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Christoph Königs
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Journal Articles

First study of extended half-life rFVIIIFc in previously untreated patients with hemophilia A: PUPs A-LONG final results

Clinical Trials & Observations
Christoph Königs, Margareth C. Ozelo, Amy Dunn, Roshni Kulkarni, Beatrice Nolan, Simon A. Brown, Michele Schiavulli, Sriya Gunawardena, Sutirtha Mukhopadhyay, Deepthi Jayawardene, Bent Winding, Manuel Carcao
Journal: Blood
Blood (2022) 139 (26): 3699–3707.
https://doi.org/10.1182/blood.2021013563
Published: 2022
Includes: Supplemental data
Journal Articles

Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A

Joerg Kahle, Aleksander Orlowski, Diana Stichel, John F. Healey, Ernest T. Parker, Marc Jacquemin, Manuela Krause, Andreas Tiede, Dirk Schwabe, Pete Lollar, Christoph Königs
Journal: Blood
Blood (2017) 130 (6): 808–816.
https://doi.org/10.1182/blood-2016-11-751347
Published: 2017
Includes: Supplemental data
Journal Articles

FVIII-specific human chimeric antigen receptor T-regulatory cells suppress T- and B-cell responses to FVIII

Jeongheon Yoon, Anja Schmidt, Ai-Hong Zhang, Christoph Königs, Yong Chan Kim, David W. Scott
Journal: Blood
Blood (2017) 129 (2): 238–245.
https://doi.org/10.1182/blood-2016-07-727834
Published: 2017
Journal Articles

Inhibitor Development in Previously Untreated Patients with Severe Hemophilia a Treated with Nuwiq ® , a New Generation Recombinant FVIII of Human Origin

Raina Liesner, Marina Abashidze, Olga Aleinikova, PhD, Carmen Altisent, PhD, Mark J. Belletrutti, MD MSc, Annie Borel-Derlon, MD PhD, Manuel Carcao, MD, Hervé Chambost, Anthony Chan, MBBS, FRCP(C), FRCPath, Leonid Dubey, MD PhD, Jonathan M. Ducore, Fouzia Nambiathayil Abubacker, DM, Michael Gattens, Yves Gruel, MD, Natalya Kavardakova, Mohamed Khorassani, Anna Klukowska, Christoph Königs, MD PhD, Thierry Lambert, Sunil Lohade, Marianne Sigaud, MD, Valentin Turea, John K. Wu, MBBS, MSc, FRCPC, Vladimir Vdovin
Journal: Blood
Blood (2016) 128 (22): 327.
https://doi.org/10.1182/blood.V128.22.327.327
Published: 2016
Journal Articles

Risk Factors for the Development of High-Titer Inhibitors in 260 Children with Severe Hemophilia a Born Between 1990 and 2009: The Remain Study

Maria Elisa Mancuso, MD PhD, Kathelijn Fischer, MD PhD MSc, Elena Santagostino, MD PhD, Johannes Oldenburg, Prof, Helen Platokouki, MD, Christoph Königs, MD PhD, Carmen Escuriola, MD, Georges-Etienne Rivard, MD, Ana Cid, MD, Manuel Carcao, MD, Rolf Ljung, MD PhD, Pia Petrini, MD, Anne Rafowicz, MD, Carmen Altisent, MD, Gili Kenet, MD, Raina Liesner, Karin Kurnik, MD, Christel Van Geet, MD PhD, Teresa Alvarez-Roman, MD, Tin Tin Yee, MD, Guenter Auerswald, Sr., MD, Rosario Perez-Garrido, MD, Beatrice Nolan, Hervé Chambost, Anne Makipernaa, MD, Angelo Claudio Molinari, MD, Angela Thomas, MBBS, PhD, Elizabeth Chalmers, MD, Mike Williams, MD, Rainer Kobelt, MD, Marijke Van den Berg, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3774.
https://doi.org/10.1182/blood.V128.22.3774.3774
Published: 2016
Journal Articles

High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors

Glaivy Batsuli, Wei Deng, John F. Healey, Ernest T. Parker, W. Hunter Baldwin, Courtney Cox, Brenda Nguyen, Joerg Kahle, Christoph Königs, Renhao Li, Pete Lollar, Shannon L. Meeks
Journal: Blood
Blood (2016) 128 (16): 2055–2067.
https://doi.org/10.1182/blood-2016-02-701805
Published: 2016
Includes: Supplemental data
Journal Articles

Frequency and Epitope Specificity of Anti-Factor VIII C1 Domain Antibodies in Acquired and Hereditary Hemophilia Inhibitor Patient Plasma

Joerg Kahle, PhD, Aleksander Orlowski, Anja Schmidt, PhD, Kerstin Brettschneider, Thomas Klingebiel, MD, John F Healey, BS, Ernest T Parker, BA, John (Pete) S Lollar, MD, Marc Jacquemin, MD, Manuela Krause, MD, Andreas Tiede, MD PhD, Dirk Schwabe, MD, Christoph Königs, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3491.
https://doi.org/10.1182/blood.V126.23.3491.3491
Published: 2015
Journal Articles

Generation and Characterization of FVIII-Specific CAR-Transduced Regulatory T Cells

Anja Naumann, Yongchan Kim, PhD, Christoph Königs, MD PhD, David W Scott, PhD
Journal: Blood
Blood (2014) 124 (21): 236.
https://doi.org/10.1182/blood.V124.21.236.236
Published: 2014
Journal Articles

Anti-FVIII Autoantibodies Share Similar Characteristics In Acquired Hemophilia A Patients With and Without An Associated Disease

Joerg Kahle, PhD, Christoph Königs, MD, PhD, Anja Naumann, Thomas Klingebiel, MD, John F Healey, Ernest T Parker, B.A., Pete Lollar, MD, Dirk Schwabe, MD, Manuela Krause, MD
Journal: Blood
Blood (2013) 122 (21): 1110.
https://doi.org/10.1182/blood.V122.21.1110.1110
Published: 2013