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Journal Articles

A Critical Role for PIM2 Kinase in Multiple Myeloma Through NF-κB Activation

Veerendra Munugalavadla, PhD, Leanne Berry, Jae Chang, Geoffrey Del Rosario, Jake Drummond, Changchun Du, Karen Fitzgerald, Lori S Friedman, Stephen E Gould, Heather Maecker, John Moffat, Dionysos Slaga, Xiaojing Xiaojing, Kristina West, Shang-Fan Yu, Allen J. Ebens, PhD
Journal: Blood
Blood (2011) 118 (21): 1839.
https://doi.org/10.1182/blood.V118.21.1839.1839
Published: 2011
Journal Articles

CD40 Pathway Activation Status Predicts Response to CD40 Targeted Therapy in Diffuse Large b-Cell Lymphoma.

David Dornan, Ph.D, Bart Burington, Ph.D, Peng Yue, Ph.D, Xiaoyan Shi, Ph.D, Ranjana Advani, MD, Nancy Yu, Jeffrey T Lau, Shang-Fan Yu, Sven De Vos, MD, PhD, Stephen M Ansell, Andres Forero-Torres, MD, Zora Modrusan, Hartmut Koeppen, Teddy Yang, Changchun Du, BM, BS, Kristi Elkins, Andrew G. Polson, Rienk Offringa, Nancy Whiting, PharmD, BCOP, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 2721.
https://doi.org/10.1182/blood.V114.22.2721.2721
Published: 2009
Journal Articles

FcRL5 as a Target of Antibody-Drug Conjugates for the Treatment of Multiple Myeloma.

Andrew G. Polson, Bing Zheng, Kristi Elkins, Jeffery Lau, Mary Ann T. Go, Suzie J. Scales, Shang-Fan Yu, Marta Chesi, P. Leif Bergsagel, MD, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 3836.
https://doi.org/10.1182/blood.V114.22.3836.3836
Published: 2009
Journal Articles

Therapeutic potential of an anti-CD79b antibody–drug conjugate, anti–CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma

David Dornan, Fiona Bennett, Yvonne Chen, Mark Dennis, Dan Eaton, Kristi Elkins, Dorothy French, Mary Ann T. Go, Andrew Jack, Jagath R. Junutula, Hartmut Koeppen, Jeffrey Lau, Jacqueline McBride, Andy Rawstron, Xiaoyan Shi, Nancy Yu, Shang-Fan Yu, Peng Yue, Bing Zheng, Allen Ebens, Andrew G. Polson
Journal: Blood
Blood (2009) 114 (13): 2721–2729.
https://doi.org/10.1182/blood-2009-02-205500
Published: 2009
Includes: Supplemental data
Journal Articles

Identification of a Diagnostic Gene Signature for SGN-40, Anti-CD40 Monoclonal Antibody, in Pre-Clinical NHL Models and the Role of FAS in SGN-40 Mediated Apoptosis.

Xiaoyan Shi, Ph.D, Bart Burington, Ph.D, Tom Januario, Jeffrey T Lau, Shang-Fan Yu, Allen Ebens, Ph.D, David Dornan, Ph.D
Journal: Blood
Blood (2008) 112 (11): 1593.
https://doi.org/10.1182/blood.V112.11.1593.1593
Published: 2008
Journal Articles

Pharmacodynamics, Pharmacokinetics, and Tolerability of a B-Cell Specific Antibody-Targeted Chemotherapeutic Agent, Anti-CD79b-MCC-DM1, in Cynomolgus Monkeys

Marna Williams, Dongwei Li, Reina Fuji, Franklin Fuh, Saileta Prabhu, Bing Zheng, Kristi Elkins, Shang-Fan Yu, Josefa Chuh, Christine Tan, Joanne Hongo, Helga Raab, Judy Young, Sarajane Ross, Katherine Kozak, Dan Eaton, Susan D. Spencer, Kirsten A Poon, Paul Fielder, Jay Tibbitts, Karen Berry, William Manning, Vanitha Ramakrishnan, Allen Ebens, Andrew G. Polson
Journal: Blood
Blood (2008) 112 (11): 4974.
https://doi.org/10.1182/blood.V112.11.4974.4974
Published: 2008
Journal Articles

Development and Therapeutic Potential of an Anti-CD79b Antibody-Drug Conjugate, Anti-CD79b-Vc-MMAE, for the Treatment of Non-Hodgkin’s Lymphoma

Andrew G. Polson, Fiona L Bennett, Yvonne Chen, Mark Dennis, Dan Eaton, Allen Ebens, Kristi Elkins, Dorothy French, Mary Ann T. Go, Andrew S Jack, Jagath Junutula, Hartmut Koeppen, Jeffery Lau, Jacqueline McBride, Lily Shi, Andy Rawston, Shang-Fan Yu, Peng Yue, Bing Zheng, David Dornan
Journal: Blood
Blood (2008) 112 (11): 2618.
https://doi.org/10.1182/blood.V112.11.2618.2618
Published: 2008
Journal Articles

Antibody-Drug Conjugates with Uncleavable Linkers for the Treatment of Non-Hodgkin Lymphoma.

Andrew G. Polson, PhD, Suzanna Clark, Changchun Du, Dan Eaton, Ph.D., Kristi Elkins, Reina N. Fuji, VMD, PhD, Mary Ann, Go, Alane Gray, Tom Januario, Hartmut Koeppen, M.D., Ph.D., Jeffery Lau, Will Leach, Elena McDorman, Ph.D., Kathleen McKeever, Ph.D., Saileta Prabhu, Ph.D., Suzie J. Scales, Ph.D., Dionysos Slaga, Susan Spencer, Marna Williams, Ph.D, David Xie, Shang-Fan Yu, Bing Zheng, Allen Ebens, PhD.
Journal: Blood
Blood (2007) 110 (11): 526.
https://doi.org/10.1182/blood.V110.11.526.526
Published: 2007
Journal Articles

Pharmacokinetics of Anti-CD22 Antibody Conjugates with Uncleavable and Cleavable Linkers in Rats.

Dong Xie, Rong Deng, Jakub Baudys, Pam Chan, Randy Dere, Allen Ebens, Paul Fielder, Reina Fuji, Alane Gray, Catherine Hung, Suhas Iyer, Kathleen McKeever, Margaret Kenrick, Will Leach, Andrew Polson, Ola Saad, Jean-Philippe Stephan, Ben Quan Shen, Jay Tibbitts, Shang-Fan Yu, Saileta Prabhu
Journal: Blood
Blood (2007) 110 (11): 2361.
https://doi.org/10.1182/blood.V110.11.2361.2361
Published: 2007
Journal Articles

Non-Clinical Pharmacology of Anti-CD22 Antibody Drug Conjugates.

Dong Xie, Jakub Baudys, Pam Chan, Rong Deng, Randy Dere, Allen Ebens, Paul Fielder, Franklin Fuh, Reina Fuji, Alane Gray, Catherine Huang, Shasha Jumbe, Kathleen Makeever, Ola Saad, Jean-Philippe Stephan, Jay Tibbitts, Marna Williams, Shang-Fan Yu, Saileta Prabhu
Journal: Blood
Blood (2007) 110 (11): 2363.
https://doi.org/10.1182/blood.V110.11.2363.2363
Published: 2007
Journal Articles

Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma

Andrew G. Polson, Shang-Fan Yu, Kristi Elkins, Bing Zheng, Suzanna Clark, Gladys S. Ingle, Dionysos S. Slaga, Lynne Giere, Changchun Du, Christine Tan, Jo-Anne Hongo, Alvin Gogineni, Mary J. Cole, Richard Vandlen, Jean-Philippe Stephan, Judy Young, Wesley Chang, Suzie J. Scales, Sarajane Ross, Dan Eaton, Allen Ebens
Journal: Blood
Blood (2007) 110 (2): 616–623.
https://doi.org/10.1182/blood-2007-01-066704
Published: 2007
Includes: Supplemental data
Journal Articles

Antibody-Drug Conjugates Targeted to CD79 for the Treatment of Non-Hodgkin’s Lymphoma.

Andrew G. Polson, Shang-Fan Yu, Kristi Elkins, Bing Zheng, Suzanna Clark, Gladys Ingle, Dion Slaga, Lynne Giere, Changchun Du, Jean-Philippe Stephan, Judy Young, Richard Vandlen, Wesley Chang, Suzie Scales, Sarajane Ross, Dan Eaton, Allen Ebens
Journal: Blood
Blood (2006) 108 (11): 2524.
https://doi.org/10.1182/blood.V108.11.2524.2524
Published: 2006