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Journal Articles

Soluble CX3CL1/Fractalkine Is a New Player in the Pro-Inflammatory Microenvironment of Multiple Myeloma Patients Related to Bone Marrow Plasma Cell Infiltration and Neo-Vascularization

Anna Corcione, Valentina Marchica, Elisa Ferretti, Denise Toscani, PhD, Marina Bolzoni, PhD, Federica Costa, PhD, Cristina Mancini, MD, Eugenia Martella, MD, Fabrizio Accardi, MD, Laura Notarfranchi, MD, Domenico Ribatti, MD, Angelo Vacca, MD PhD, Franco Aversa, MD, Vito Pistoia, MD, Nicola Giuliani, MD PhD

Blood (2017) 130 (Supplement 1): 3044.

https://doi.org/10.1182/blood.V130.Suppl_1.3044.3044

Published: 2017

Journal Articles

Bone Marrow Remodelling and Topographic Redistribution of CD34 Positive Progenitors Characterize the Progression of Myelodysplastic Syndromes and Their Evolution to AML

Federico Quaini, MD PhD, Rodanthi Fioretzaki, MD, Monica Crugnola, MD, Angela Falco, PhD, Denise Madeddu, PhD, Luisa Craviotto, MD, Benedetta Cambò, MD, Lucia Prezioso, MD PhD, Gabriella Sammarelli, PhD, Giannalisa Todaro, PhD, Gallia Graiani, PhD, Cristina Mancini, MD, Eugenia Martella, MD, Francesca Re, MD, Nicola Giuliani, MD, PhD, Franco Aversa, MD

Blood (2016) 128 (22): 4302.

https://doi.org/10.1182/blood.V128.22.4302.4302

Published: 2016

Journal Articles

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target

Blood (2016) 128 (5): 667–679.

https://doi.org/10.1182/blood-2016-01-690743

Published: 2016

Includes: Supplemental data

Journal Articles

Expression Profile of CD38 and Related Ectoenzymes in Myeloma Bone Niche: A Rational Basis for the Use of Daratumumab to Inhibit Osteoclast Formation and Activity

Denise Toscani, PhD, Marina Bolzoni, PhD, Federica Costa, Valeria Quarona, Valentina Marchica, Cristina Mancini, MD, Eugenia Martella, MD, Sabrina Bonomini, Paola Storti, PhD, Antonella Chillemi, PhD, Fabrizio Accardi, MD, Benedetta Dalla Palma, MD, Luisa Craviotto, MD, Fabio Malavasi, MD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2015) 126 (23): 2959.

https://doi.org/10.1182/blood.V126.23.2959.2959

Published: 2015

Journal Articles

The Myeloma Cells Escape from Bone Marrow to Skin Extramedullary Localization upon Bortezomib Resistance: Role of CXCR4

Valentina Marchica, Fabrizio Accardi, MD, Paola Storti, PhD, Cristina Mancini, MD, Eugenia Martella, MD, Marina Bolzoni, PhD, Katia Todoerti, Chiara Schifano, Sabrina Bonomini, Benedetta Dalla Palma, MD, Magda Marcatti, MD, Maurilio Ponzoni, MD, Antonino Neri, MD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2015) 126 (23): 5315.

https://doi.org/10.1182/blood.V126.23.5315.5315

Published: 2015

Journal Articles

Hypoxia-Inducible Factor (HIF)-1alpha Inhibitionin Myeloma Cells Significantly Increases the Anti-Myeloma Effect of Lenalidomide in Vivo

Paola Storti, PhD, Valentina Marchica, Denise Toscani, PhD, Irma Airoldi, PhD, Sophie Maiga, PhD, Marina Bolzoni, PhD, Nicoletta Campanini, Eugenia Martella, MD, Cristina Mancini, MD, Valentina Ferri, Gaetano Donofrio, PhD, Martine Amiot, PhD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2015) 126 (23): 3012.

https://doi.org/10.1182/blood.V126.23.3012.3012

Published: 2015

Journal Articles

Galectin-1 Is Highly Expressed By Myeloma Cells and the Bone Marrow Microenvironment and Its Suppression Delineates a New Therapeutic in Vitro and in Vivo Strategy in Multiple Myeloma

Paola Storti, PhD, Gaetano Donofrio, PhD, Valentina Marchica, Daniela Guasco, Katia Todoerti, PhD, Irma Airoldi, PhD, Judith Anderson, Marina Bolzoni, Valentina Ferri, Eugenia Martella, MD, Cristina Mancini, MD, Nicoletta Campanini, Antonino Neri, G. David Roodman, MD, PhD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2014) 124 (21): 3373.

https://doi.org/10.1182/blood.V124.21.3373.3373

Published: 2014

Journal Articles

Proteasome Inhibitors Block Myeloma-Induced Osteocyte Death in Vitro and in Vivo in Multiple Myeloma Patients

Denise Toscani, Benedetta Dalla Palma, MD, Carla Palumbo, Marzia Ferretti, Marina Bolzoni, Daniela Guasco, Cristina Mancini, MD, Eugenia Martella, MD, Mirca Lazzaretti, PhD, Mario Pedrazzoni, MD, PhD, Franco Aversa, MD, Nicola Giuliani

Blood (2012) 120 (21): 3978.

https://doi.org/10.1182/blood.V120.21.3978.3978

Published: 2012

Journal Articles

Hypoxia-Inducible Factor (HIF)-1a Is A Therapeutic Target in Myeloma-Induced Angiogenesis and Bone Destruction in Vivo .

Marina Bolzoni, Paola Storti, PhD, Gaetano Donofrio, PhD, Irma Airoldi, PhD, Daniela Guasco, Denise Toscani, Marco Peronaci, Eugenia Martella, MD, Mirca Lazzaretti, PhD, Luca Agnelli, PhD, Ken Patrene, Cristina Mancini, MD, Martine Amiot, PhD, Antonino Neri, Simona Colla, Judith Anderson, Franco Aversa, MD, G. David Roodman, MD, PhD, Nicola Giuliani

Blood (2012) 120 (21): 2947.

https://doi.org/10.1182/blood.V120.21.2947.2947

Published: 2012

Journal Articles

Hypoxia-Inducible Factor (HIF)-1α Is a Therapeutic Target in Myeloma-Induced Angiogenesis

Paola Storti, PhD, Irma Airoldi, PhD, Marina Bolzoni, Mirca Lazzaretti, PhD, Daniela Guasco, Luca Agnelli, PhD, Eugenia Martella, MD, Cristina Mancini, MD, Antonino Neri, MD, Gaetano Donofrio, PhD, Nicola Giuliani, M.D., Ph.D.

Blood (2011) 118 (21): 3927.

https://doi.org/10.1182/blood.V118.21.3927.3927

Published: 2011

Journal Articles

The Activation of Wnt5a-Mediated Non Canonical Wnt Signaling in Human Bone Marrow Osteoprogenitor Cells Increases Osteoblastogenesis and Counterbalances the Inhibitory Effect of Myeloma Cells on Ror2/FZD5 Expression,

Marina Bolzoni, Paola Storti, PhD, Daniela Guasco, Mirca Lazzaretti, PhD, Eugenia Martella, MD, Cristina Mancini, MD, Luca Agnelli, PhD, Sabrina Bonomini, Antonino Neri, MD, Gaetano Donofrio, PhD, Nicola Giuliani, M.D., Ph.D.

Blood (2011) 118 (21): 3928.

https://doi.org/10.1182/blood.V118.21.3928.3928

Published: 2011

Journal Articles

Increased Osteocyte Apoptosis in Multiple Myeloma Patients: A Potential Role in Bone Remodeling Alterations Related to Osteolytic Bone Lesions.

Nicola Giuliani, Marzia Ferretti, Manuela Abeltino, Cristina Mancini, Eugenia Martella, Benedetta Dalla Palma, Marina Bolzoni, Valentina Sgobba, Paola Storti, Vittorio Rizzoli, Carla Palumbo

Blood (2009) 114 (22): 830.

https://doi.org/10.1182/blood.V114.22.830.830

Published: 2009

Journal Articles

HOXB7 Is Critically Involved in Multiple Myeloma-Induced Angiogenic Switch.

Paola Storti, Gaetano Donofrio, Marina Bolzoni, Simona Colla, Irma Airoldi, Valentina Sgobba, Manuela Abeltino, Katia Todoerti, Luca Agnelli, Mirca Lazzaretti, Cristina Mancini, Sabrina Bonomini, Domenico Ribatti, Vito Pistoia, Antonino Neri, Vittorio Rizzoli, Nicola Giuliani

Blood (2009) 114 (22): 125.

https://doi.org/10.1182/blood.V114.22.125.125

Published: 2009

Journal Articles

HOXB7 Overexpression in Mesenchymal Cells Stimulates the Production of Pro-Angiogenic Molecules: Potential Role in Multiple Myeloma Associated Angiogenesis

Simona Colla, Nicola Giuliani, Paola Storti, Mirca Lazzaretti, Katia Todoerti, Gina Lisignoli, Luca Agnelli, Cristina Manferdini, Sabrina Bonomini, Luisa Galla, Marina Bolzoni, Cristina Mancini, Gabriella Sammarelli, Marcellina Mangoni, Giorgio Lambertenghi Deliliers, Antonino Neri, Vittorio Rizzoli

Blood (2008) 112 (11): 2743.

https://doi.org/10.1182/blood.V112.11.2743.2743

Published: 2008

Journal Articles

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 α (HIF-1α) activity: involvement in myeloma-induced angiogenesis

Blood (2007) 110 (13): 4464–4475.

https://doi.org/10.1182/blood-2007-02-074617

Published: 2007

Journal Articles

The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients

Nicola Giuliani, Francesca Morandi, Sara Tagliaferri, Mirca Lazzaretti, Sabrina Bonomini, Monica Crugnola, Cristina Mancini, Eugenia Martella, Luca Ferrari, Antonio Tabilio, Vittorio Rizzoli

Blood (2007) 110 (1): 334–338.

https://doi.org/10.1182/blood-2006-11-059188

Published: 2007

Journal Articles

p29ING4 Regulates the Production of Pro-Angiogenic Molecules by Human Myeloma Cells in Normoxic and Hypoxic Conditions Being Involved in Myeloma-Induced Angiogenesis.

Sara Tagliaferri, Francesca Morandi, Paolo Lunghi, Simona Colla, Mirca Lazzaretti, Cristina Mancini, Daniela Drandi, Marco Ladetto, Antonio Bonati, Vittorio Rizzoli, Nicola Giuliani

Blood (2006) 108 (11): 515.

https://doi.org/10.1182/blood.V108.11.515.515

Published: 2006

Journal Articles

The Proteasome Inhibitor Bortezomib Affects Osteoblastogenesis and Bone Formation In Vitro and In Vivo in Multiple Myeloma Patients.

Nicola Giuliani, MD, PhD, Francesca Morandi, Sara Tagliaferri, Mirca Lazzaretti, PHD, Sabrina Bonomini, Monica Crugnola, MD, Daniela Petrò, MD, Cristina Mancini, MD, Eugenia Martella, MD, Vittorio Rizzoli, MD, PHD

Blood (2006) 108 (11): 508.

https://doi.org/10.1182/blood.V108.11.508.508

Published: 2006

Journal Articles

Angiopoietin-1 and Osteopontin Expression by CD138+ Myeloma Cells Rather Than VEGF and CD45 Correlates with Bone Marrow Angiogenesis in Multiple Myeloma Patients at the Diagnosis.

Nicola Giuliani, Simona Colla, Francesca Morandi, Sabrina Bonomini, Mirca Lazzaretti, Cristina Mancini, Monica Crugnola, Sara Tagliaferri, Rita Rizzato, Eugenia Martella, Gabriella Sammarelli, Luisa Craviotto, Cecilia Caramatti, Marcellina Mangoni, Vittorio Rizzoli

Blood (2005) 106 (11): 2501.

https://doi.org/10.1182/blood.V106.11.2501.2501

Published: 2005

Journal Articles

The Candidate Tumor Suppressor p29ING4 Is Down-Regulated in Human Myeloma Cells and Involved in Their Pro-Angiogenic Properties.

Nicola Giuliani, Francesca Morandi, Simona Colla, Sara Tagliaferri, Mirca Lazzaretti, Gabriella Sammarelli, Cristina Mancini, Sabrina Bonomini, Vittorio Rizzoli

Blood (2005) 106 (11): 2502.

https://doi.org/10.1182/blood.V106.11.2502.2502

Published: 2005

NARROW

Soluble CX3CL1/Fractalkine Is a New Player in the Pro-Inflammatory Microenvironment of Multiple Myeloma Patients Related to Bone Marrow Plasma Cell Infiltration and Neo-Vascularization

Bone Marrow Remodelling and Topographic Redistribution of CD34 Positive Progenitors Characterize the Progression of Myelodysplastic Syndromes and Their Evolution to AML

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target

Expression Profile of CD38 and Related Ectoenzymes in Myeloma Bone Niche: A Rational Basis for the Use of Daratumumab to Inhibit Osteoclast Formation and Activity

The Myeloma Cells Escape from Bone Marrow to Skin Extramedullary Localization upon Bortezomib Resistance: Role of CXCR4

Hypoxia-Inducible Factor (HIF)-1alpha Inhibitionin Myeloma Cells Significantly Increases the Anti-Myeloma Effect of Lenalidomide in Vivo

Galectin-1 Is Highly Expressed By Myeloma Cells and the Bone Marrow Microenvironment and Its Suppression Delineates a New Therapeutic in Vitro and in Vivo Strategy in Multiple Myeloma

Proteasome Inhibitors Block Myeloma-Induced Osteocyte Death in Vitro and in Vivo in Multiple Myeloma Patients

Hypoxia-Inducible Factor (HIF)-1a Is A Therapeutic Target in Myeloma-Induced Angiogenesis and Bone Destruction in Vivo .

Hypoxia-Inducible Factor (HIF)-1α Is a Therapeutic Target in Myeloma-Induced Angiogenesis

The Activation of Wnt5a-Mediated Non Canonical Wnt Signaling in Human Bone Marrow Osteoprogenitor Cells Increases Osteoblastogenesis and Counterbalances the Inhibitory Effect of Myeloma Cells on Ror2/FZD5 Expression,

Increased Osteocyte Apoptosis in Multiple Myeloma Patients: A Potential Role in Bone Remodeling Alterations Related to Osteolytic Bone Lesions.

HOXB7 Is Critically Involved in Multiple Myeloma-Induced Angiogenic Switch.

HOXB7 Overexpression in Mesenchymal Cells Stimulates the Production of Pro-Angiogenic Molecules: Potential Role in Multiple Myeloma Associated Angiogenesis

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 α (HIF-1α) activity: involvement in myeloma-induced angiogenesis

The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients

p29ING4 Regulates the Production of Pro-Angiogenic Molecules by Human Myeloma Cells in Normoxic and Hypoxic Conditions Being Involved in Myeloma-Induced Angiogenesis.

The Proteasome Inhibitor Bortezomib Affects Osteoblastogenesis and Bone Formation In Vitro and In Vivo in Multiple Myeloma Patients.

Angiopoietin-1 and Osteopontin Expression by CD138+ Myeloma Cells Rather Than VEGF and CD45 Correlates with Bone Marrow Angiogenesis in Multiple Myeloma Patients at the Diagnosis.

The Candidate Tumor Suppressor p29ING4 Is Down-Regulated in Human Myeloma Cells and Involved in Their Pro-Angiogenic Properties.

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American Society of Hematology

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American Society of Hematology

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