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Journal Articles

A Critical Role for PIM2 Kinase in Multiple Myeloma Through NF-κB Activation

Veerendra Munugalavadla, PhD, Leanne Berry, Jae Chang, Geoffrey Del Rosario, Jake Drummond, Changchun Du, Karen Fitzgerald, Lori S Friedman, Stephen E Gould, Heather Maecker, John Moffat, Dionysos Slaga, Xiaojing Xiaojing, Kristina West, Shang-Fan Yu, Allen J. Ebens, PhD
Journal: Blood
Blood (2011) 118 (21): 1839.
https://doi.org/10.1182/blood.V118.21.1839.1839
Published: 2011
Journal Articles

A Selective PIM Kinase Inhibitor Is Highly Active In Multiple Myeloma: Mechanism of Action and Signal Transduction Studies

Veerendra Munugalavadla, PhD, Leanne Berry, Yung-Hsiang Chen, Gauri Deshmukh, Jake Drummond, Changchun Du, Michael Eby, Karen Fitzgerald, Lori S. Friedman, Stephen E. Gould, Jane R. Kenny, Heather Maecker, John Moffat, Marina Moskalenko, Patricia Pacheco, Alham Saadat, Dion Slaga, Laura Sun, Gina Wang, Yagai Yang, Allen J. Ebens, PhD
Journal: Blood
Blood (2010) 116 (21): 4084.
https://doi.org/10.1182/blood.V116.21.4084.4084
Published: 2010
Journal Articles

A Selective PIM Kinase Inhibitor Is Highly Active In Multiple Myeloma: The Biology of Single Agent and PI3K/AKT/mTOR Combination Activity

Allen J. Ebens, PhD, Leanne Berry, Yung-Hsiang Chen, Gauri Deshmukh, Jake Drummond, Changchun Du, Michael Eby, Karen Fitzgerald, Lori S. Friedman, Stephen E. Gould, Jane R. Kenny, Heather Maecker, John Moffat, Marina Moskalenko, Patricia Pacheco, Alham Saadat, Dion Slaga, Laura Sun, Gina Wang, Yagai Yang, Veerendra Munugalavadla, PhD
Journal: Blood
Blood (2010) 116 (21): 3001.
https://doi.org/10.1182/blood.V116.21.3001.3001
Published: 2010
Journal Articles

CD40 Pathway Activation Status Predicts Response to CD40 Targeted Therapy in Diffuse Large b-Cell Lymphoma.

David Dornan, Ph.D, Bart Burington, Ph.D, Peng Yue, Ph.D, Xiaoyan Shi, Ph.D, Ranjana Advani, MD, Nancy Yu, Jeffrey T Lau, Shang-Fan Yu, Sven De Vos, MD, PhD, Stephen M Ansell, Andres Forero-Torres, MD, Zora Modrusan, Hartmut Koeppen, Teddy Yang, Changchun Du, BM, BS, Kristi Elkins, Andrew G. Polson, Rienk Offringa, Nancy Whiting, PharmD, BCOP, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 2721.
https://doi.org/10.1182/blood.V114.22.2721.2721
Published: 2009
Journal Articles

The PI3K Inhibitor GDC-0941 Induces Growth Arrest and Apoptosis of Acute Myeloid Leukemia Cells.

Laura Sun, Leanne Berry, Changchun Du, BM, BS, Xiaoju Max Ma, Lily Shi, Bruno C. Medeiros, MD, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 3787.
https://doi.org/10.1182/blood.V114.22.3787.3787
Published: 2009
Journal Articles

The PI3K Inhibitor GDC-0941 Synergizes with Standard of Care Therapies to Induce Growth Inhibition and Apoptosis of Multiple Myeloma Cells.

Veerendra Munugalavadla, PhD, Leanne Berry, Changchun Du, BM, BS, Sanjeev Mariathasan, Dion Slaga, Laura Sun, Marta Chesi, Peter Leif Bergsagel, MD, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 3788.
https://doi.org/10.1182/blood.V114.22.3788.3788
Published: 2009
Journal Articles

PI3K Signaling Pathway Activation Predicts Class I PI3K Inhibitor GDC-0941 Sensitivity in AML.

Xiaoju Max Ma, PhD, Changchun Du, BM, BS, Laura Sun, Xiaoyan Shi, Ph.D, Lori Friedman, David Dornan, Ph.D, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 1057.
https://doi.org/10.1182/blood.V114.22.1057.1057
Published: 2009
Journal Articles

Antibody-Drug Conjugates with Uncleavable Linkers for the Treatment of Non-Hodgkin Lymphoma.

Andrew G. Polson, PhD, Suzanna Clark, Changchun Du, Dan Eaton, Ph.D., Kristi Elkins, Reina N. Fuji, VMD, PhD, Mary Ann, Go, Alane Gray, Tom Januario, Hartmut Koeppen, M.D., Ph.D., Jeffery Lau, Will Leach, Elena McDorman, Ph.D., Kathleen McKeever, Ph.D., Saileta Prabhu, Ph.D., Suzie J. Scales, Ph.D., Dionysos Slaga, Susan Spencer, Marna Williams, Ph.D, David Xie, Shang-Fan Yu, Bing Zheng, Allen Ebens, PhD.
Journal: Blood
Blood (2007) 110 (11): 526.
https://doi.org/10.1182/blood.V110.11.526.526
Published: 2007
Journal Articles

Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma

Andrew G. Polson, Shang-Fan Yu, Kristi Elkins, Bing Zheng, Suzanna Clark, Gladys S. Ingle, Dionysos S. Slaga, Lynne Giere, Changchun Du, Christine Tan, Jo-Anne Hongo, Alvin Gogineni, Mary J. Cole, Richard Vandlen, Jean-Philippe Stephan, Judy Young, Wesley Chang, Suzie J. Scales, Sarajane Ross, Dan Eaton, Allen Ebens
Journal: Blood
Blood (2007) 110 (2): 616–623.
https://doi.org/10.1182/blood-2007-01-066704
Published: 2007
Includes: Supplemental data
Journal Articles

Antibody-Drug Conjugates Targeted to CD79 for the Treatment of Non-Hodgkin’s Lymphoma.

Andrew G. Polson, Shang-Fan Yu, Kristi Elkins, Bing Zheng, Suzanna Clark, Gladys Ingle, Dion Slaga, Lynne Giere, Changchun Du, Jean-Philippe Stephan, Judy Young, Richard Vandlen, Wesley Chang, Suzie Scales, Sarajane Ross, Dan Eaton, Allen Ebens
Journal: Blood
Blood (2006) 108 (11): 2524.
https://doi.org/10.1182/blood.V108.11.2524.2524
Published: 2006
Journal Articles

Overexpression of Wild-Type Retinoic Acid Receptor  (RAR) Recapitulates Retinoic Acid-Sensitive Transformation of Primary Myeloid Progenitors by Acute Promyelocytic Leukemia RAR-Fusion Genes

Changchun Du, Robert L. Redner, Michael P. Cooke, Catherine Lavau
Journal: Blood
Blood (1999) 94 (2): 793–802.
https://doi.org/10.1182/blood.V94.2.793
Published: 1999
Journal Articles

Sustained Gene Expression in Retrovirally Transduced, Engrafting Human Hematopoietic Stem Cells and Their Lympho-Myeloid Progeny

Linzhao Cheng, Changchun Du, Catherine Lavau, Shirley Chen, Jie Tong, Benjamin P. Chen, Roland Scollay, Robert G. Hawley, Beth Hill
Journal: Blood
Blood (1998) 92 (1): 83–92.
https://doi.org/10.1182/blood.V92.1.83.413k09_83_92
Published: 1998