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Journal Articles

Functional Consequences of Chromosomal Alterations in Angioimmunoblastic T-Cell Lymphoma

Huang Dachuan, Jason Yongsheng Chan, Choon Kiat Ong, Jing Quan Lim
Journal: Blood
Blood (2024) 144 (Supplement 1): 6180.
https://doi.org/10.1182/blood-2024-193215
Published: 2024
Journal Articles

Therapeutic Repurposing of Brincidofovir in Non-Hodgkin Lymphoma - Potential Synergy with Immune Checkpoint Blockade

Jason Yongsheng Chan, Elizabeth Chun Yong Lee, Kelila Xin Ye Chai, Boon Yee Lim, Zhimei Li, Jing Yi Lee, Bavani Kannan, Tun Kiat Ko, Jessica Sook-Ting Kok, Kah Suan Lim, Nur Ayuni Muhammad Taib, Dachuan Huang, Jing Quan Lim, Masatoshi Hazama, Koji Fukushima, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Blood
Blood (2024) 144 (Supplement 1): 4172.
https://doi.org/10.1182/blood-2024-202761
Published: 2024
Journal Articles

Frequent Copy Gains of Viral LMP-1 Confers Radiosensitivity in Natural-Killer/T Cell Lymphoma

Jing Quan Lim, Dachuan Huang, Kelila Xin Ye Chai, Phyu The, Kerry May Huifen Lim, Wendy Lee, Liang Wei Wang, Nur Ayuni Muhammad Taib, Beng Hooi Phang, Wee-Joo Chng, Olaf Rötzschke, Jason Yongsheng Chan, Soon Thye Lim, Jin-Xin BEI, Siok-Bian Ng, Choon Kiat Ong
Journal: Blood
Blood (2024) 144 (Supplement 1): 2963.
https://doi.org/10.1182/blood-2024-192976
Published: 2024
Journal Articles

Single-cell landscape of idiopathic multicentric Castleman disease in identical twins

Brief Report
Jason Yongsheng Chan, Jui Wan Loh, Jing Quan Lim, Herty Liany, Elizabeth Chun Yong Lee, Jing Yi Lee, Bavani Kannan, Boon Yee Lim, Zexi Guo, Kerry Lim, Jeslin Chian Hung Ha, Cedric Chuan-Young Ng, Tun Kiat Ko, Dachuan Huang, Dominique Yuan Bin Seow, Chee Leong Cheng, Sock Hoai Chan, Joanne Ngeow, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Blood
Blood (2024) 143 (18): 1837–1844.
https://doi.org/10.1182/blood.2023021992
Published: 2024
Includes: Supplemental data
Journal Articles

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma

Alyssa Bouska, Weiwei Zhang, Sunandini Sharma, Harald Holte, Ab Rauf Shah, Waseem Gul Lone, Luca Vincenzo Cappelli, Danilo Fiore, Qiang Gong, Tayla Heavican-Foral, Jeffrey Cannatella, Catalina Amador, Aiza Arif, Lynette Smith, Soon Thye Lim, Choon Kiat Ong, Andrew L. Feldman, Ming-Qing Du, Laurence de Leval, Timothy C. Greiner, Kai Fu, Gunhild Trøen, Daniel Vodak, Sigve Nakken, Jan Delabie, David M. Weinstock, Stefano A. Pileri, Antonella Laginestra, Kyeongjin Kim, Utpal Pajvani, Julie M. Vose, Dennis D Weisenburger, Sandeep Dave, Giorgio Inghirami, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2023) 142 (Supplement 1): 2993.
https://doi.org/10.1182/blood-2023-186530
Published: 2023
Journal Articles

Unraveling the Transcriptional Landscape of Nodular Lymphocyte-Predominant Hodgkin Lymphoma and T-Cell/Histiocyte Rich Large B-Cell Lymphoma: Impact of Tumor Microenvironment and Checkpoint Gene Expression

Ilja Kalashnikov, Veronica Russell, Panu Kovanen, Johannes Dunkel, Marja-Liisa Karjalainen-Lindsberg, Annika Pasanen, Rachel Kositsky, Sarah L. Ondrejka, Tanu Goyal, Eric D. Hsi, Mette Ølgod Pedersen, Anne Ortved Gang, Magdalena Czader, Jiehao Zhou, Mina Xu, Nathan Paulson, Jean L. Koff, Andrew G Evans, Yasodha Natkunam, Ridas Juskevicius, Abner Louissaint, Elizabeth Thacker, Tushar Dave, Cassandra L. Love, Chad M McCall, Choon Kiat Ong, Michael Churnetski, Haley Martin, Jennifer R. Chapman-Fredricks, Javeed Iqbal, Amy Chadburn, Payal Sojitra, Amir Behdad, William Choi, Jie Xu, Emily F. Ferguson Mason, Kikkeri N Naresh, Yuri D. Fedoriw, Dina Sameh Soliman, Sandeep Dave, Sirpa Leppä
Journal: Blood
Blood (2023) 142 (Supplement 1): 176.
https://doi.org/10.1182/blood-2023-182294
Published: 2023
Journal Articles

Therapeutic Repurposing of Brincidofovir in Natural Killer/T-Cell Lymphoma Reveals Potent Induction of Replication Stress, Sting Pathway Activation and Immunogenic Cell Death

Jason Yongsheng Chan, Elizabeth Chun Yong Lee, Kelila Xin Ye Chai, Jing Yi Lee, Bavani Kannan, Boon Yee Lim, Jessica Sook-Ting Kok, Zhimei Li, Jui Wan Loh, Tun Kiat Ko, Kah Suan Lim, Cedric Chuan-Young Ng, Kerry Lim, Dachuan Huang, Jing Quan Lim, Masatoshi Hazama, Koji Fukushima, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Blood
Blood (2022) 140 (Supplement 1): 2256–2257.
https://doi.org/10.1182/blood-2022-163243
Published: 2022
Journal Articles

Extranodal Marginal Zone Lymphomas Show Recurrent Mutations in DNA Repair Genes, Cancer-Associated Proliferative Signaling and NOTCH1 Signaling Pathways, Regardless of Anatomic Site

Jennifer R Chapman-Fredricks, Devang Thakkar, Juan Pablo Alderuccio, Kikkeri N Naresh, Sarah L. Ondrejka, Eric D. Hsi, Mina L Xu, Nathan Paulson, Jean L. Koff, David L Jaye, Jonathon B. Cohen, Anne Ortved Gang, Rebecca J Leeman-Neill, Tushar Dave, Lanie Happ, Cassandra Love, Sasan Zandi, Hina Naushad, Emily F Mason, Abner Louissaint, Jr., Haley Martin, Choon Kiat Ong, Raju Pillai, Mette Ø Pedersen, C. Cameron Yin, William Choi, Rex Kwok Him Au-Yeung, Marja-Liisa Karjalainen-Lindsberg, Amy Chadburn, Vincent Sarno, Matthew McKinney, Payal Sojitra, Andrew G Evans, Amir Behdad, Carlos Galvez, Chee Leong Cheng, Magdalena Czader, Jiong Yan, Sandeep S. Dave, Izidore S. Lossos
Journal: Blood
Blood (2022) 140 (Supplement 1): 6378–6380.
https://doi.org/10.1182/blood-2022-165616
Published: 2022
Journal Articles

Mutations of ATM Confer a Risk of Inferior Survival in Patients with TP53- wild Type Mantle Cell Lymphoma

Jean L. Koff, Rachel Kositsky, David L Jaye, Michael C. Churnetski, Katelin Baird, Colin B. O'Leary, Christopher R. Flowers, Sirpa Leppa, Marja-Liisa Karjalainen-Lindsberg, Shaoying Li, Jie Xu, Mette Ø Pedersen, Anne Ortved Gang, Kikkeri N Naresh, Rebecca J Leeman-Neill, Kwok Him Rex Au Yeung, Hina Naushad Qureishi, Javeed Iqbal, Jennifer R Chapman-Fredricks, Chad M. McCall, Michael Crump, Amy Chadburn, Erin C. Mulvey, Izidore S. Lossos, Sandra L. Ondrejka, Eric D. Hsi, Abner Louissaint, Jr., Haley Martin, Eric Tse, Cassandra Love, Tushar Dave, Clay Parker, Choon Kiat Ong, Andrew G Evans, Amir Behdad, Lixin Yang, Nishitha Reddy, Mary Ann Arildsen, Ridas Juskevicius, Jiong Yan, Magdalena Czader, Andrew M. Evens, Dina Sameh Soliman, Yuri Fedoriw, Sandeep S. Dave, Jonathon B. Cohen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3500–3503.
https://doi.org/10.1182/blood-2022-168002
Published: 2022
Journal Articles

Nodular Lymphocyte Predominant Hodgkin Lymphoma with Splenic Involvement Is Characterized By Inflamed Tumor Microenvironment, High Expression of Checkpoint Molecule Gene-Signature and Adverse Outcome

Ilja Kalashnikov, Marja-Liisa Karjalainen-Lindsberg, Panu Kovanen, Johannes Dunkel, Annika Pasanen, Rachel Kositsky, Sarah L. Ondrejka, Eric D. Hsi, Andrew G Evans, Mette Ø Pedersen, Peter H. Norgaard, Anne Ortved Gang, Magdalena Czader, Jiehao Zhou, Mina L Xu, Nathan Paulson, Ridas Juskevicius, Yasodha Natkunam, Abner Louissaint, Jr., Haley Martin, Elizabeth Thacker, Cassandra Love, Shari Tian, Choon Kiat Ong, Chee Leong Cheng, Chad M. McCall, Jean L. Koff, Sheren F. Younes, Mary Ann Arildsen, Jennifer R Chapman-Fredricks, Catalina Amador, Yuri Fedoriw, Carla Casulo, Amy Chadburn, Payal Sojitra, Amir Behdad, Eric Tse, Kikkeri N Naresh, C. Cameron Yin, Rashmi S. Goswami, Sandeep Dave, Sirpa Leppa
Journal: Blood
Blood (2022) 140 (Supplement 1): 3559–3561.
https://doi.org/10.1182/blood-2022-169476
Published: 2022
Journal Articles

A Non-Coding Variant in LOC105371512 Confers Susceptibility to Bleomycin-Induced Lung Injury

Joanne Lee, Hossein Tabatabaeian, Michelle Limei Poon, Nagavalli Somasundaram, Liu Xin, Yi Ching Yuen, Chia Meng Teoh, Benedict Yan, Esther Hian Li Chan, Yen Lin Chee, Sanjay De Mel, Bin Zhang, Xiao Hong Chew, Tiffany Tang, Chiea Chuen Khor, Joanne Yuen Yie Ngeow, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, E Shyong Tai, Kee Yuan Ngiam, Soo Chin Lee, Boon Cher Goh, Anand Devaprasath D. Jeyasekharan, Yvonne Tay, Folefac Aminkeng
Journal: Blood
Blood (2022) 140 (Supplement 1): 4542–4544.
https://doi.org/10.1182/blood-2022-169416
Published: 2022
Journal Articles

DNMT3A mutations define a unique biological and prognostic subgroup associated with cytotoxic T cells in PTCL-NOS

Tyler A. Herek, Alyssa Bouska, Waseem Lone, Sunandini Sharma, Catalina Amador, Tayla B. Heavican, Yuping Li, Qi Wei, Dylan Jochum, Timothy C. Greiner, Lynette Smith, Stefano Pileri, Andrew L. Feldman, Andreas Rosenwald, German Ott, Soon Thye Lim, Choon Kiat Ong, Joo Song, Elaine S. Jaffe, Gang Greg Wang, Louis Staudt, Lisa M. Rimsza, Julie Vose, Francesco d’Amore, Dennis D. Weisenburger, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2022) 140 (11): 1278–1290.
https://doi.org/10.1182/blood.2021015019
Published: 2022
Includes: Supplemental data
Journal Articles

A Clinical Prognostic Index for Angioimmunoblastic T Cell Lymphoma in an Asian Multi-Centre Study

Esther Chang, Valerie Shiwen Yang, Shin Yeu Ong, Hilda Kang, Ya Hwee Tan, Jianbang Chiang, Eileen Yi Ling Poon, Nagavalli Somasundaram, Mohamad Farid, Tiffany Tang, Miriam Tao, Lay Poh Khoo, Choon Kiat Ong, Soon Thye Lim, Jason Yongsheng Chan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2453.
https://doi.org/10.1182/blood-2021-147679
Published: 2021
Journal Articles

The Atlas of Blood Cancer Genomes (ABCG) Project: A Comprehensive Molecular Characterization of Leukemias and Lymphomas

Cassandra Love, Raju Pillai, Sarah L. Ondrejka, Govind Bhagat, Amy Chadburn, Matthew McKinney, Jean L. Koff, Dina Sameh Soliman, Magdalena Czader, Abner Louissaint, Jr., Shaoying Li, Choon Kiat Ong, Amir Behdad, Andrew M. Evens, Yasodha Natkunam, Peter H. Norgaard, Sirpa Leppa, Eric Tse, Jennifer R Chapman, Catalina Amador, Yuri Fedoriw, Agata M. Bogusz, Andrew G Evans, Rashmi S. Goswami, Ridas Juskevicius, Mina L. Xu, Kikkeri N Naresh, Barbara Xiong, Adam Snowden, Anabel Thurman, Eileen Smith, Tushar Dave, Rachel Kositsky, Devang Thakkar, Veronica Russell, Caroline J Roth, Sandeep Dave
Journal: Blood
Blood (2021) 138 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2021-151346
Published: 2021
Journal Articles

Genomic and Transcriptional Characterization of Primary Mediastinal Large B Cell Lymphoma

Rebecca J Leeman-Neill, Devang Thakkar, Sarah L. Ondrejka, Eric D. Hsi, Amy Chadburn, Mateo Mejia Saldarriaga, Sarah C. Rutherford, Chad M. McCall, Tareq Aljurf, Matthew McKinney, Jean L. Koff, David L Jaye, Jonathon B. Cohen, Dina Sameh Soliman, Abner Louissaint, Jr., Choon Kiat Ong, Chee Leong Cheng, Lianne Lee, Amir Behdad, Peter H. Norgaard, Andrew G Evans, Rashmi S. Goswami, Ridas Juskevicius, Mary Ann Arildsen, Kikkeri N Naresh, Caroline J Roth, Sandeep S. Dave, Govind Bhagat
Journal: Blood
Blood (2021) 138 (Supplement 1): 2398.
https://doi.org/10.1182/blood-2021-149745
Published: 2021
Journal Articles

ALK-Negative Anaplastic Large Cell Lymphomas Encompass Distinct Subgroups Including an ALK-Positive-like Subgroup with Favorable Prognosis

Kwok Him Rex Au Yeung, Veronica Russell, William Choi, Alice Wong, Lawrence Tsui, Yu Yan Carmen Lee, Jamilla Li, Harinder Gill, Ho-Wan Ip, Yok Lam Kwong, Tushar Dave, Sarah L. Ondrejka, Govind Bhagat, Amy Chadburn, Sarah C. Rutherford, Jean L. Koff, David L Jaye, Magdalena Czader, Abner Louissaint, Jr., Shaoying Li, Jie Xu, C. Cameron Yin, Choon Kiat Ong, Chee Leong Cheng, Amir Behdad, Andrew M. Evens, Peter H. Norgaard, Anne Ortved Gang, Sirpa Leppa, Marja-Liisa Karjalainen-Lindsberg, Jennifer R Chapman, Catalina Amador, Javeed Iqbal, Yuri Fedoriw, Agata M. Bogusz, Andrew G Evans, Ridas Juskevicius, Eric D. Hsi, Kikkeri N Naresh, Sandeep S. Dave, Eric Tse
Journal: Blood
Blood (2021) 138 (Supplement 1): 2403.
https://doi.org/10.1182/blood-2021-148807
Published: 2021
Journal Articles

Ambiguous Diagnosis of Nodal T-Cell Lymphomas with T-Follicular Helper (TFH) Phenotype and Hodgkin Lymphoma - a Multicenter Pilot Study

Esther Wei Yin Chang, Grace Fangmin Tan, Si Ting Goh, Talia Li Yin Lim, Shin Yeu Ong, Chandramouli Nagarajan, Nicholas Francis Grigoropoulos, Sanjay De Mel, Michelle Poon, Anand Devaprasath Jeyasekharan, Jianbang Chiang, Ya Hwee Tan, Valerie Yang, Eileen Yi Ling Poon, Nagavalli Somasundaram, Mohamad Farid, Miriam Tao, Chee Leong Cheng, Leonard Hwan Cheong Tan, Siok Bian Ng, Soo Yong Tan, Daryl Ming Zhe Cheah, Dachuan Huang, Jing Quan Lim, Soon Thye Lim, Choon Kiat Ong, Jason Yongsheng Chan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1403.
https://doi.org/10.1182/blood-2021-149358
Published: 2021
Journal Articles

Clinical Application of an Ex-Vivo Platform to Guide the Choice of Drug Combinations in Relapsed/Refractory Lymphoma; A Prospective Study

Sanjay De Mel, Jasmine Goh, Masturah Rashid, Michal Hoppe, Xi Yun Zhang, Patrick Jaynes, Esther KY Ng, Nur Atiqa Diana Binte Rahmat, Xin Liu, Michelle Poon, Hian Li Esther Chan, Joanne Lee, Yen-Lin Chee, Liang Piu Koh, Lip Kun Tan, Teck Guan Soh, Yi Ching Yuen, Hoi Yin Loi, Siok Bian Ng, Xueying Goh, Daryl Tan, Daryl Ming Zhe Cheah, Wan Lu Pang, Dachuan Huang, Nagavalli Somasundaram, Tiffany Tang, Jason Yongsheng Chan, Soon Thye Lim, Choon Kiat Ong, Wee Joo Chng, Edward KH Chow, Anand Jeyasekharan
Journal: Blood
Blood (2021) 138 (Supplement 1): 720.
https://doi.org/10.1182/blood-2021-149331
Published: 2021
Journal Articles

A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma

Clinical Trials & Observations
Xiao-Peng Tian, Shu-Yun Ma, Ken H. Young, Choon Kiat Ong, Yan-Hui Liu, Zhi-Hua Li, Qiong-Li Zhai, Hui-Qiang Huang, Tong-Yu Lin, Zhi-Ming Li, Zhong-Jun Xia, Li-Ye Zhong, Hui-Lan Rao, Mei Li, Jun Cai, Yu-Chen Zhang, Fen Zhang, Ning Su, Peng-Fei Li, Feng Zhu, Zijun Y. Xu-Monette, Esther Kam Yin Wong, Jeslin Chian Hung Ha, Lay Poh Khoo, Le Ai, Run-Fen Cheng, Jing Quan Lim, Sanjay de Mel, Siok-Bian Ng, Soon Thye Lim, Qing-Qing Cai
Journal: Blood
Blood (2021) 138 (6): 452–463.
https://doi.org/10.1182/blood.2020010637
Published: 2021
Includes: Supplemental data
Journal Articles

Avelumab for the treatment of relapsed or refractory extranodal NK/T-cell lymphoma: an open-label phase 2 study

Clinical Trials & Observations
Seok Jin Kim, Jing Quan Lim, Yurike Laurensia, Junhun Cho, Sang Eun Yoon, Ji Young Lee, Kyung Ju Ryu, Young Hyeh Ko, Youngil Koh, Duck Cho, Soon Thye Lim, Marie Beck Enemark, Francesco D’Amore, Mette Bjerre, Choon Kiat Ong, Won Seog Kim
Journal: Blood
Blood (2020) 136 (24): 2754–2763.
https://doi.org/10.1182/blood.2020007247
Published: 2020
Includes: Supplemental data