: Blood
Blood blood.2024026109.
https://doi.org/10.1182/blood.2024026109
Published: 2024
Includes: Supplemental data
Journal Articles

Arginine Metabolism Is a Biomarker of Red Blood Cell and Human Aging

Julie A Reisz Haines, Eric Earley, Travis Nemkov, Alicia Key, Daniel Stephenson, Gregory R Keele, Monika Dzieciatkowska, Steven L Spitalnik, Eldad A. Hod, Steven Kleinman, Nareg Roubinian, Mark Gladwin, Kirk C Hansen, Philip J Norris, Michael Paul Busch, James Zimring, Gary A Churchill, Grier P Page, Angelo D'Alessandro
Journal: Blood
Blood (2024) 144 (Supplement 1): 3835.
https://doi.org/10.1182/blood-2024-203178
Published: 2024
Journal Articles

Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro

Travis Nemkov, Alicia Key, Daniel Stephenson, Eric J. Earley, Gregory R. Keele, Ariel Hay, Pascal Amireault, Madeleine Casimir, Michaël Dussiot, Monika Dzieciatkowska, Julie A. Reisz, Xutao Deng, Mars Stone, Steve Kleinman, Steven L. Spitalnik, Kirk C. Hansen, Philip J. Norris, Gary A. Churchill, Michael P. Busch, Nareg Roubinian, Grier P. Page, James C. Zimring, Arduino Arduini, Angelo D’Alessandro
Journal: Blood
Blood (2024) 143 (24): 2517–2533.
https://doi.org/10.1182/blood.2024023983
Published: 2024
Includes: Supplemental data
Journal Articles

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo

Travis Nemkov, Daniel Stephenson, Christopher Erickson, Monika Dzieciatkowska, Alicia Key, Amy Moore, Eric J. Earley, Grier P. Page, Ian S. Lacroix, Mars Stone, Xutao Deng, Thomas Raife, Steven Kleinman, James C. Zimring, Nareg Roubinian, Kirk C. Hansen, Michael P. Busch, Philip J. Norris, Angelo D’Alessandro
Journal: Blood
Blood (2024) 143 (5): 456–472.
https://doi.org/10.1182/blood.2023022052
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic Polymorphisms in the Ferrireductase STEAP3 Regulate a Ferroptosis-like Process of Lipid Peroxidation-Induced Hemolysis in Murine and Human Red Blood Cells

Angelo D'Alessandro, Gregory R Keele, Ariel M Hay, Travis Nemkov, Daniel Stephenson, Xutao Deng, Mars Stone, Steven Kleinman, Steven Spitalnik, Philip J Norris, Michael Paul Busch, Gary A Churchill, James C Zimring
Journal: Blood
Blood (2023) 142 (Supplement 1): 697.
https://doi.org/10.1182/blood-2023-178760
Published: 2023
Journal Articles

Functional and Multi-Omics Signatures of Mitapivat Efficacy upon Activation of Pyruvate Kinase in Red Blood Cells from Patients with Sickle Cell Disease

Angelo D'Alessandro, Kang Le, Maureen Lundt, Quan Li, Emily Dunkelberger, Troy Cellmer, Andrew J Worth, Spurthi Patil, Chris Huston, Abby Grier, Monika monikA.dzieciatkow, Daniel Stephenson, William A Eaton, Swee Lay Thein
Journal: Blood
Blood (2023) 142 (Supplement 1): 2485.
https://doi.org/10.1182/blood-2023-181213
Published: 2023
Journal Articles

Multi-Omics Analysis of the Impact of Long Distance Trail Running on Red Blood Cells Highlights Acylcarnitine Mediated Lipid Damage Repair Mechanisms

Travis Nemkov, Emeric Stauffer, Francesca Cendali, Daniel Stephenson, Elie Nader, Melanie Robert, Sarah Skinner, Ian LaCroix, Monika Dzieciatkowska, Kirk C Hansen, Guillame Millet, Philippe Connes, Angelo D'Alessandro
Journal: Blood
Blood (2023) 142 (Supplement 1): 1075.
https://doi.org/10.1182/blood-2023-187074
Published: 2023
Journal Articles

Genetic Regulation of Carnitine Metabolism Controls Lipid Damage Repair Mechanisms and Hemolytic Propensity of Human Red Blood Cells during Aging In Vivo and in Vitro

Angelo D'Alessandro, Alicia Key, Pascal Amireault, Sandy Peltier, Eric Earley, Grier P Page, Travis Nemkov, Daniel Stephenson, Xutao Deng, Sonia Georgeault, Philippe Roingeard, Mars Stone, Steven Kleinman, Philip J Norris, Michael Paul Busch, Arduino Arduini
Journal: Blood
Blood (2023) 142 (Supplement 1): 4032.
https://doi.org/10.1182/blood-2023-178842
Published: 2023