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Philip J. Norris
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Journal Articles

Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro

Travis Nemkov, Alicia Key, Daniel Stephenson, Eric J. Earley, Gregory R. Keele, Ariel Hay, Pascal Amireault, Madeleine Casimir, Michaël Dussiot, Monika Dzieciatkowska, Julie A. Reisz, Xutao Deng, Mars Stone, Steve Kleinman, Steven L. Spitalnik, Kirk C. Hansen, Philip J. Norris, Gary A. Churchill, Michael P. Busch, Nareg Roubinian, Grier P. Page, James C. Zimring, Arduino Arduini, Angelo D’Alessandro
Journal: Blood
Blood (2024) 143 (24): 2517–2533.
https://doi.org/10.1182/blood.2024023983
Published: 2024
Includes: Supplemental data
Journal Articles

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo

Travis Nemkov, Daniel Stephenson, Christopher Erickson, Monika Dzieciatkowska, Alicia Key, Amy Moore, Eric J. Earley, Grier P. Page, Ian S. Lacroix, Mars Stone, Xutao Deng, Thomas Raife, Steven Kleinman, James C. Zimring, Nareg Roubinian, Kirk C. Hansen, Michael P. Busch, Philip J. Norris, Angelo D’Alessandro
Journal: Blood
Blood (2024) 143 (5): 456–472.
https://doi.org/10.1182/blood.2023022052
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic Polymorphisms in the Ferrireductase STEAP3 Regulate a Ferroptosis-like Process of Lipid Peroxidation-Induced Hemolysis in Murine and Human Red Blood Cells

Angelo D'Alessandro, Gregory R Keele, Ariel M Hay, Travis Nemkov, Daniel Stephenson, Xutao Deng, Mars Stone, Steven Kleinman, Steven Spitalnik, Philip J Norris, Michael Paul Busch, Gary A Churchill, James C Zimring
Journal: Blood
Blood (2023) 142 (Supplement 1): 697.
https://doi.org/10.1182/blood-2023-178760
Published: 2023
Journal Articles

Genetic Regulation of Carnitine Metabolism Controls Lipid Damage Repair Mechanisms and Hemolytic Propensity of Human Red Blood Cells during Aging In Vivo and in Vitro

Angelo D'Alessandro, Alicia Key, Pascal Amireault, Sandy Peltier, Eric Earley, Grier P Page, Travis Nemkov, Daniel Stephenson, Xutao Deng, Sonia Georgeault, Philippe Roingeard, Mars Stone, Steven Kleinman, Philip J Norris, Michael Paul Busch, Arduino Arduini
Journal: Blood
Blood (2023) 142 (Supplement 1): 4032.
https://doi.org/10.1182/blood-2023-178842
Published: 2023
Journal Articles

Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial

Clinical Trials & Observations
Pieter F. van der Meer, Paula F. Ypma, Nan van Geloven, Joost A. van Hilten, Rinie J. van Wordragen-Vlaswinkel, Okke Eissen, Jaap J. Zwaginga, Michael Trus, Erik A. M. Beckers, Peter te Boekhorst, Alan Tinmouth, Yulia Lin, Cyrus Hsia, David Lee, Philip J. Norris, Raymond P. Goodrich, Anneke Brand, Tor Hervig, Nancy M. Heddle, Johanna G. van der Bom, Jean-Louis H. Kerkhoffs
Journal: Blood
Blood (2018) 132 (2): 223–231.
https://doi.org/10.1182/blood-2018-02-831289
Published: 2018
Includes: Supplemental data
Journal Articles

Downregulation of Cytokines and Chemokines By GB Virus C after Transfusion-Transmission in HIV+ Blood Recipients

Marion Lanteri, PhD, Farnaz Vahidnia, MD MPH, PhD, Sylvia Tan, M.S., Jack Stapleton, MD, Philip J. Norris, MD, John W. Heitman, Xutao Deng, PhD, Sheila Keating, PhD, Donald Brambilla, PhD, Michael Busch, MD PhD, Brian Custer, PhD MPH
Journal: Blood
Blood (2014) 124 (21): 4122.
https://doi.org/10.1182/blood.V124.21.4122.4122
Published: 2014
Journal Articles

C1q-Binding HLA Antibodies Do Not Predict Platelet Transfusion Failure in TRAP Study Participant

Rachael P. Jackman, PhD, Douglas Bolgiano, Mila Lebedeva, Sherrill J. Slichter, MD, Philip J. Norris, MD
Journal: Blood
Blood (2014) 124 (21): 1562.
https://doi.org/10.1182/blood.V124.21.1562.1562
Published: 2014
Journal Articles

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro

Ali Danesh, Heather C. Inglis, Rachael P. Jackman, Shiquan Wu, Xutao Deng, Marcus O. Muench, John W. Heitman, Philip J. Norris
Journal: Blood
Blood (2014) 123 (5): 687–696.
https://doi.org/10.1182/blood-2013-10-530469
Published: 2014
Includes: Supplemental data
Journal Articles

Low-level HLA antibodies do not predict platelet transfusion failure in TRAP study participants

CME
Rachael P. Jackman, Xutao Deng, Douglas Bolgiano, Mila Lebedeva, John W. Heitman, Michael P. Busch, Sherrill J. Slichter, Philip J. Norris
Journal: Blood
Blood (2013) 121 (16): 3261–3266.
https://doi.org/10.1182/blood-2012-12-472779
Published: 2013
Includes: Supplemental data
Journal Articles

Transfusion-related acute lung injury: incidence and risk factors

Clinical Trials & Observations
Pearl Toy, Ognjen Gajic, Peter Bacchetti, Mark R. Looney, Michael A. Gropper, Rolf Hubmayr, Clifford A. Lowell, Philip J. Norris, Edward L. Murphy, Richard B. Weiskopf, Gregory Wilson, Monique Koenigsberg, Deanna Lee, Randy Schuller, Ping Wu, Barbara Grimes, Manish J. Gandhi, Jeffrey L. Winters, David Mair, Nora Hirschler, Rosa Sanchez Rosen, Michael A. Matthay, for the TRALI Study Group
Journal: Blood
Blood (2012) 119 (7): 1757–1767.
https://doi.org/10.1182/blood-2011-08-370932
Published: 2012
Includes: Supplemental data
Journal Articles

Expansion of CD8 + T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity

Emily M. Eriksson, Jeffrey M. Milush, Emily L. Ho, Mariana D. Batista, Sara J. Holditch, Chris E. Keh, Philip J. Norris, Sheila M. Keating, Steven G. Deeks, Peter W. Hunt, Jeffrey N. Martin, Michael G. Rosenberg, Frederick M. Hecht, Douglas F. Nixon
Journal: Blood
Blood (2012) 119 (3): 745–755.
https://doi.org/10.1182/blood-2010-12-324848
Published: 2012
Includes: Supplemental data
Journal Articles

Prevention of Alloimmunization and Induction of Partial Tolerance Following Transfusion with Pathogen Reduced Platelets in Mice

Rachael P. Jackman, Marcus O. Muench, John W. Heitman, Susanne Marschner, PhD, Raymond P. Goodrich, PhD, Philip J. Norris
Journal: Blood
Blood (2011) 118 (21): 718.
https://doi.org/10.1182/blood.V118.21.718.718
Published: 2011
Journal Articles

RBC-Derived Microparticles Evolve Over RBC Storage Time and Boost T Cell Mitogen Responses

Ali Danesh, Ph.D., Jacqueline Law, John W. Heitman, Philip J Norris
Journal: Blood
Blood (2011) 118 (21): 1256.
https://doi.org/10.1182/blood.V118.21.1256.1256
Published: 2011
Journal Articles

CD57 defines a functionally distinct population of mature NK cells in the human CD56 dim CD16 + NK-cell subset

Sandra Lopez-Vergès, Jeffrey M. Milush, Suchitra Pandey, Vanessa A. York, Janice Arakawa-Hoyt, Hanspeter Pircher, Philip J. Norris, Douglas F. Nixon, Lewis L. Lanier
Journal: Blood
Blood (2010) 116 (19): 3865–3874.
https://doi.org/10.1182/blood-2010-04-282301
Published: 2010
Includes: Supplemental data